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| | cdhC | CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (469 aa) |
| | cdhD | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. (436 aa) |
| | cdhE | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (470 aa) |
| | nifH | Nitrogenase (molybdenum-iron) reductase and maturation protein NifH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (273 aa) |
| | AKB63516.1 | CoB--CoM heterodisulfide reductase subunit C. (161 aa) |
| | AKB63515.1 | CoB--CoM heterodisulfide reductase subunit B. (300 aa) |
| | AKB63427.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (339 aa) |
| | AKB63424.1 | Methanol methyltransferase corrinoid protein. (258 aa) |
| | mtd | F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa) |
| | AKB63269.1 | Methyl coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (570 aa) |
| | AKB63268.1 | Methyl coenzyme M reductase gamma subunit. (227 aa) |
| | AKB63267.1 | Methyl coenzyme M reductase operon protein C. (205 aa) |
| | AKB63266.1 | Methyl coenzyme M reductase operon protein D. (170 aa) |
| | AKB64465.1 | Formylmethanofuran dehydrogenase subunit B. (414 aa) |
| | AKB63265.1 | Methyl coenzyme M reductase beta subunit. (434 aa) |
| | AKB64466.1 | Tungsten-containing formylmethanofuran dehydrogenase 2 subunit G. (150 aa) |
| | AKB64468.1 | CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (793 aa) |
| | AKB64542.1 | Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa) |
| | AKB64543.1 | Monomethylamine methyltransferase corrinoid protein. (218 aa) |
| | AKB64942.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa) |
| | AKB64943.1 | Dimethylamine methyltransferase corrinoid protein. (214 aa) |
| | AKB65098.1 | 5,10-methylenetetrahydromethanopterin reductase. (266 aa) |
| | mch | N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (321 aa) |
| | fpoH | FPO subunit H; FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (347 aa) |
| | AKB65468.1 | Methylthiol:coenzyme M methyltransferase corrinoid protein. (275 aa) |
| | AKB65640.1 | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A. (182 aa) |
| | cdhA-2 | CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (806 aa) |
| | cdhB-2 | CO dehydrogenase/acetyl-CoA synthase subunit epsilon, CO dehydrogenase subcomplex; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation. (170 aa) |
| | cdhC-2 | CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (460 aa) |
| | AKB65796.1 | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit. (436 aa) |
| | cdhE-2 | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (470 aa) |
| | AKB65830.1 | Dimethylamine methyltransferase corrinoid protein. (216 aa) |
| | AKB65831.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (468 aa) |
| | AKB65832.1 | Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (495 aa) |
| | AKB65895.1 | Formylmethanofuran dehydrogenase (tungsten) subunit D. (127 aa) |
| | AKB65896.1 | Formylmethanofuran dehydrogenase subunit B. (450 aa) |
| | AKB65898.1 | Formylmethanofuran dehydrogenase subunit C. (252 aa) |
| | AKB66032.1 | Polyprenyl synthetase. (207 aa) |
| | AKB66033.1 | Polyprenyl synthetase. (211 aa) |
| | AKB66034.1 | CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D. (409 aa) |
| | AKB66035.1 | CoB--CoM heterodisulfide reductase 2 subunit E. (241 aa) |
| | AKB66176.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa) |
| | AKB66180.1 | Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (495 aa) |
| | AKB66181.1 | Dimethylamine methyltransferase corrinoid protein. (167 aa) |
| | AKB66218.1 | Methanol methyltransferase corrinoid protein. (258 aa) |
| | AKB66295.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit B. (433 aa) |
| | AKB66296.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit D. (129 aa) |
| | AKB66297.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit C. (288 aa) |
| | mtrE | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (304 aa) |
| | mtrD | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (250 aa) |
| | mtrC | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (267 aa) |
| | mtrB | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (108 aa) |
| | mtrA | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (240 aa) |
| | mtrF | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa) |
| | mtrG | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa) |
| | mtrH | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (316 aa) |
| | AKB66421.1 | Methylcobalamin:coenzyme M methyltransferase, methylamine-specific. (339 aa) |
| | AKB66423.1 | Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa) |
| | ftr | Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (297 aa) |
| | AKB64464.1 | Formylmethanofuran dehydrogenase subunit D. (132 aa) |
| | AKB64323.1 | Methanol methyltransferase corrinoid protein. (255 aa) |
| | AKB64321.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (339 aa) |
| | AKB64111.1 | CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (805 aa) |
| | AKB64110.1 | CoB--CoM heterodisulfide reductase subunit C. (236 aa) |
| | AKB64109.1 | CoB--CoM heterodisulfide reductase subunit B. (296 aa) |
| | AKB64106.1 | CoB--CoM heterodisulfide reductase subunit B. (83 aa) |
| | AKB64099.1 | CoB--CoM heterodisulfide reductase subunit B. (100 aa) |
| | AKB64095.1 | CoB--CoM heterodisulfide reductase subunit B. (100 aa) |
| | AKB64092.1 | CoB--CoM heterodisulfide reductase subunit B. (100 aa) |
| | cbiA | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (498 aa) |
| | AKB63988.1 | Nitrogenase reductase-like protein. (265 aa) |
| | AKB63987.1 | Nitrogenase-related protein. (370 aa) |
| | AKB63986.1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase. (483 aa) |
| | cbiX | Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (130 aa) |
| | mer | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (328 aa) |
| | cdhA | CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (807 aa) |
| | cdhB | CO dehydrogenase/acetyl-CoA synthase subunit epsilon, CO dehydrogenase subcomplex; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation. (170 aa) |
