93 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01694	SPX domain-containing protein. (933 aa)
	PV10_08292	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (516 aa)
	PV10_08331	Protein kinase domain-containing protein. (1274 aa)
	B0A52_09800	Autophagy-related protein. (118 aa)
	PV10_07291	Uncharacterized protein. (191 aa)
	PV10_05856	Uncharacterized protein; Belongs to the peptidase S8 family. (500 aa)
	PV10_06626	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (936 aa)
	PV10_04164	Aminotran_1_2 domain-containing protein. (686 aa)
	PV10_04613	Kinase; Belongs to the inositol phosphokinase (IPK) family. (1291 aa)
	PV10_05089	Uncharacterized protein; Belongs to the actin family. (439 aa)
	PV10_01961	Zn(2)-C6 fungal-type domain-containing protein. (672 aa)
	PV10_01979	Uncharacterized protein. (578 aa)
	PV10_02325	Protein kinase domain-containing protein. (1006 aa)
	PV10_02584	Uncharacterized protein. (836 aa)
	PV10_02861	Uncharacterized protein; Belongs to the actin family. (522 aa)
	PV10_03080	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (741 aa)
	PV10_03385	WD_REPEATS_REGION domain-containing protein. (1435 aa)
	PV10_00387	Mannan endo-1,6-alpha-mannosidase. (461 aa)
	PV10_00704	Aminotran_1_2 domain-containing protein. (508 aa)
	PV10_09046	Myotubularin phosphatase domain-containing protein. (896 aa)
	PV10_08696	Uncharacterized protein. (970 aa)
	PV10_06924	Non-specific serine/threonine protein kinase. (638 aa)
	PV10_07457	Uncharacterized protein; Belongs to the synaptobrevin family. (198 aa)
	PV10_06058	Uncharacterized protein. (1472 aa)
	PV10_03812	Uncharacterized protein. (1662 aa)
	PV10_04182	ATG16 domain-containing protein. (207 aa)
	PV10_04478	Ras-like protein. (217 aa)
	PV10_04736	Uncharacterized protein. (844 aa)
	PV10_04789	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (416 aa)
	PV10_02991	Uncharacterized protein. (165 aa)
	PV10_03115	Uncharacterized protein. (1957 aa)
	PV10_03176	Uncharacterized protein. (1041 aa)
	PV10_00154	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (954 aa)
	PV10_00347	Uncharacterized protein. (269 aa)
	PV10_00401	Uncharacterized protein. (276 aa)
	PV10_00535	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (412 aa)
	PV10_00648	Uncharacterized protein. (219 aa)
	PV10_00867	Uncharacterized protein. (2035 aa)
	PV10_01409	Zn(2)-C6 fungal-type domain-containing protein. (616 aa)
	PV10_08808	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA. (688 aa)
	PV10_08127	CNH domain-containing protein. (1023 aa)
	PV10_08322	Uncharacterized protein. (402 aa)
	PV10_08810	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
	PV10_07834	cAMP-dependent protein kinase type 2; Belongs to the protein kinase superfamily. (424 aa)
	PV10_05362	Uncharacterized protein. (645 aa)
	PV10_05435	Uncharacterized protein. (857 aa)
	PV10_07426	Lipase_3 domain-containing protein. (318 aa)
	PV10_07553	Serine/threonine-protein kinase pef1; Belongs to the protein kinase superfamily. (412 aa)
	PV10_07581	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (662 aa)
	PV10_07811	Protein kinase domain-containing protein. (828 aa)
	PV10_07832	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (645 aa)
	PV10_05822	Uncharacterized protein. (213 aa)
	PV10_07904	Uncharacterized protein. (526 aa)
	PV10_05382	Uncharacterized protein; Belongs to the protein kinase superfamily. (452 aa)
	PV10_06246	Uncharacterized protein. (602 aa)
	PV10_05726	Pep3_Vps18 domain-containing protein. (963 aa)
	PV10_06512	Uncharacterized protein. (506 aa)
	PV10_04058	Mannan endo-1,6-alpha-mannosidase. (464 aa)
	B0A52_10218	Putative Ras-related protein Rab7. (205 aa)
	PV10_03763	Serine/threonine-protein phosphatase. (329 aa)
	PV10_04610	Uncharacterized protein. (644 aa)
	PV10_05052	E3 ubiquitin-protein ligase PEP5. (976 aa)
	PV10_04533	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
	PV10_04869	Phosphatidylinositol 3-kinase VPS34. (936 aa)
	PV10_05010	Uncharacterized protein. (433 aa)
	PV10_05106	Uncharacterized protein. (352 aa)
	PV10_02455	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (312 aa)
	PV10_02642	ATG11 domain-containing protein. (1393 aa)
	PV10_02826	Non-specific serine/threonine protein kinase. (894 aa)
	PV10_02858	Uncharacterized protein. (619 aa)
	B0A52_02850	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
	PV10_03247	Vps8 domain-containing protein. (1539 aa)
	PV10_02708	Aa_trans domain-containing protein. (572 aa)
	PV10_02756	Aa_trans domain-containing protein. (760 aa)
	PV10_08109	Uncharacterized protein. (362 aa)
	PV10_00397	Non-specific serine/threonine protein kinase. (912 aa)
	PV10_08727	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (546 aa)
	PV10_00311	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (399 aa)
	PV10_06869	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2499 aa)
	PV10_07061	Uncharacterized protein. (675 aa)
	B0A52_00300	Uncharacterized protein. (292 aa)
	PV10_01497	G-patch domain-containing protein. (681 aa)
	B0A52_00242	Eukaryotic translation initiation factor 2 subunit alpha. (313 aa)
	PV10_01814	t-SNARE coiled-coil homology domain-containing protein. (232 aa)
	PV10_05566	Mannan endo-1,6-alpha-mannosidase. (456 aa)
	PV10_06009	Autophagy-related protein 3. (371 aa)
	PV10_06270	Uncharacterized protein. (244 aa)
	PV10_06471	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (163 aa)
	PV10_04782	Kinase; Belongs to the inositol phosphokinase (IPK) family. (376 aa)
	PV10_00333	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (515 aa)
	PV10_00437	Uncharacterized protein. (1309 aa)
	PV10_01149	Uncharacterized protein. (318 aa)
	PV10_01158	CNH domain-containing protein. (1183 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_00242	B0A52_00300	A0A0D1ZVP3	A0A0D1ZTZ4	Eukaryotic translation initiation factor 2 subunit alpha.	Uncharacterized protein.	0.509
B0A52_00242	B0A52_02850	A0A0D1ZVP3	A0A0D1ZL36	Eukaryotic translation initiation factor 2 subunit alpha.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.465
B0A52_00242	PV10_00704	A0A0D1ZVP3	A0A0D1X513	Eukaryotic translation initiation factor 2 subunit alpha.	Aminotran_1_2 domain-containing protein.	0.478
B0A52_00242	PV10_02584	A0A0D1ZVP3	A0A0D1WZA5	Eukaryotic translation initiation factor 2 subunit alpha.	Uncharacterized protein.	0.439
B0A52_00242	PV10_03385	A0A0D1ZVP3	A0A0D1X1W7	Eukaryotic translation initiation factor 2 subunit alpha.	WD_REPEATS_REGION domain-containing protein.	0.784
B0A52_00242	PV10_03763	A0A0D1ZVP3	A0A0D1ZF22	Eukaryotic translation initiation factor 2 subunit alpha.	Serine/threonine-protein phosphatase.	0.652
B0A52_00242	PV10_04164	A0A0D1ZVP3	A0A0D1WUH3	Eukaryotic translation initiation factor 2 subunit alpha.	Aminotran_1_2 domain-containing protein.	0.457
B0A52_00242	PV10_06058	A0A0D1ZVP3	A0A0D1XTR3	Eukaryotic translation initiation factor 2 subunit alpha.	Uncharacterized protein.	0.958
B0A52_00242	PV10_06869	A0A0D1ZVP3	A0A0D1ZRU3	Eukaryotic translation initiation factor 2 subunit alpha.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.860
B0A52_00242	PV10_08322	A0A0D1ZVP3	A0A0D1Z423	Eukaryotic translation initiation factor 2 subunit alpha.	Uncharacterized protein.	0.806
B0A52_00300	B0A52_00242	A0A0D1ZTZ4	A0A0D1ZVP3	Uncharacterized protein.	Eukaryotic translation initiation factor 2 subunit alpha.	0.509
B0A52_00300	B0A52_09800	A0A0D1ZTZ4	A0A0D1WJD1	Uncharacterized protein.	Autophagy-related protein.	0.422
B0A52_00300	B0A52_10218	A0A0D1ZTZ4	A0A0D1ZDZ5	Uncharacterized protein.	Putative Ras-related protein Rab7.	0.810
B0A52_00300	PV10_00347	A0A0D1ZTZ4	A0A0D1Y703	Uncharacterized protein.	Uncharacterized protein.	0.413
B0A52_00300	PV10_00704	A0A0D1ZTZ4	A0A0D1X513	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.448
B0A52_00300	PV10_01814	A0A0D1ZTZ4	A0A0D1ZVV4	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.996
B0A52_00300	PV10_02584	A0A0D1ZTZ4	A0A0D1WZA5	Uncharacterized protein.	Uncharacterized protein.	0.990
B0A52_00300	PV10_04164	A0A0D1ZTZ4	A0A0D1WUH3	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.445
B0A52_00300	PV10_04478	A0A0D1ZTZ4	A0A0D1XYC6	Uncharacterized protein.	Ras-like protein.	0.413
B0A52_00300	PV10_04533	A0A0D1ZTZ4	A0A0D1ZHK9	Uncharacterized protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.405