(111 nodes) Tyrosine metabolism network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_04803	PKS_ER domain-containing protein. (338 aa)
	PV10_05256	HpcH_HpaI domain-containing protein. (208 aa)
	PV10_02058	MFS domain-containing protein. (567 aa)
	PV10_02153	Aminotran_1_2 domain-containing protein. (412 aa)
	PV10_02450	Uncharacterized protein. (543 aa)
	PV10_02655	Uncharacterized protein. (548 aa)
	PV10_02660	MFS domain-containing protein. (560 aa)
	PV10_00150	AAA domain-containing protein. (812 aa)
	PV10_00530	Uncharacterized protein. (444 aa)
	PV10_00627	ADH_zinc_N domain-containing protein. (270 aa)
	PV10_00801	PKS_ER domain-containing protein. (363 aa)
	PV10_01938	Aminotran_1_2 domain-containing protein. (398 aa)
	PV10_08994	Fumarylacetoacetase. (436 aa)
	PV10_08045	PKS_ER domain-containing protein. (317 aa)
	PV10_08193	Fumarylacetoacetase. (430 aa)
	PV10_08362	HpcH_HpaI domain-containing protein. (291 aa)
	PV10_08520	MFS domain-containing protein. (542 aa)
	PV10_07177	MFS domain-containing protein. (562 aa)
	PV10_07438	4-hydroxyphenylpyruvate dioxygenase. (420 aa)
	PV10_08935	Aldedh domain-containing protein. (511 aa)
	PV10_07237	FAA_hydrolase domain-containing protein. (297 aa)
	PV10_07254	Aminotran_1_2 domain-containing protein. (557 aa)
	PV10_07404	Amine oxidase. (487 aa)
	PV10_07603	Uncharacterized protein. (338 aa)
	PV10_05865	Amine oxidase. (687 aa)
	PV10_05942	Uncharacterized protein. (109 aa)
	PV10_06051	Amine oxidase. (500 aa)
	PV10_06804	Uncharacterized protein. (306 aa)
	PV10_06122	PKS_ER domain-containing protein. (322 aa)
	PV10_03969	Amine oxidase. (790 aa)
	PV10_04078	Maleylacetoacetate isomerase; Belongs to the GST superfamily. (233 aa)
	PV10_04940	MFS domain-containing protein. (524 aa)
	PV10_04991	Amine oxidase. (687 aa)
	PV10_05096	Fungal_trans domain-containing protein. (654 aa)
	PV10_04254	Aminotran_1_2 domain-containing protein. (614 aa)
	PV10_04284	Fe-ADH domain-containing protein. (413 aa)
	PV10_05209	Aldolase_II domain-containing protein. (276 aa)
	PV10_02036	Uncharacterized protein. (1101 aa)
	PV10_09066	Homogentisate 1,2-dioxygenase. (369 aa)
	PV10_08312	PKS_ER domain-containing protein. (356 aa)
	PV10_00544	Uncharacterized protein. (1601 aa)
	PV10_03606	Aminotran_1_2 domain-containing protein. (448 aa)
	PV10_00553	Alcohol dehydrogenase 1. (357 aa)
	PV10_06828	AMMECR1 domain-containing protein. (340 aa)
	PV10_01457	Amine oxidase. (493 aa)
	PV10_08118	PKS_ER domain-containing protein. (491 aa)
	PV10_08191	Homogentisate 1,2-dioxygenase. (521 aa)
	PV10_08463	PKS_ER domain-containing protein. (375 aa)
	PV10_08770	Aminotran_1_2 domain-containing protein. (365 aa)
	PV10_06854	MFS domain-containing protein. (511 aa)
	PV10_06903	Uncharacterized protein. (883 aa)
	PV10_06928	Uncharacterized protein. (95 aa)
	PV10_07206	FAA_hydrolase domain-containing protein. (235 aa)
	PV10_07694	Uncharacterized protein. (566 aa)
	PV10_05288	Uncharacterized protein. (128 aa)
	PV10_05731	PKS_ER domain-containing protein. (376 aa)
	PV10_06128	Amine oxidase. (700 aa)
	PV10_06450	Uncharacterized protein. (546 aa)
	PV10_06702	Uncharacterized protein. (338 aa)
	PV10_06717	PKS_ER domain-containing protein. (379 aa)
	PV10_03720	Uncharacterized protein. (553 aa)
	PV10_03764	MFS domain-containing protein. (545 aa)
	PV10_04870	Uncharacterized protein. (155 aa)
	PV10_01969	Fe-ADH domain-containing protein. (360 aa)
	PV10_02245	PKS_ER domain-containing protein. (368 aa)
	PV10_02654	Zn(2)-C6 fungal-type domain-containing protein. (485 aa)
	PV10_03339	MJ1316 domain-containing protein. (185 aa)
	PV10_03501	Homogentisate 1,2-dioxygenase. (461 aa)
	PV10_03531	Uncharacterized protein. (328 aa)
	PV10_03673	Amine oxidase. (250 aa)
	B0A52_01131	FAA_hydrolase domain-containing protein. (287 aa)
	PV10_01773	Uncharacterized protein. (357 aa)
	PV10_06972	Uncharacterized protein. (243 aa)
	PV10_07234	Aspartate aminotransferase. (463 aa)
	PV10_05590	Amine oxidase. (512 aa)
	PV10_06245	Uncharacterized protein. (535 aa)
	PV10_06407	Zn(2)-C6 fungal-type domain-containing protein. (763 aa)
	PV10_06572	MFS domain-containing protein. (221 aa)
	PV10_03909	Fumarylacetoacetase. (436 aa)
	PV10_04091	MFS domain-containing protein. (545 aa)
	PV10_04399	Fe-ADH domain-containing protein. (493 aa)
	PV10_04413	Amine oxidase. (498 aa)
	PV10_01945	FAA_hydrolase domain-containing protein. (221 aa)
	PV10_01629	PKS_ER domain-containing protein. (379 aa)
	PV10_00773	Fungal_trans domain-containing protein. (760 aa)
	PV10_00721	Aldedh domain-containing protein. (496 aa)
	PV10_02382	PKS_ER domain-containing protein. (356 aa)
	PV10_02172	PKS_ER domain-containing protein. (360 aa)
	PV10_02051	Aspartate aminotransferase. (424 aa)
	PV10_04556	FAA_hydrolase domain-containing protein. (299 aa)
	PV10_04415	Amine oxidase. (497 aa)
	PV10_06805	ATP-grasp domain-containing protein. (492 aa)
	PV10_05941	Uncharacterized protein. (300 aa)
	PV10_05780	PKS_ER domain-containing protein. (406 aa)
	PV10_01941	PKS_ER domain-containing protein. (344 aa)
	PV10_05372	Amine oxidase. (683 aa)
	PV10_01324	Aspartate aminotransferase. (427 aa)
	PV10_07708	Amine oxidase. (602 aa)
	PV10_01807	DUF1907 domain-containing protein. (338 aa)
	PV10_07617	Amine oxidase. (491 aa)
	PV10_01111	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (492 aa)
	PV10_01628	Tyrosinase_Cu-bd domain-containing protein. (344 aa)
	PV10_07430	PKS_ER domain-containing protein. (374 aa)
	PV10_00879	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (381 aa)
	PV10_05098	Fumarylacetoacetase. (426 aa)
	PV10_02411	Succinate-semialdehyde dehydrogenase. (537 aa)
	PV10_02509	Histidinol-phosphate transaminase. (438 aa)
	PV10_02408	Uncharacterized protein. (475 aa)
	PV10_02423	Amine oxidase. (815 aa)
	PV10_09212	Uncharacterized protein. (345 aa)
	PV10_00266	MFS domain-containing protein. (544 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01131	PV10_00721	A0A0D1X4J6	A0A0D2ADC6	FAA_hydrolase domain-containing protein.	Aldedh domain-containing protein.	0.508
B0A52_01131	PV10_01111	A0A0D1X4J6	A0A0D1ZTU2	FAA_hydrolase domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.508
B0A52_01131	PV10_01773	A0A0D1X4J6	A0A0D1X832	FAA_hydrolase domain-containing protein.	Uncharacterized protein.	0.405
B0A52_01131	PV10_02411	A0A0D1X4J6	A0A0D1ZJ77	FAA_hydrolase domain-containing protein.	Succinate-semialdehyde dehydrogenase.	0.508
B0A52_01131	PV10_03501	A0A0D1X4J6	A0A0D1X2A7	FAA_hydrolase domain-containing protein.	Homogentisate 1,2-dioxygenase.	0.599
B0A52_01131	PV10_04078	A0A0D1X4J6	A0A0D1ZDM0	FAA_hydrolase domain-containing protein.	Maleylacetoacetate isomerase; Belongs to the GST superfamily.	0.405
B0A52_01131	PV10_08191	A0A0D1X4J6	A0A0D1WI99	FAA_hydrolase domain-containing protein.	Homogentisate 1,2-dioxygenase.	0.599
B0A52_01131	PV10_08935	A0A0D1X4J6	A0A0D1Z635	FAA_hydrolase domain-containing protein.	Aldedh domain-containing protein.	0.508
B0A52_01131	PV10_09066	A0A0D1X4J6	A0A0D1ZMZ1	FAA_hydrolase domain-containing protein.	Homogentisate 1,2-dioxygenase.	0.599
PV10_00150	PV10_00544	A0A0D1Y6E3	A0A0D1ZQ21	AAA domain-containing protein.	Uncharacterized protein.	0.624
PV10_00150	PV10_01324	A0A0D1Y6E3	A0A0D1ZUI9	AAA domain-containing protein.	Aspartate aminotransferase.	0.556
PV10_00150	PV10_06804	A0A0D1Y6E3	A0A0D1ZCD8	AAA domain-containing protein.	Uncharacterized protein.	0.583
PV10_00544	PV10_00150	A0A0D1ZQ21	A0A0D1Y6E3	Uncharacterized protein.	AAA domain-containing protein.	0.624
PV10_00544	PV10_01324	A0A0D1ZQ21	A0A0D1ZUI9	Uncharacterized protein.	Aspartate aminotransferase.	0.774
PV10_00544	PV10_01938	A0A0D1ZQ21	A0A0D1YC44	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.546
PV10_00544	PV10_02051	A0A0D1ZQ21	A0A0D2A5H4	Uncharacterized protein.	Aspartate aminotransferase.	0.705
PV10_00544	PV10_02153	A0A0D1ZQ21	A0A0D1Y1F2	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.546
PV10_00544	PV10_07234	A0A0D1ZQ21	A0A0D1XP25	Uncharacterized protein.	Aspartate aminotransferase.	0.705
PV10_00544	PV10_07438	A0A0D1ZQ21	A0A0D1Z5K4	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.780
PV10_00544	PV10_07694	A0A0D1ZQ21	A0A0D1WMY3	Uncharacterized protein.	Uncharacterized protein.	0.781