(39 nodes) Steroid biosynthesis network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_08920	Uncharacterized protein. (259 aa)
	PV10_05598	Uncharacterized protein. (267 aa)
	PV10_05650	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (357 aa)
	PV10_04595	Ammonium_transp domain-containing protein. (452 aa)
	PV10_02072	PNPLA domain-containing protein. (671 aa)
	PV10_02082	Uncharacterized protein. (313 aa)
	PV10_00292	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (384 aa)
	PV10_00834	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (408 aa)
	PV10_01660	S5A_REDUCTASE domain-containing protein. (328 aa)
	PV10_01765	Uncharacterized protein. (446 aa)
	PV10_08971	O-acyltransferase. (547 aa)
	PV10_08380	Ammonium transporter. (490 aa)
	PV10_05418	SE domain-containing protein. (491 aa)
	PV10_05846	Uncharacterized protein. (772 aa)
	PV10_06689	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (740 aa)
	PV10_02396	Farnesyl-diphosphate farnesyltransferase. (489 aa)
	PV10_01756	Uncharacterized protein. (202 aa)
	PV10_09029	Uncharacterized protein. (485 aa)
	PV10_08083	Uncharacterized protein. (366 aa)
	PV10_08205	Uncharacterized protein. (233 aa)
	PV10_07257	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (297 aa)
	PV10_07247	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (717 aa)
	PV10_05317	Uncharacterized protein. (349 aa)
	PV10_06506	3Beta_HSD domain-containing protein. (429 aa)
	PV10_06573	Ammonium transporter. (492 aa)
	PV10_06155	AB hydrolase-1 domain-containing protein. (696 aa)
	PV10_06668	Ammonium transporter. (546 aa)
	PV10_06729	Uncharacterized protein; Belongs to the cytochrome P450 family. (523 aa)
	PV10_06781	Uncharacterized protein. (587 aa)
	PV10_04900	Ammonium transporter. (496 aa)
	PV10_00064	FAD-binding PCMH-type domain-containing protein. (533 aa)
	PV10_03289	Abhydro_lipase domain-containing protein. (698 aa)
	PV10_07420	EXPERA domain-containing protein. (260 aa)
	PV10_01368	EXPERA domain-containing protein. (262 aa)
	PV10_01654	Uncharacterized protein; Belongs to the cytochrome P450 family. (532 aa)
	PV10_03804	Ammonium transporter. (482 aa)
	PV10_05286	Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (493 aa)
	PV10_02323	Uncharacterized protein; Belongs to the cytochrome P450 family. (538 aa)
	PV10_02877	Uncharacterized protein. (877 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV10_00064	PV10_00292	A0A0D1ZNF2	A0A0D1X3M6	FAD-binding PCMH-type domain-containing protein.	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	0.771
PV10_00064	PV10_00834	A0A0D1ZNF2	A0A0D1X5K6	FAD-binding PCMH-type domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.853
PV10_00064	PV10_01368	A0A0D1ZNF2	A0A0D1ZUM1	FAD-binding PCMH-type domain-containing protein.	EXPERA domain-containing protein.	0.840
PV10_00064	PV10_01765	A0A0D1ZNF2	A0A0D1X828	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.876
PV10_00064	PV10_02072	A0A0D1ZNF2	A0A0D1WXV5	FAD-binding PCMH-type domain-containing protein.	PNPLA domain-containing protein.	0.766
PV10_00064	PV10_02082	A0A0D1ZNF2	A0A0D1WXW7	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_02323	A0A0D1ZNF2	A0A0D2A6H8	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.924
PV10_00064	PV10_02396	A0A0D1ZNF2	A0A0D1Y269	FAD-binding PCMH-type domain-containing protein.	Farnesyl-diphosphate farnesyltransferase.	0.530
PV10_00064	PV10_02877	A0A0D1ZNF2	A0A0D2A888	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_05418	A0A0D1ZNF2	A0A0D1XRS0	FAD-binding PCMH-type domain-containing protein.	SE domain-containing protein.	0.540
PV10_00064	PV10_05598	A0A0D1ZNF2	A0A0D1WPQ5	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_05650	A0A0D1ZNF2	A0A0D1WPW0	FAD-binding PCMH-type domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.885
PV10_00064	PV10_06506	A0A0D1ZNF2	A0A0D1ZBH8	FAD-binding PCMH-type domain-containing protein.	3Beta_HSD domain-containing protein.	0.496
PV10_00064	PV10_06689	A0A0D1ZNF2	A0A0D1XVC2	FAD-binding PCMH-type domain-containing protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.922
PV10_00064	PV10_06729	A0A0D1ZNF2	A0A0D1ZE91	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.901
PV10_00064	PV10_06781	A0A0D1ZNF2	A0A0D1ZEG7	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.850
PV10_00064	PV10_07247	A0A0D1ZNF2	A0A0D1Z7G1	FAD-binding PCMH-type domain-containing protein.	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	0.757
PV10_00064	PV10_07257	A0A0D1ZNF2	A0A0D1Z514	FAD-binding PCMH-type domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.887
PV10_00064	PV10_07420	A0A0D1ZNF2	A0A0D1ZTI3	FAD-binding PCMH-type domain-containing protein.	EXPERA domain-containing protein.	0.581
PV10_00064	PV10_08205	A0A0D1ZNF2	A0A0D1Z3T6	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553