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| | engB | Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (216 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | spoU | tRNA (guanosine-2'-O-)-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (230 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa) |
| | rpmB | Similar to Escherichia coli 50S ribosomal protein L28 RpmB SW:RL28_ECOLI (P02428) (77 aa) fasta scores: E(): 1.1e-32, 92.2% id in 77 aa; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | rpmG | 50S ribosomal protein L33; Similar to Escherichia coli and Salmonella typhimurium 50S ribosomal protein L33 SW:RL33_ECOLI (P02436) (54 aa) fasta scores: E(): 1.7e-21, 96.3% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | secB | Protein-export protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (158 aa) |
| | YPO0072 | Similar to Escherichia coli Ada regulatory protein of the adaptive response, involved in DNA repair and global regulation SW:ADA_ECOLI (P06134) (354 aa) fasta scores: E(): 0, 52.8% id in 345 aa. (354 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (71 aa) |
| | greB | Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. (171 aa) |
| | ppiA | Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (189 aa) |
| | rpsl | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | far | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (702 aa) |
| | tufA | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | nusE | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | eryA | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (201 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | 50S ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | eryB | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (110 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | Similar to Escherichia coli 50S ribosomal protein L29 RpmC SW:RL29_ECOLI (P02429) (63 aa) fasta scores: E(): 1.3e-20, 93.7% id in 63 aa; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | neaA | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rplX | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa) |
| | rpmD | Similar to Escherichia coli 50S ribosomal protein L30 RpmD SW:RL30_ECOLI (P02430) (58 aa) fasta scores: E(): 1.5e-22, 86.2% id in 58 aa. (59 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | prlA | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa) |
| | rpmJ | Similar to Escherichia coli 50S ribosomal protein L36 RpmJ SW:RL36_ECOLI (P21194) (38 aa) fasta scores: E(): 2.1e-15, 94.7% id in 38 aa; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | ramA | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa) |
| | rplQ | Similar to Escherichia coli 50S ribosomal protein L17 RplQ SW:RL17_ECOLI (P02416) (127 aa) fasta scores: E(): 0, 94.5% id in 127 aa. (129 aa) |
| | YPO0236 | MerR-family transcriptional regulator; Similar to Escherichia coli zinc responsive regulator of the zinc/cadmium expoter, ZntR SW:ZNTR_ECOLI (P36676) (141 aa) fasta scores: E(): 0, 69.6% id in 135 aa. (141 aa) |
| | YPO0237 | Similar to Escherichia coli hypothetical protein YhdL SW:YHDL_ECOLI (P36675) (72 aa) fasta scores: E(): 5.5e-17, 69.4% id in 62 aa. (66 aa) |
| | YPO0290 | Similar to Deinococcus radiodurans hypothetical protein DR2218 TR:Q9RSA8 (EMBL:AE002054) (353 aa) fasta scores: E(): 6.2e-23, 35.2% id in 338 aa. (359 aa) |
| | YPO0353 | Conserved hypothetical protein; Similar to many proteins of undefined function e.g. Escherichia coli hypothetical protein YjeK SW:YJEK_ECOLI (P39280) (342 aa) fasta scores: E(): 0, 71.3% id in 341 aa. Also similar to several L-lysine 2,3-aminomutases e.g. from Clostridium subterminale KamA TR:Q9XBQ8 (EMBL:AF159146) (416 aa) fasta scores: E(): 0, 34.6% id in 324 aa. (342 aa) |
| | b4147 | Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | b4155 | Putative lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | b4162 | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. (844 aa) |
| | rlmB | Putative methylase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily. (246 aa) |
| | b4375 | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | rob | Similar to Escherichia coli right origin-binding protein Rob SW:ROB_ECOLI (P27292) (289 aa) fasta scores: E(): 0, 68.2% id in 289 aa, and to Bacillus halodurans possible transcriptional regulator BH3634 TR:Q9K6U1 (EMBL:AP001519) (300 aa) fasta scores: E(): 1.7e-19, 30.5% id in 311 aa. (288 aa) |
| | b0023 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | b0026 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa) |
| | rluA | Ribosomal large subunit pseudouridine synthase A; Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs. (206 aa) |
| | azi | Preprotein translocase SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (904 aa) |
| | alt | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (612 aa) |
| | rpsU | 30S ribosomal protein S21; Identical to Escherichia coli and Salmonella typhimurium 30S ribosomal protein S21 RpsU SW:RS21_ECOLI (P02379) (70 aa) fasta scores: E(): 2.3e-27, 100.0% id in 70 aa, and to Buchnera aphidicola (subsp Acyrthosiphon pisum) 30S ribosomal protein S21 RpsU TR:BAB12780 (EMBL:AP001118) (71 aa) fasta scores: E(): 1e-25, 90.1% id in 71 aa; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | cca | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (412 aa) |
| | asuD | Similar to Escherichia coli lysyl-tRNA synthetase LysS SW:SYK1_ECOLI (P13030) (504 aa) fasta scores: E(): 0,85.9% id in 504 aa, and to Haemophilus influenzae lysyl-tRNA synthetase LysS SW:SYK_HAEIN (P43825) (502 aa) fasta scores: E(): 0, 68.5% id in 504 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (366 aa) |
| | rpsB | Similar to Escherichia coli 30S ribosomal protein S2 RpsB SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 0,93.8% id in 240 aa; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (285 aa) |
| | b0172 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | YPO1066 | Similar to Escherichia coli hypothetical protein YaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0,65.2% id in 135 aa, and to Pseudomonas putida hypothetical protein SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 8.6e-31, 65.2% id in 135 aa, and to Streptomyces coelicolor hypothetical protein SCD95A.11 TR:Q9KXW3 (EMBL:AL357432) (145 aa) fasta scores: E(): 7.4e-13, 41.5% id in 135 aa. (138 aa) |
| | drpA | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | b2620 | SsrA-binding protein (small protein B); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...] (160 aa) |
| | rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | YPO1284 | Putative elongation factor P; C-terminal region is similar to similar to Synechococcus sp elongation factor P Efp SW:EFP_SYNP7 (Q54760) (185 aa) fasta scores: E(): 3.4e-17, 31.9% id in 188 aa. Similar to the C-terminal region of Escherichia coli hypothetical protein YeiP SW:YEIP_ECOLI (P33028) (275 aa) fasta scores: E(): 0, 78.0% id in 205 aa. Possible alternative translational start sites. (190 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | rpsA | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | cspB | Cold shock-like protein; Similar to Yersinia enterocolitica cold shock-like protein CspB SW:CSPB_YEREN (O85593) (70 aa) fasta scores: E(): 3e-12, 51.4% id in 70 aa, and to Escherichia coli cold shock-like protein CspE SW:CSPE_ECOLI (P36997) (68 aa) fasta scores: E(): 4.2e-12, 54.7% id in 64 aa. (69 aa) |
| | asnS | Similar to Escherichia coli asparaginyl-tRNA synthetase AsnS SW:SYN_ECOLI (P17242) (465 aa) fasta scores: E(): 0, 87.3% id in 465 aa, and to Haemophilus influenzae asparaginyl-tRNA synthetase AsnS SW:SYN_HAEIN (P43829) (477 aa) fasta scores: E(): 0, 79.5% id in 464 aa. (466 aa) |
| | ybiT | Similar to Escherichia coli hypothetical ABC transporter ATP-binding protein YbiT SW:YBIT_ECOLI (P75790) (530 aa) fasta scores: E(): 0, 87.0% id in 529 aa, and to Vibrio cholerae ABC transporter, ATP-binding protein VC1520 TR:Q9KRW4 (EMBL:AE004230) (530 aa) fasta scores: E(): 0,75.6% id in 529 aa. (531 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (675 aa) |
| | YPO1551 | Putative exported protein; Similar to Escherichia coli hypothetical protein YeeZ SW:YEEZ_ECOLI (P76370) (274 aa) fasta scores: E(): 0,65.7% id in 274 aa, and to Deinococcus radiodurans conserved hypothetical protein DR0832 TR:Q9RW37 (EMBL:AE001937) (290 aa) fasta scores: E(): 4.4e-31, 40.4% id in 267 aa. (275 aa) |
| | ams | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1221 aa) |
| | rluC | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. (320 aa) |
| | YPO1594 | Similar to Escherichia coli hypothetical protein Yced or G30K SW:YCED_ECOLI (P14189) (173 aa) fasta scores: E(): 0, 79.7% id in 172 aa, and to Haemophilus influenzae hypothetical protein HI0159 SW:YCED_HAEIN (P43790) (174 aa) fasta scores: E(): 0, 55.5% id in 173 aa. (174 aa) |
| | rpmF | 50S ribosomal protein L32; Similar to Escherichia coli, and Salmonella typhimurium 50S ribosomal protein L32 SW:RL32_ECOLI (P02435) (56 aa) fasta scores: E(): 3.4e-20, 90.7% id in 54 aa, and to Haemophilus influenzae 50S ribosomal protein L32 RpmF or Rpl32 or Hi0158 SW:RL32_HAEIN (P44368) (55 aa) fasta scores: E(): 4.3e-19, 83.0% id in 53 aa; Belongs to the bacterial ribosomal protein bL32 family. (55 aa) |
| | dbpA | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (460 aa) |
| | argS | Similar to Escherichia coli arginyl-tRNA synthetase ArgS SW:SYR_ECOLI (P11875) (577 aa) fasta scores: E(): 0,82.8% id in 577 aa, and to Vibrio cholerae arginyl-tRNA synthetase VC2074 TR:Q9KQC6 (EMBL:AE004281) (599 aa) fasta scores: E(): 0, 71.4% id in 577 aa. (576 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa) |
| | YPO2055 | Similar to Escherichia coli hypothetical protein YebC SW:YEBC_ECOLI (P24237) (246 aa) fasta scores: E(): 0,84.6% id in 247 aa, and to Haemophilus influenzae hypothetical protein HI0315 SW:YEBC_HAEIN (P44634) (246 aa) fasta scores: E(): 0, 73.3% id in 247 aa. (247 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (373 aa) |
| | YPO2228 | Translation initiation factor SUI1 family protein; Similar to Escherichia coli hypothetical protein YciH SW:YCIH_ECOLI (P08245) (108 aa) fasta scores: E(): 1.3e-30, 80.6% id in 108 aa, and to Salmonella typhimurium hypothetical protein YciH SW:YCIH_SALTY (P20770) (108 aa) fasta scores: E(): 1e-29, 78.7% id in 108 aa; Similar to Escherichia coli protein YciH SW:YCIH_ECOLI (P08245) (108 aa) fasta scores: E(): 1.3e-30,80.6% id in 108 aa. (108 aa) |
| | rnb | Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. (644 aa) |
| | hrpA | Similar to Escherichia coli ATP-dependent helicase HrpA SW:HRPA_ECOLI (P43329) (1281 aa) fasta scores: E(): 0,81.9% id in 1280 aa, and to Vibrio cholerae ATP-dependent helicase HrpA TR:Q9KS77 (EMBL:AE004217) (1309 aa) fasta scores: E(): 0, 70.7% id in 1278 aa. (1280 aa) |
| | YPO2337 | Putative regulatory protein; Similar to Clostridium difficile transcriptional activator TR:AAG15273 (EMBL:AF093568) (272 aa) fasta scores: E(): 0.00036, 21.8% id in 239 aa. N-terminal region is similar to Rhizobium meliloti heavy metal dependent transcription regulator HmrR SW:HMRR_RHIME (Q9X5X4) (147 aa) fasta scores: E(): 0.099, 28.0% id in 125 aa. (279 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | rnt | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (215 aa) |
| | pheT | Similar to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_ECOLI (P07395) (795 aa) fasta scores: E(): 0, 83.4% id in 795 aa, and to Haemophilus influenzae phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_HAEIN (P43820) (795 aa) fasta scores: E(): 0, 64.7% id in 795 aa; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | pheS | Similar to Escherichia coli phenylalanyl-tRNA synthetase alpha chain PheS SW:SYFA_ECOLI (P08312) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Vibrio cholerae phenylalanyl-tRNA synthetase alpha chain PheS TR:Q9KSN7 (EMBL:AE004202) (327 aa) fasta scores: E(): 0,76.1% id in 327 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | pdzA | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | rpmI | Similar to Escherichia coli 50S ribosomal protein L35 RpmI SW:RL35_ECOLI (P07085) (64 aa) fasta scores: E(): 1.8e-25, 89.1% id in 64 aa, and to Haemophilus influenzae 50S ribosomal protein L35 RpmI SW:RL35_HAEIN (P45519) (64 aa) fasta scores: E(): 1.2e-21, 81.3% id in 64 aa; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | fit | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (183 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (642 aa) |
| | YPO2434 | Similar to Caulobacter crescentus hypothetical protein CC0128 TR:Q9ABU2 (EMBL:AE005687) (66 aa) fasta scores: E(): 6.5e-05, 38.983% id in 59 aa, and to the C-terminal region of Rhizobium loti hypothetical protein MLL6859 TR:BAB53070 (EMBL:AP003010) (109 aa) fasta scores: E(): 0.0025, 34.783% id in 69 aa. (70 aa) |
| | rlmH | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa) |
| | rsfS | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa) |
| | leuS | Similar to Escherichia coli leucyl-tRNA synthetase LeuS SW:SYL_ECOLI (P07813) (860 aa) fasta scores: E(): 0,84.8% id in 860 aa, and to Vibrio cholerae leucyl-tRNA synthetase VC0956 TR:Q9KTE6 (EMBL:AE004177) (894 aa) fasta scores: E(): 0, 74.5% id in 858 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | YPO2611 | Similar to Escherichia coli hypothetical protein YbeL SW:YBEL_ECOLI (P46129) (160 aa) fasta scores: E(): 0,78.8% id in 160 aa, and to Vibrio cholerae hypothetical protein VC0957 TR:Q9KTE5 (EMBL:AE004177) (156 aa) fasta scores: E(): 6.8e-19, 36.3% id in 160 aa. (160 aa) |
| | glnS | Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS SW:SYQ_ECOLI (P00962) (553 aa) fasta scores: E(): 0, 87.2% id in 549 aa, and to Vibrio cholerae glutaminyl-tRNA synthetase GlnS TR:Q9KTA6 (EMBL:AE004181) (556 aa) fasta scores: E(): 0, 81.1% id in 551 aa. (555 aa) |
| | cspB-2 | Similar to Escherichia coli plasmid (ColE1) mobilization protein MbeD SW:MBED_ECOLI (P13660) (77 aa) fasta scores: E(): 0.31, 28.4% id in 67 aa, and to Escherichia coli plasmid (pLG13) mobilization protein MobD TR:AAG18130 (EMBL:AF251289) (77 aa) fasta scores: E(): 0.18, 28.4% id in 67 aa. This CDS appears to be disrupted by the insertion of the downstream IS285 element. The insertion occurred near the C-terminus. It is not clear whether this insertion affects the function of the protein. (70 aa) |
| | rbaB | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (441 aa) |
| | YPO2749 | Similar to Escherichia coli hypothetical protein YfcN SW:YFCN_ECOLI (P77458) (183 aa) fasta scores: E(): 0,71.0% id in 176 aa, and to Vibrio cholerae hypothetical protein VC2119 TR:Q9KQ82 (EMBL:AE004285) (186 aa) fasta scores: E(): 0, 58.1% id in 167 aa; Belongs to the UPF0115 family. (176 aa) |
| | prmB | Conserved hypothetical protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (310 aa) |
| | yfgM | Putative membrane protein; Similar to Escherichia coli hypothetical protein YfgM SW:YFGM_ECOLI (P76576) (206 aa) fasta scores: E(): 0,56.7% id in 210 aa, and to Vibrio cholerae hypothetical protein VC0761 vc0761 TR:Q9KTW9 (EMBL:AE004161) (204 aa) fasta scores: E(): 4e-22, 39.6% id in 212 aa. (211 aa) |
| | hisS | Similar to Escherichia coli histidyl-tRNA synthetase HisS SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 0,82.0% id in 423 aa, and to Salmonella typhimurium histidyl-tRNA synthetase HisS SW:SYH_SALTY (O52765) (423 aa) fasta scores: E(): 0, 82.0% id in 423 aa. (424 aa) |
| | suhB | Putative inositol monophosphatase family protein; Similar to Lycopersicon esculentum myo-inositol monophosphatase IMP1 SW:MYO1_LYCES (P54926) (273 aa) fasta scores: E(): 2.5e-29, 35.7% id in 263 aa, and to Escherichia coli extragenic suppressor protein SuhB TR:BAA16435 (EMBL:M34828) (267 aa) fasta scores: E(): 0,83.9% id in 267 aa. (267 aa) |
| | YPO3010 | Hypothetical protein; Weakly similar to the N-terminal and central regions of the previously sequenced Yersinia pestis outer membrane protein YopM or Yop48 SW:YOPM_YERPE (P17778) (367 aa) fasta scores: E(): 0.00012, 29.9% id in 177 aa, and to phage Gifsy-1 leucine-rich repeat protein GogB TR:Q9MBM1 (EMBL:AF254761) (489 aa) fasta scores: E(): 1.4e-19, 36.9% id in 360 aa. (410 aa) |
| | tmcA | Putative acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (699 aa) |
| | cysS | Similar to Escherichia coli cysteinyl-tRNA synthetase CysS SW:SYC_ECOLI (P21888) (461 aa) fasta scores: E(): 0, 83.9% id in 461 aa, and to Vibrio cholerae cysteinyl-tRNA synthetase CysS or Vc1848 SW:SYC_VIBCH (Q9KQZ9) (459 aa) fasta scores: E(): 0, 75.5% id in 461 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | ppiB | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa) |
| | ykgM | Putative ribosomal protein; Similar to Escherichia coli O157:H7 putative ribosomal protein YkgM TR:AAG54622 (EMBL:AE005206) (87 aa) fasta scores: E(): 4.1e-24, 69.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L31P family Vc0878 TR:Q9KTM4 (EMBL:AE004172) (85 aa) fasta scores: E(): 1.4e-20, 62.5% id in 80 aa; Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily. (86 aa) |
| | rpmJ2 | Similar to Vibrio cholerae ribosomal putative protein L36 Vc0879 TR:Q9KTM3 (EMBL:AE004172) (41 aa) fasta scores: E(): 8.8e-16, 87.5% id in 40 aa, and to Neisseria meningitidis (serogroup A) putative 50S ribosomal protein L36 Rpmj2 or Nma1137 or Nmb0941 TR:Q9JQV0 (EMBL:AL162755) (41 aa) fasta scores: E(): 7.6e-14, 82.5% id in 40 aa; Belongs to the bacterial ribosomal protein bL36 family. (47 aa) |
| | tig | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (434 aa) |
| | nusB | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (138 aa) |
| | secF | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa) |
| | secD | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (615 aa) |
| | yajC | Putative membrane protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (111 aa) |
| | yfiF | Similar to Escherichia coli hypothetical tRNA/rRNA methyltransferase YfiF SW:YFIF_ECOLI (P33635) (345 aa) fasta scores: E(): 0, 60.1% id in 388 aa, and to Haemophilus influenzae hypothetical tRNA/rRNA methyltransferase Hi0424 SW:YFIF_HAEIN (P44703) (351 aa) fasta scores: E(): 6.8e-33, 34.8% id in 359 aa. This CDS contains a large insertion at its N-terminal end relative to E. coli; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (388 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. (325 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (246 aa) |
| | rimM | 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (182 aa) |
| | rpsP | Similar to Escherichia coli 30S ribosomal protein S16 RpsP SW:RS16_ECOLI (P02372) (82 aa) fasta scores: E(): 5.4e-26, 79.3% id in 82 aa, and to Salmonella typhimurium 30S ribosomal protein S16 RpsP SW:RS16_SALTY (P36242) (82 aa) fasta scores: E(): 8e-27, 81.7% id in 82 aa; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (453 aa) |
| | YPO3336 | Similar to Escherichia coli hypothetical protein YfbH SW:YBFH_ECOLI () (105 aa) fasta scores: E(): 0.74,23.8% id in 105 aa. (101 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (261 aa) |
| | hrpB | Similar to Rhizobium meliloti helicase HelO TR:Q52902 (EMBL:U49051) (821 aa) fasta scores: E(): 0,43.1% id in 824 aa, and to Escherichia coli ATP-dependent helicase HrpB SW:HRPB_ECOLI (P37024) (809 aa) fasta scores: E(): 0, 65.6% id in 816 aa. (828 aa) |
| | yadB | Putative glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (321 aa) |
| | pcnB | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (440 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (965 aa) |
| | csdA | Cold-shock dead-box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (664 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (705 aa) |
| | rpsO | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | p35 | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (324 aa) |
| | p15B | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (136 aa) |
| | infB | Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (884 aa) |
| | nusA | N utilization substance protein A; Participates in both transcription termination and antitermination. (495 aa) |
| | rimP | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (152 aa) |
| | secG | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (111 aa) |
| | greA | Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (158 aa) |
| | obg | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa) |
| | rpmA | Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 5e-31, 94.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L27 Vc0436 TR:Q9KUS9 (EMBL:AE004131) (86 aa) fasta scores: E(): 1.2e-29, 91.6% id in 83 aa; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (175 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (150 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | priB | Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (106 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (130 aa) |
| | rpsI | Similar to Escherichia coli 30S ribosomal protein S9 RpsI SW:RS9_ECOLI (P02363) (129 aa) fasta scores: E(): 0,92.2% id in 129 aa, and to Vibrio cholerae ribosomal protein S9 Vc0571 TR:Q9KUF0 (EMBL:AE004142) (130 aa) fasta scores: E(): 0, 86.9% id in 130 aa; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | YPO3691 | Similar to Escherichia coli hypothetical protein YjgA or X96 SW:YJGA_ECOLI (P26650) (183 aa) fasta scores: E(): 0, 78.0% id in 182 aa, and to Haemophilus influenzae hypothetical protein HI1151 SW:YJGA_HAEIN (P45076) (178 aa) fasta scores: E(): 5.9e-31, 56.6% id in 175 aa; Belongs to the UPF0307 family. (182 aa) |
| | rpoC | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1406 aa) |
| | groN | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | relC | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | nusG | Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...] (181 aa) |
| | prlG | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa) |
| | tufA-2 | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | hlyT | Putative regulatory protein; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains. (162 aa) |
| | fam | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (285 aa) |
| | ftsY | Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (541 aa) |
| | nitA | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | mmrA | Putative DEAD-box helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (428 aa) |
| | glyS | Similar to Escherichia coli glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_ECOLI (P00961) (688 aa) fasta scores: E(): 0, 85.6% id in 688 aa, and to Haemophilus influenzae glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_HAEIN (P43822) (688 aa) fasta scores: E(): 0, 68.9% id in 689 aa. (689 aa) |
| | glyQ | Similar to Escherichia coli glycyl-tRNA synthetase alpha subunit GlyQ SW:SYGA_ECOLI (P00960) (303 aa) fasta scores: E(): 0, 93.7% id in 303 aa, and to Vibrio cholerae glycyl-tRNA synthetase alpha subunit GlyQ TR:Q9KVW7 (EMBL:AE004094) (330 aa) fasta scores: E(): 0, 88.8% id in 303 aa. (304 aa) |
| | rimA | Similar to Escherichia coli 50S ribosomal protein L34 RpmH SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 4.8e-19, 95.7% id in 46 aa, and to Proteus mirabilis 50S ribosomal protein L34 RpmH SW:RL34_PROMI (P22836) (47 aa) fasta scores: E(): 3.8e-18, 93.3% id in 45 aa; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | yidC | Probable membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (546 aa) |
| | atpC | ATP synthase epsilon subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | atpD | ATP synthase beta subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa) |
| | atpG | ATP synthase gamma subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | atpA | ATP synthase alpha subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpH | ATP synthase delta subunit protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa) |
| | atpF | ATP synthase subunit B protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa) |
| | atpE | ATP synthase subunit C protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa) |
| | atpB | ATP synthase subunit B protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (274 aa) |
