15 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01591	Zn(2)-C6 fungal-type domain-containing protein. (757 aa)
	PV10_06952	Uncharacterized protein. (284 aa)
	PV10_08689	BZIP domain-containing protein. (291 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (607 aa)
	PV10_05154	OTU domain-containing protein. (412 aa)
	PV10_00578	MIT domain-containing protein. (1192 aa)
	PV10_00090	Uncharacterized protein. (587 aa)
	B0A52_00659	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	PV10_08688	Zn(2)-C6 fungal-type domain-containing protein. (754 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (660 aa)
	PV10_03762	Uncharacterized protein. (370 aa)
	PV10_09001	Zn(2)-C6 fungal-type domain-containing protein. (728 aa)
	PV10_09023	Fungal_trans domain-containing protein. (842 aa)
	PV10_03207	Polyubiquitin. (229 aa)
	PV10_07946	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (272 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_00659	GUF1	A0A0D1ZQI9	A0A0D1ZQR0	Ubiquitin-40S ribosomal protein S27a.	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	0.652
B0A52_00659	PV10_00090	A0A0D1ZQI9	A0A0D1ZQE2	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.684
B0A52_00659	PV10_00578	A0A0D1ZQI9	A0A0D1ZQ64	Ubiquitin-40S ribosomal protein S27a.	MIT domain-containing protein.	0.652
B0A52_00659	PV10_03207	A0A0D1ZQI9	A0A0D1Y4J0	Ubiquitin-40S ribosomal protein S27a.	Polyubiquitin.	0.969
B0A52_00659	PV10_03762	A0A0D1ZQI9	A0A0D2A0A3	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.681
B0A52_00659	PV10_05154	A0A0D1ZQI9	A0A0D1ZH87	Ubiquitin-40S ribosomal protein S27a.	OTU domain-containing protein.	0.687
B0A52_00659	PV10_06952	A0A0D1ZQI9	A0A0D1Z483	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.752
GUF1	B0A52_00659	A0A0D1ZQR0	A0A0D1ZQI9	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin-40S ribosomal protein S27a.	0.652
GUF1	PV10_03207	A0A0D1ZQR0	A0A0D1Y4J0	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Polyubiquitin.	0.590
GUF1	PV10_08689	A0A0D1ZQR0	A0A0D1Z5B3	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	BZIP domain-containing protein.	0.652
MDM34	PV10_01591	A0A0D1Z6L0	A0A0D1YB81	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.846
MDM34	PV10_07946	A0A0D1Z6L0	A0A0D1Z2U0	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.846
MDM34	PV10_08688	A0A0D1Z6L0	A0A0D1ZQP2	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.846
MDM34	PV10_09001	A0A0D1Z6L0	A0A0D1XIT5	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.846
MDM34	PV10_09023	A0A0D1Z6L0	A0A0D1XIV4	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Fungal_trans domain-containing protein.	0.846
PV10_00090	B0A52_00659	A0A0D1ZQE2	A0A0D1ZQI9	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a.	0.684
PV10_00090	PV10_03207	A0A0D1ZQE2	A0A0D1Y4J0	Uncharacterized protein.	Polyubiquitin.	0.688
PV10_00090	PV10_08689	A0A0D1ZQE2	A0A0D1Z5B3	Uncharacterized protein.	BZIP domain-containing protein.	0.684
PV10_00578	B0A52_00659	A0A0D1ZQ64	A0A0D1ZQI9	MIT domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.652
PV10_00578	PV10_03207	A0A0D1ZQ64	A0A0D1Y4J0	MIT domain-containing protein.	Polyubiquitin.	0.590