STRINGSTRING
PV10_07396 PV10_07396 PV10_07087 PV10_07087 PV10_08562 PV10_08562 PV10_01595 PV10_01595 PV10_01307 PV10_01307 PV10_00523 PV10_00523 PV10_03294 PV10_03294 PV10_03105 PV10_03105 MCM7 MCM7 PV10_04833 PV10_04833 PV10_01431 PV10_01431 PV10_01372 PV10_01372 PV10_00894 PV10_00894 PV10_02688 PV10_02688 PV10_02466 PV10_02466 PV10_02294 PV10_02294 PV10_05118 PV10_05118 PV10_04499 PV10_04499 PV10_03762 PV10_03762 PV10_05932 PV10_05932 PV10_01469 PV10_01469 PV10_07984 PV10_07984 PV10_08211 PV10_08211 PV10_04329 PV10_04329 PV10_07844 PV10_07844 PV10_01305 PV10_01305 PV10_07084 PV10_07084 PV10_00844 PV10_00844 B0A52_00659 B0A52_00659 PV10_08569 PV10_08569 PV10_02150 PV10_02150 PV10_04710 PV10_04710 PV10_04585 PV10_04585 PV10_05180 PV10_05180 PV10_04309 PV10_04309 PV10_04229 PV10_04229 PV10_04813 PV10_04813 PV10_04579 PV10_04579 PV10_06514 PV10_06514 PV10_06587 PV10_06587 PV10_06484 PV10_06484 PV10_06387 PV10_06387 PV10_07553 PV10_07553 B0A52_01520 B0A52_01520 PV10_08689 PV10_08689 PV10_07047 PV10_07047 PV10_08112 PV10_08112 PV10_01681 PV10_01681 PV10_01113 PV10_01113 PV10_03207 PV10_03207 FEN1 FEN1 PV10_04251 PV10_04251 B0A52_07266 B0A52_07266 PV10_05646 PV10_05646 PV10_07753 PV10_07753
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_07396AAA domain-containing protein. (397 aa)
PV10_07087DNA polymerase. (1453 aa)
PV10_08562Uncharacterized protein. (1692 aa)
PV10_01595Sld5 domain-containing protein. (182 aa)
PV10_01307Vezatin domain-containing protein. (585 aa)
PV10_00523DNA primase; Belongs to the eukaryotic-type primase small subunit family. (530 aa)
PV10_03294Uncharacterized protein. (790 aa)
PV10_03105DNA ligase. (855 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
PV10_04833Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (750 aa)
PV10_01431Replication factor C subunit 1. (1078 aa)
PV10_01372CBFD_NFYB_HMF domain-containing protein. (349 aa)
PV10_00894Replication factor C subunit 5. (597 aa)
PV10_02688Uncharacterized protein. (507 aa)
PV10_02466Cell division control protein; Belongs to the CDC6/cdc18 family. (624 aa)
PV10_02294Uncharacterized protein. (504 aa)
PV10_05118Uncharacterized protein. (226 aa)
PV10_04499DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (654 aa)
PV10_03762Uncharacterized protein. (370 aa)
PV10_05932DNA helicase; Belongs to the MCM family. (963 aa)
PV10_01469DNA helicase; Belongs to the MCM family. (915 aa)
PV10_07984UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (338 aa)
PV10_08211Sld5 domain-containing protein. (236 aa)
PV10_04329DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (249 aa)
PV10_07844Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
PV10_01305Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (267 aa)
PV10_07084DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2242 aa)
PV10_00844Uncharacterized protein. (474 aa)
B0A52_00659Ubiquitin-40S ribosomal protein S27a. (154 aa)
PV10_08569Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (477 aa)
PV10_02150Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (413 aa)
PV10_04710CBFD_NFYB_HMF domain-containing protein. (185 aa)
PV10_04585Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (675 aa)
PV10_05180AAA domain-containing protein. (1122 aa)
PV10_04309DNA_LIGASE_A3 domain-containing protein. (1122 aa)
PV10_04229Uncharacterized protein. (444 aa)
PV10_04813DNA polymerase. (1107 aa)
PV10_04579Uncharacterized protein. (132 aa)
PV10_06514DNA helicase; Belongs to the MCM family. (1004 aa)
PV10_06587AAA domain-containing protein. (406 aa)
PV10_06484Zds_C domain-containing protein. (930 aa)
PV10_06387DNA_pol_E_B domain-containing protein. (856 aa)
PV10_07553Serine/threonine-protein kinase pef1; Belongs to the protein kinase superfamily. (412 aa)
B0A52_01520Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (328 aa)
PV10_08689BZIP domain-containing protein. (291 aa)
PV10_07047DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (245 aa)
PV10_08112Uncharacterized protein. (158 aa)
PV10_01681DNA helicase; Belongs to the MCM family. (863 aa)
PV10_01113DNA ligase. (870 aa)
PV10_03207Polyubiquitin. (229 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
PV10_04251DNA helicase; Belongs to the MCM family. (724 aa)
B0A52_07266RING-box protein 1. (124 aa)
PV10_05646Replication factor C subunit 4. (352 aa)
PV10_07753DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (507 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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