94 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_05772	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
	PV10_05823	Uncharacterized protein. (569 aa)
	PV10_06227	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	PV10_03813	Uncharacterized protein. (373 aa)
	PV10_06389	Acetoacetate-CoA ligase. (940 aa)
	PV10_06431	Uncharacterized protein. (311 aa)
	PV10_03724	Aldedh domain-containing protein. (478 aa)
	PV10_04852	Importin N-terminal domain-containing protein. (952 aa)
	PV10_04948	3-hydroxyisobutyrate dehydrogenase. (336 aa)
	PV10_04163	Acetoacetate-CoA ligase. (725 aa)
	PV10_05049	Uncharacterized protein. (678 aa)
	PV10_05185	Uncharacterized protein. (264 aa)
	PV10_04598	Uncharacterized protein. (560 aa)
	PV10_09228	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
	PV10_09113	SET domain-containing protein. (540 aa)
	PV10_08198	Uncharacterized protein. (440 aa)
	PV10_08272	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	PV10_08691	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
	PV10_07069	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
	PV10_07549	Acetoacetate-CoA ligase. (677 aa)
	PV10_05292	Transket_pyr domain-containing protein. (391 aa)
	B0A52_06985	Isovaleryl-CoA dehydrogenase, mitochondrial. (435 aa)
	PV10_05929	Uncharacterized protein. (454 aa)
	PV10_06105	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (482 aa)
	PV10_06678	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (455 aa)
	PV10_06767	Acetoacetate-CoA ligase. (703 aa)
	PV10_03769	Uncharacterized protein. (434 aa)
	PV10_04350	Uncharacterized protein. (452 aa)
	PV10_04989	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	PV10_05138	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (282 aa)
	PV10_02723	Uncharacterized protein. (404 aa)
	PV10_03064	Branched-chain amino acid aminotransferase. (379 aa)
	PV10_03460	Uncharacterized protein. (287 aa)
	PV10_00513	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (486 aa)
	PV10_00760	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (491 aa)
	PV10_00785	Acetoacetate-CoA ligase. (730 aa)
	PV10_01550	CoA carboxyltransferase C-terminal domain-containing protein. (693 aa)
	PV10_01713	Uncharacterized protein. (315 aa)
	PV10_07954	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
	PV10_07976	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (577 aa)
	PV10_08005	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (473 aa)
	PV10_05787	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
	PV10_06144	Uncharacterized protein. (730 aa)
	PV10_04563	Methylmalonate-semialdehyde dehydrogenase (Acylating). (544 aa)
	PV10_04886	Uncharacterized protein. (1168 aa)
	PV10_05203	Uncharacterized protein. (535 aa)
	PV10_02498	Uncharacterized protein. (456 aa)
	PV10_02913	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (437 aa)
	PV10_01344	Uncharacterized protein. (464 aa)
	PV10_01484	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
	PV10_09051	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
	PV10_08449	Uncharacterized protein. (882 aa)
	PV10_08729	Fungal_trans domain-containing protein. (541 aa)
	PV10_08132	Methylmalonate-semialdehyde dehydrogenase (Acylating). (570 aa)
	PV10_08719	Uncharacterized protein. (537 aa)
	PV10_07721	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (548 aa)
	PV10_07778	Transket_pyr domain-containing protein. (389 aa)
	PV10_05380	Homoserine O-acetyltransferase. (532 aa)
	PV10_05450	AB hydrolase-1 domain-containing protein. (585 aa)
	PV10_06264	Zn(2)-C6 fungal-type domain-containing protein. (782 aa)
	PV10_05730	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (521 aa)
	PV10_05738	Pyr_redox_2 domain-containing protein. (138 aa)
	PV10_04642	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	PV10_02000	Uncharacterized protein. (624 aa)
	PV10_02519	Uncharacterized protein. (572 aa)
	PV10_02351	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (545 aa)
	PV10_03235	Fungal_trans domain-containing protein. (649 aa)
	PV10_08209	Pyr_redox_2 domain-containing protein. (347 aa)
	PV10_08456	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
	PV10_00544	Uncharacterized protein. (1601 aa)
	PV10_00139	Uncharacterized protein. (333 aa)
	PV10_00754	Uncharacterized protein. (304 aa)
	PV10_08730	Acetoacetate-CoA ligase. (677 aa)
	PV10_00230	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (524 aa)
	PV10_00240	Uncharacterized protein. (244 aa)
	PV10_08791	Uncharacterized protein. (471 aa)
	PV10_00934	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
	PV10_00370	Dihydrolipoyl dehydrogenase. (516 aa)
	PV10_07687	Pyruvate carboxyltransferase domain-containing protein. (624 aa)
	PV10_01857	Uncharacterized protein. (256 aa)
	PV10_01302	APH domain-containing protein. (370 aa)
	PV10_01883	Uncharacterized protein. (714 aa)
	PV10_06164	Uncharacterized protein. (347 aa)
	PV10_03777	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (521 aa)
	PV10_04253	Zn(2)-C6 fungal-type domain-containing protein. (844 aa)
	PV10_05163	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
	PV10_02520	Uncharacterized protein. (881 aa)
	PV10_03404	Uncharacterized protein. (448 aa)
	PV10_00629	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (461 aa)
	PV10_00873	Uncharacterized protein. (352 aa)
	PV10_01277	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (531 aa)
	PV10_01411	SET domain-containing protein. (485 aa)
	PV10_01538	Pyruvate carboxyltransferase domain-containing protein. (367 aa)
	PV10_01663	Uncharacterized protein. (146 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_06985	PV10_00230	A0A0D1WPA4	A0A0D1ZQU5	Isovaleryl-CoA dehydrogenase, mitochondrial.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.474
B0A52_06985	PV10_00240	A0A0D1WPA4	A0A0D1ZQV8	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.460
B0A52_06985	PV10_00370	A0A0D1WPA4	A0A0D1ZRG9	Isovaleryl-CoA dehydrogenase, mitochondrial.	Dihydrolipoyl dehydrogenase.	0.434
B0A52_06985	PV10_00513	A0A0D1WPA4	A0A0D1X4H2	Isovaleryl-CoA dehydrogenase, mitochondrial.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.410
B0A52_06985	PV10_00629	A0A0D1WPA4	A0A0D2ACZ9	Isovaleryl-CoA dehydrogenase, mitochondrial.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.410
B0A52_06985	PV10_00754	A0A0D1WPA4	A0A0D1ZQT4	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.714
B0A52_06985	PV10_00760	A0A0D1WPA4	A0A0D1X572	Isovaleryl-CoA dehydrogenase, mitochondrial.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.410
B0A52_06985	PV10_00785	A0A0D1WPA4	A0A0D1X590	Isovaleryl-CoA dehydrogenase, mitochondrial.	Acetoacetate-CoA ligase.	0.468
B0A52_06985	PV10_00873	A0A0D1WPA4	A0A0D2ADY5	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.661
B0A52_06985	PV10_00934	A0A0D1WPA4	A0A0D1ZRC1	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.659
B0A52_06985	PV10_01277	A0A0D1WPA4	A0A0D2AF69	Isovaleryl-CoA dehydrogenase, mitochondrial.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.410
B0A52_06985	PV10_01302	A0A0D1WPA4	A0A0D1ZUH0	Isovaleryl-CoA dehydrogenase, mitochondrial.	APH domain-containing protein.	0.593
B0A52_06985	PV10_01344	A0A0D1WPA4	A0A0D1YAH5	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.595
B0A52_06985	PV10_01484	A0A0D1WPA4	A0A0D1YAV5	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.659
B0A52_06985	PV10_01550	A0A0D1WPA4	A0A0D1X7K7	Isovaleryl-CoA dehydrogenase, mitochondrial.	CoA carboxyltransferase C-terminal domain-containing protein.	0.629
B0A52_06985	PV10_02000	A0A0D1WPA4	A0A0D1ZHW2	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.406
B0A52_06985	PV10_02351	A0A0D1WPA4	A0A0D1ZL05	Isovaleryl-CoA dehydrogenase, mitochondrial.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.410
B0A52_06985	PV10_02498	A0A0D1WPA4	A0A0D1Y2F3	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.761
B0A52_06985	PV10_02519	A0A0D1WPA4	A0A0D1ZJI0	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.674
B0A52_06985	PV10_02520	A0A0D1WPA4	A0A0D2A6X9	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.622