38 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_07024	Uncharacterized protein. (556 aa)
	PV10_08138	Uncharacterized protein. (425 aa)
	PV10_06913	CDC73_C domain-containing protein. (446 aa)
	PV10_05645	CFEM domain-containing protein. (281 aa)
	PV10_00312	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (856 aa)
	PV10_08535	Uncharacterized protein. (487 aa)
	PV10_05811	Uncharacterized protein. (1242 aa)
	PV10_05897	CYCLIN domain-containing protein; Belongs to the cyclin family. (403 aa)
	B0A52_02609	S1 domain-containing protein. (169 aa)
	PV10_01985	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1083 aa)
	PV10_02580	Uncharacterized protein. (621 aa)
	PV10_03372	Uncharacterized protein. (973 aa)
	PV10_03603	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1262 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	PV10_01859	Uncharacterized protein. (673 aa)
	B0A52_01817	RPOL4c domain-containing protein. (152 aa)
	PV10_08543	Uncharacterized protein. (386 aa)
	B0A52_01643	Uncharacterized protein. (152 aa)
	PV10_05390	Uncharacterized protein. (849 aa)
	PV10_06403	Nuclear cap-binding protein subunit 2. (175 aa)
	PV10_06724	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	PV10_06302	Uncharacterized protein. (556 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_04961	RPOLD domain-containing protein. (337 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	B0A52_09440	Uncharacterized protein. (238 aa)
	PV10_02098	RING-type domain-containing protein. (269 aa)
	PV10_02711	DNA repair helicase rad15. (818 aa)
	PV10_03006	RNA_pol_L_2 domain-containing protein. (122 aa)
	PV10_03478	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_00654	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_06700	TFIIS N-terminal domain-containing protein. (401 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01643	B0A52_01817	A0A0D1Z529	A0A0D1Z4K7	Uncharacterized protein.	RPOL4c domain-containing protein.	0.999
B0A52_01643	B0A52_02609	A0A0D1Z529	A0A0D1XUD0	Uncharacterized protein.	S1 domain-containing protein.	0.999
B0A52_01643	B0A52_09440	A0A0D1Z529	A0A0D1ZJS0	Uncharacterized protein.	Uncharacterized protein.	0.999
B0A52_01643	PV10_00274	A0A0D1Z529	A0A0D1Y6N2	Uncharacterized protein.	Plus3 domain-containing protein.	0.909
B0A52_01643	PV10_00312	A0A0D1Z529	A0A0D1X3N9	Uncharacterized protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.883
B0A52_01643	PV10_00388	A0A0D1Z529	A0A0D1Y777	Uncharacterized protein.	Uncharacterized protein.	0.862
B0A52_01643	PV10_00436	A0A0D1Z529	A0A0D1ZPS5	Uncharacterized protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
B0A52_01643	PV10_00654	A0A0D1Z529	A0A0D1ZQE5	Uncharacterized protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.947
B0A52_01643	PV10_01196	A0A0D1Z529	A0A0D1ZU44	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.981
B0A52_01643	PV10_01662	A0A0D1Z529	A0A0D1ZTU8	Uncharacterized protein.	Uncharacterized protein.	0.978
B0A52_01643	PV10_01859	A0A0D1Z529	A0A0D1YBX6	Uncharacterized protein.	Uncharacterized protein.	0.655
B0A52_01643	PV10_01985	A0A0D1Z529	A0A0D1Y107	Uncharacterized protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.995
B0A52_01643	PV10_02041	A0A0D1Z529	A0A0D2A5G3	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.874
B0A52_01643	PV10_02098	A0A0D1Z529	A0A0D1ZK71	Uncharacterized protein.	RING-type domain-containing protein.	0.972
B0A52_01643	PV10_02580	A0A0D1Z529	A0A0D1Y2N7	Uncharacterized protein.	Uncharacterized protein.	0.839
B0A52_01643	PV10_02711	A0A0D1Z529	A0A0D1ZKA8	Uncharacterized protein.	DNA repair helicase rad15.	0.975
B0A52_01643	PV10_03006	A0A0D1Z529	A0A0D1ZL15	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.999
B0A52_01643	PV10_03372	A0A0D1Z529	A0A0D1Y4Z9	Uncharacterized protein.	Uncharacterized protein.	0.931
B0A52_01643	PV10_03478	A0A0D1Z529	A0A0D1ZMK2	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
B0A52_01643	PV10_03603	A0A0D1Z529	A0A0D1Y5W5	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999