STRINGSTRING
rcsC rcsC aer aer YPO2515 YPO2515 barA barA arcB arcB YPO3965 YPO3965
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rcsCTwo component sensor kinase/response regulator protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (957 aa)
aerPutative methyl-accepting chemotaxis protein; Similar to Escherichia coli aerotaxis receptor Aer or Air SW:AER_ECOLI (P50466) (506 aa) fasta scores: E(): 0,47.1% id in 514 aa, and to Escherichia coli methyl-accepting chemotaxis protein II Tar or CheM SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 0, 43.3% id in 360 aa. (526 aa)
YPO2515Putative chemotactic transducer; Similar to an internal region of Pseudomonas aeruginosa chemotactic transducer PctB TR:O32443 (EMBL:D86947) (629 aa) fasta scores: E(): 3.3e-14, 27.3% id in 395 aa, and to Campylobacter jejuni putative MCP-type signal transduction protein CJ1110C TR:Q9PNI4 (EMBL:AL139077) (429 aa) fasta scores: E(): 0, 36.4% id in 407 aa. The CDS appears to be truncated at the N-terminus in comparison to the Campylobacter jejuni protein and other homologues. Insertion of an IS100 element directly upstream has probably disrupted the promoter of this CDS. Effect on the fu [...] (415 aa)
barATwo-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. (930 aa)
arcBSimilar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa. (778 aa)
YPO3965Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa. (851 aa)
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (20%) [HD]