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| | AKB63312.1 | CAAX amino terminal protease family protein. (291 aa) |
| | rps17e | SSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa) |
| | AKB63289.1 | Histone acetyltransferase, ELP3 family. (346 aa) |
| | gatC | Aspartyl-tRNA(Asn) amidotransferase subunit C / Glutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (93 aa) |
| | gatA | Aspartyl-tRNA(Asn) amidotransferase subunit A / Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (475 aa) |
| | gatB | Aspartyl-tRNA(Asn) amidotransferase subunit B / Glutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (495 aa) |
| | AKB63261.1 | tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (364 aa) |
| | AKB63236.1 | Hypothetical protein. (511 aa) |
| | AKB63219.1 | Archaeosine tRNA-ribosyltransferase type 2. (623 aa) |
| | AKB63218.1 | Ribosomal-protein-S18p-alanine acetyltransferase. (200 aa) |
| | rtcA | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (352 aa) |
| | kptA | RNA:NAD 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (182 aa) |
| | AKB63202.1 | Translation elongation factor 1 alpha-related protein. (350 aa) |
| | tgtA | Archaeosine tRNA-ribosyltransferase type 1; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (490 aa) |
| | AKB66516.1 | tRNA dihydrouridine synthase B. (323 aa) |
| | AKB66515.1 | Signal peptidase I. (185 aa) |
| | taw1 | Fe-S OXIDOREDUCTASE Wyeosine biosynthesis; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (341 aa) |
| | prf1 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa) |
| | argS | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (569 aa) |
| | AKB66503.1 | Translation initiation factor IF-2 subunit beta. (68 aa) |
| | AKB66502.1 | Translation initiation factor IF-2 subunit beta. (68 aa) |
| | AKB66501.1 | Translation initiation factor IF-2 subunit beta. (68 aa) |
| | AKB66500.1 | Translation initiation factor IF-2 subunit beta. (86 aa) |
| | sepS | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa) |
| | AKB66473.1 | Hypothetical protein. (204 aa) |
| | AKB66471.1 | Glycyl-tRNA synthetase. (622 aa) |
| | AKB66470.1 | Hypothetical protein. (274 aa) |
| | AKB66460.1 | Transcription factor S. (95 aa) |
| | AKB66451.1 | tRNA-guanine(15) transglycosylase. (145 aa) |
| | pylS | Pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (454 aa) |
| | AKB66410.1 | Fe-S oxidoreductase. (326 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (492 aa) |
| | trpS | Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (495 aa) |
| | eif2b | Eukaryotic translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (202 aa) |
| | rpl10e | LSU ribosomal protein L10e (L16p); Belongs to the universal ribosomal protein uL16 family. (166 aa) |
| | AKB66379.1 | RNA-binding protein YhbY. (86 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (926 aa) |
| | AKB66376.1 | Acetyltransferase (GNAT) family protein. (324 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (269 aa) |
| | AKB66368.1 | tRNA-(G10-N2) dimethyltransferase. (348 aa) |
| | AKB66327.1 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (146 aa) |
| | rtcB | RNA-2',3'-PO4:RNA-5'-OH ligase; Belongs to the RtcB family. (500 aa) |
| | rnp4 | Ribonuclease P protein component 4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (107 aa) |
| | flpA | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa) |
| | AKB66262.1 | S-adenosyl-L-methionine-binding protein. (145 aa) |
| | AKB66252.1 | Hypothetical protein. (196 aa) |
| | AKB66248.1 | Hypothetical protein; Belongs to the LarC family. (396 aa) |
| | lysS-2 | Lysyl-tRNA synthetase (class I); Belongs to the class-I aminoacyl-tRNA synthetase family. (537 aa) |
| | AKB66163.1 | Hypothetical protein. (211 aa) |
| | AKB66162.1 | Hypothetical protein. (134 aa) |
| | gltX | Glutamyl-tRNA synthetase / Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | rpl18e | LSU ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (126 aa) |
| | rpl13 | LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa) |
| | rps9 | SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa) |
| | AKB66115.1 | DNA-directed RNA polymerase subunit K. (37 aa) |
| | rps2 | SSU ribosomal protein SAe (S2p); Belongs to the universal ribosomal protein uS2 family. (246 aa) |
| | tfb | Transcription initiation factor B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa) |
| | AKB66101.1 | tRNA (Guanine37-N1) -methyltransferase. (336 aa) |
| | AKB66075.1 | DNA helicase II. (467 aa) |
| | nop10 | Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (51 aa) |
| | AKB66072.1 | Eukaryotic translation initiation factor 2 alpha subunit. (268 aa) |
| | rps27e | SSU ribosomal protein S27e. (62 aa) |
| | rpl44e | LSU ribosomal protein L44e; Binds to the 23S rRNA. (92 aa) |
| | AKB66063.1 | Hypothetical protein. (779 aa) |
| | AKB66052.1 | Archaeal histone. (70 aa) |
| | AKB66040.1 | tRNA:Cm32/Um32 methyltransferase. (252 aa) |
| | AKB66029.1 | tRNA-dihydrouridine synthase C. (379 aa) |
| | csl4 | Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (316 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa) |
| | AKB66002.1 | O-phosphoseryl-tRNA:Cysteinyl-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa) |
| | AKB65984.1 | Phenylacetic acid degradation protein paaI. (153 aa) |
| | AKB65976.1 | Hypothetical protein. (147 aa) |
| | cysS | Cysteinyl-tRNA synthetase. (473 aa) |
| | lysS | Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa) |
| | AKB65921.1 | Hypothetical protein. (75 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa) |
| | AKB65914.1 | tRNAHis-5'-guanylyltransferase. (243 aa) |
| | AKB65902.1 | Histone acetyltransferase, ELP3 family. (581 aa) |
| | AKB65865.1 | Putative RNA-processing protein. (182 aa) |
| | eif1a-4 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (91 aa) |
| | rps8e | SSU ribosomal protein S8e. (125 aa) |
| | AKB65837.1 | Archaeosine tRNA-ribosyltransferase type 2 short. (227 aa) |
| | hisS | Histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (411 aa) |
| | rps15 | SSU ribosomal protein S13e (S15p). (152 aa) |
| | AKB65804.1 | Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (247 aa) |
| | dys-2 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (317 aa) |
| | AKB65756.1 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (286 aa) |
| | rpl4 | LSU ribosomal protein L1e (L4p); Forms part of the polypeptide exit tunnel. (253 aa) |
| | rpl23 | LSU ribosomal protein L23Ae (L23p); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa) |
| | rpl2 | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa) |
| | rps19p | SSU ribosomal protein S15e (S19p); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl22 | LSU ribosomal protein L17e (L22p); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (151 aa) |
| | rps3 | SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (307 aa) |
| | rpl29 | LSU ribosomal protein L35e (L29p); Belongs to the universal ribosomal protein uL29 family. (67 aa) |
| | rnp1 | Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (106 aa) |
| | rps17 | SSU ribosomal protein S11e (S17p); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (109 aa) |
| | rpl14 | LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rpl24 | LSU ribosomal protein L26e (L24p); Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa) |
| | rps4e | SSU ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (235 aa) |
| | rpl5 | LSU ribosomal protein L11e (L5p); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (165 aa) |
| | rps14 | SSU ribosomal protein S29e (S14p); Binds 16S rRNA, required for the assembly of 30S particles. (50 aa) |
| | rps8 | SSU ribosomal protein S15Ae (S8p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6 | LSU ribosomal protein L9e (L6p); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (176 aa) |
| | rpl32e | LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (145 aa) |
| | rpl19e | LSU ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa) |
| | rpl18 | LSU ribosomal protein L5e (L18p); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (174 aa) |
| | rps5 | SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy. (209 aa) |
| | rpl30 | LSU ribosomal protein L7e (L30p). (153 aa) |
| | rpl15 | LSU ribosomal protein L27Ae (L15p); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (140 aa) |
| | truB | tRNA pseudouridine 55 synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa) |
| | rps13 | SSU ribosomal protein S18e (S13p); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (152 aa) |
| | rps4 | SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (219 aa) |
| | rps11 | SSU ribosomal protein S14e (S11p); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (126 aa) |
| | AKB65722.1 | DNA-directed RNA polymerase subunit D. (243 aa) |
| | AKB65717.1 | [NiFe] hydrogenase metallocenter assembly protein HypC. (97 aa) |
| | AKB65706.1 | KEOPS complex Cgi121-like subunit. (174 aa) |
| | AKB65703.1 | (dimethylallyl)adenosine tRNA methylthiotransferase. (435 aa) |
| | tbp-3 | TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (170 aa) |
| | AKB65695.1 | Hypothetical protein. (276 aa) |
| | AKB65633.1 | Hypothetical protein. (98 aa) |
| | AKB65631.1 | Hypothetical protein. (127 aa) |
| | rps10 | SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Translation elongation factor 1 alpha subunit; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa) |
| | fusA | Translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (716 aa) |
| | rps7 | SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa) |
| | rps12 | SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | nusA | Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (141 aa) |
| | rpl30e | LSU ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (407 aa) |
| | AKB65620.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa) |
| | AKB65619.1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa) |
| | AKB65618.1 | DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family. (531 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (107 aa) |
| | AKB65605.1 | Hypothetical protein. (347 aa) |
| | rlmE | Cell division protein FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (268 aa) |
| | gatD | Glutamyl-tRNA(Gln) amidotransferase asparaginase subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (425 aa) |
| | AKB65582.1 | [NiFe] hydrogenase metallocenter assembly protein HypC. (86 aa) |
| | AKB65581.1 | [NiFe] hydrogenase metallocenter assembly protein HypD. (373 aa) |
| | hypA | [NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (137 aa) |
| | AKB65578.1 | [NiFe] hydrogenase metallocenter assembly protein HypE. (348 aa) |
| | eif1a-3 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (106 aa) |
| | eif1a-2 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (59 aa) |
| | AKB65511.1 | Putative snRNP Sm-like protein, Archaeal. (74 aa) |
| | AKB65510.1 | Hypothetical protein. (141 aa) |
| | rps6e | SSU ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (136 aa) |
| | infB | Translation initiation factor 2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (577 aa) |
| | rpl24e | LSU ribosomal protein L24e; Binds to the 23S rRNA. (62 aa) |
| | rps28e | SSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa) |
| | rpl7ae | LSU ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa) |
| | ef1b | Translation elongation factor 1 beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | thiI | tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (405 aa) |
| | trm1 | tRNA N2,N2-dimethyl(Guanine26-N2)-methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (382 aa) |
| | trmY | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (211 aa) |
| | pus10 | tRNA pseudouridine 55 synthase Archaea; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (431 aa) |
| | rpl21e | LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | AKB65363.1 | DNA-directed RNA polymerase subunit F. (117 aa) |
| | AKB65361.1 | Putative ribosomal RNA small subunit methyltransferase A; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (209 aa) |
| | AKB65312.1 | DNA helicase related protein. (1898 aa) |
| | rpl15e | LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa) |
| | rnp3 | Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (239 aa) |
| | rnp2 | Ribonuclease P protein component 2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (116 aa) |
| | rpl37ae | LSU ribosomal protein L37Ae; Binds to the 23S rRNA. (94 aa) |
| | rpoP | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (45 aa) |
| | AKB65277.1 | Imp4 family protein. (124 aa) |
| | AKB65276.1 | Hypothetical protein. (82 aa) |
| | AKB65244.1 | GCN5-related N-acetyltransferase. (160 aa) |
| | AKB65241.1 | GCN5-related N-acetyltransferase. (51 aa) |
| | AKB65240.1 | GCN5-related N-acetyltransferase. (171 aa) |
| | AKB65209.1 | Hypothetical protein. (351 aa) |
| | AKB65134.1 | OB-fold nucleic acid binding domain protein. (346 aa) |
| | AKB65127.1 | N-type ATP pyrophosphatase superfamily; TilS and TtcA-like. (302 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain. (545 aa) |
| | AKB64977.1 | Metallo-beta-lactamase family protein. (456 aa) |
| | AKB64964.1 | Metal dependent hydrolase. (251 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1058 aa) |
| | AKB64875.1 | Hypothetical protein. (636 aa) |
| | AKB64810.1 | Ribosome biogenesis protein TSR3; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (173 aa) |
| | AKB64790.1 | Putative oxidoreductase/HEAT repeat-containing protein. (457 aa) |
| | taw2 | tRNA methylase Trm12p Wyeosine biosynthesis; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (343 aa) |
| | AKB64601.1 | tRNA (guanine(37)-N1)-methyltransferase Trm5a. (282 aa) |
| | AKB64590.1 | Hypothetical protein. (107 aa) |
| | AKB64589.1 | Iron-sulfur cluster-binding protein. (287 aa) |
| | thrS | Threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (634 aa) |
| | AKB64575.1 | CAAX amino terminal protease family. (281 aa) |
| | eif1a | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (60 aa) |
| | gatE | Glutamyl-tRNA(Gln) amidotransferase transferase subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (633 aa) |
| | aspS | Aspartyl-tRNA synthetase / Aspartyl-tRNA(Asn) synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (444 aa) |
| | AKB64443.1 | Phosphoserine phosphatase; Belongs to the UPF0237 family. (92 aa) |
| | AKB64440.1 | tRNA cytosine methylase Pos56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (177 aa) |
| | AKB64415.1 | Peptidyl-tRNA hydrolase, archaeal type. (91 aa) |
| | truD | tRNA pseudouridine 13 synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (438 aa) |
| | rps3ae | SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (204 aa) |
| | AKB64265.1 | Gly-tRNA(Ala) deacylase. (270 aa) |
| | leuS | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (966 aa) |
| | dys | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (345 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (305 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (869 aa) |
| | AKB64158.1 | Putative snRNP Sm-like protein; Belongs to the snRNP Sm proteins family. (72 aa) |
| | rpl37e | LSU ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (56 aa) |
| | AKB64146.1 | Hypothetical protein. (258 aa) |
| | AKB64073.1 | RNase L inhibitor. (588 aa) |
| | tiaS | OB-fold nucleic acid binding domain protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (449 aa) |
| | cca | tRNA nucleotidyltransferase, archaeal type; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa) |
| | AKB64011.1 | Phycocyanin alpha phycocyanobilin lyase. (452 aa) |
| | AKB63999.1 | Hypothetical protein. (226 aa) |
| | AKB63998.1 | Hypothetical protein. (1142 aa) |
| | endA | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (350 aa) |
| | eif2g | Eukaryotic translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa) |
| | AKB63909.1 | DNA-directed RNA polymerase subunit E'. (190 aa) |
| | rps24e | SSU ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (101 aa) |
| | rps27ae | SSU ribosomal protein S27Ae; Belongs to the eukaryotic ribosomal protein eS31 family. (49 aa) |
| | AKB63903.1 | YgjD/Kae1/Qri7 family, required for N6-threonylcarbamoyl adenosine t(6)A37 modification in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belo [...] (562 aa) |
| | AKB63892.1 | Hypothetical protein. (345 aa) |
| | tfe | Archaeal transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexe [...] (164 aa) |
| | AKB63805.1 | tRNA-guanine(15) transglycosylase. (161 aa) |
| | proS | Prolyl-tRNA synthetase, archaeal/eukaryal type; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | AKB63737.1 | Hypothetical protein. (272 aa) |
| | rps19e | SSU ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (149 aa) |
| | rpl39e | LSU ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (47 aa) |
| | rpl31e | LSU ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (93 aa) |
| | eif6 | Eukaryotic translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (215 aa) |
| | rpl18a | LSU ribosomal protein L18Ae. (58 aa) |
| | AKB63643.1 | Translation initiation factor SUI1-related protein; Belongs to the SUI1 family. (102 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (711 aa) |
| | eif5a | Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa) |
| | rpl40e | LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa) |
| | spt5 | Putative transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa) |
| | rpl11 | LSU ribosomal protein L12e (L11p); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa) |
| | rpl1 | LSU ribosomal protein L10Ae (L1p); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) |
| | rpl10 | LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (347 aa) |
| | rpl12 | LSU ribosomal protein L12a (P1/P2); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (104 aa) |
| | AKB63477.1 | Iron-sulfur cluster-binding protein. (247 aa) |
| | tbp-2 | TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa) |
| | tbp | TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa) |
| | AKB63448.1 | GTP-binding protein RBG1/RBG2. (364 aa) |
| | AKB63349.1 | CAAX amino terminal protease family protein. (285 aa) |
| | AKB63319.1 | CAAX amino terminal protease family protein. (465 aa) |
