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| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpmB | Similar to Escherichia coli 50S ribosomal protein L28 RpmB SW:RL28_ECOLI (P02428) (77 aa) fasta scores: E(): 1.1e-32, 92.2% id in 77 aa; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | rpmG | 50S ribosomal protein L33; Similar to Escherichia coli and Salmonella typhimurium 50S ribosomal protein L33 SW:RL33_ECOLI (P02436) (54 aa) fasta scores: E(): 1.7e-21, 96.3% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (71 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (346 aa) |
| | rpsl | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | far | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (702 aa) |
| | tufA | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | nusE | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | eryA | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (201 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | 50S ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | eryB | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (110 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | Similar to Escherichia coli 50S ribosomal protein L29 RpmC SW:RL29_ECOLI (P02429) (63 aa) fasta scores: E(): 1.3e-20, 93.7% id in 63 aa; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | neaA | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rplX | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa) |
| | rpmD | Similar to Escherichia coli 50S ribosomal protein L30 RpmD SW:RL30_ECOLI (P02430) (58 aa) fasta scores: E(): 1.5e-22, 86.2% id in 58 aa. (59 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (965 aa) |
| | rpsO | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | infB | Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (884 aa) |
| | rimP | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (152 aa) |
| | rpmA | Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 5e-31, 94.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L27 Vc0436 TR:Q9KUS9 (EMBL:AE004131) (86 aa) fasta scores: E(): 1.2e-29, 91.6% id in 83 aa; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (150 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (130 aa) |
| | rpsI | Similar to Escherichia coli 30S ribosomal protein S9 RpsI SW:RS9_ECOLI (P02363) (129 aa) fasta scores: E(): 0,92.2% id in 129 aa, and to Vibrio cholerae ribosomal protein S9 Vc0571 TR:Q9KUF0 (EMBL:AE004142) (130 aa) fasta scores: E(): 0, 86.9% id in 130 aa; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | relC | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | tufA-2 | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | fdhA | Selenocysteine-specific elongation factor (pseudogene); Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (462 aa) |
| | glyS | Similar to Escherichia coli glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_ECOLI (P00961) (688 aa) fasta scores: E(): 0, 85.6% id in 688 aa, and to Haemophilus influenzae glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_HAEIN (P43822) (688 aa) fasta scores: E(): 0, 68.9% id in 689 aa. (689 aa) |
| | glyQ | Similar to Escherichia coli glycyl-tRNA synthetase alpha subunit GlyQ SW:SYGA_ECOLI (P00960) (303 aa) fasta scores: E(): 0, 93.7% id in 303 aa, and to Vibrio cholerae glycyl-tRNA synthetase alpha subunit GlyQ TR:Q9KVW7 (EMBL:AE004094) (330 aa) fasta scores: E(): 0, 88.8% id in 303 aa. (304 aa) |
| | rimA | Similar to Escherichia coli 50S ribosomal protein L34 RpmH SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 4.8e-19, 95.7% id in 46 aa, and to Proteus mirabilis 50S ribosomal protein L34 RpmH SW:RL34_PROMI (P22836) (47 aa) fasta scores: E(): 3.8e-18, 93.3% id in 45 aa; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | yadB | Putative glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (321 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (875 aa) |
| | rpsP | Similar to Escherichia coli 30S ribosomal protein S16 RpsP SW:RS16_ECOLI (P02372) (82 aa) fasta scores: E(): 5.4e-26, 79.3% id in 82 aa, and to Salmonella typhimurium 30S ribosomal protein S16 RpsP SW:RS16_SALTY (P36242) (82 aa) fasta scores: E(): 8e-27, 81.7% id in 82 aa; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | rpmJ2 | Similar to Vibrio cholerae ribosomal putative protein L36 Vc0879 TR:Q9KTM3 (EMBL:AE004172) (41 aa) fasta scores: E(): 8.8e-16, 87.5% id in 40 aa, and to Neisseria meningitidis (serogroup A) putative 50S ribosomal protein L36 Rpmj2 or Nma1137 or Nmb0941 TR:Q9JQV0 (EMBL:AL162755) (41 aa) fasta scores: E(): 7.6e-14, 82.5% id in 40 aa; Belongs to the bacterial ribosomal protein bL36 family. (47 aa) |
| | ykgM | Putative ribosomal protein; Similar to Escherichia coli O157:H7 putative ribosomal protein YkgM TR:AAG54622 (EMBL:AE005206) (87 aa) fasta scores: E(): 4.1e-24, 69.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L31P family Vc0878 TR:Q9KTM4 (EMBL:AE004172) (85 aa) fasta scores: E(): 1.4e-20, 62.5% id in 80 aa; Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily. (86 aa) |
| | YPO3088 | Conserved hypothetical protein; Similar to Escherichia coli protein YbaK SW:YBAK_ECOLI (P37175) (159 aa) fasta scores: E(): 0, 77.4% id in 159 aa, and to Salmonella typhimurium protein YbaK SW:YBAK_SALTY (P37174) (159 aa) fasta scores: E(): 0, 76.1% id in 159 aa; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | cysS | Similar to Escherichia coli cysteinyl-tRNA synthetase CysS SW:SYC_ECOLI (P21888) (461 aa) fasta scores: E(): 0, 83.9% id in 461 aa, and to Vibrio cholerae cysteinyl-tRNA synthetase CysS or Vc1848 SW:SYC_VIBCH (Q9KQZ9) (459 aa) fasta scores: E(): 0, 75.5% id in 461 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa) |
| | hisS | Similar to Escherichia coli histidyl-tRNA synthetase HisS SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 0,82.0% id in 423 aa, and to Salmonella typhimurium histidyl-tRNA synthetase HisS SW:SYH_SALTY (O52765) (423 aa) fasta scores: E(): 0, 82.0% id in 423 aa. (424 aa) |
| | YPO2754 | Similar to Escherichia coli hypothetical protein YfcM SW:YFCM_ECOLI (P76938) (182 aa) fasta scores: E(): 0,70.1% id in 177 aa, and to Vibrio cholerae hypothetical protein VC2113 TR:Q9KQ88 (EMBL:AE004285) (176 aa) fasta scores: E(): 0, 60.1% id in 173 aa. (180 aa) |
| | lepA | Similar to Escherichia coli probable GTP-binding elongation factor protein LepA SW:LEPA_ECOLI (P07682) (599 aa) fasta scores: E(): 0, 92.3% id in 599 aa, and to Haemophilus influenzae GTP-binding protein LepA SW:LEPA_HAEIN (P43729) (598 aa) fasta scores: E(): 0, 87.6% id in 597 aa; YPO2716; one of 2 probable transmembrane helices predicted. (284 aa) |
| | glnS | Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS SW:SYQ_ECOLI (P00962) (553 aa) fasta scores: E(): 0, 87.2% id in 549 aa, and to Vibrio cholerae glutaminyl-tRNA synthetase GlnS TR:Q9KTA6 (EMBL:AE004181) (556 aa) fasta scores: E(): 0, 81.1% id in 551 aa. (555 aa) |
| | leuS | Similar to Escherichia coli leucyl-tRNA synthetase LeuS SW:SYL_ECOLI (P07813) (860 aa) fasta scores: E(): 0,84.8% id in 860 aa, and to Vibrio cholerae leucyl-tRNA synthetase VC0956 TR:Q9KTE6 (EMBL:AE004177) (894 aa) fasta scores: E(): 0, 74.5% id in 858 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (642 aa) |
| | fit | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (183 aa) |
| | rpmI | Similar to Escherichia coli 50S ribosomal protein L35 RpmI SW:RL35_ECOLI (P07085) (64 aa) fasta scores: E(): 1.8e-25, 89.1% id in 64 aa, and to Haemophilus influenzae 50S ribosomal protein L35 RpmI SW:RL35_HAEIN (P45519) (64 aa) fasta scores: E(): 1.2e-21, 81.3% id in 64 aa; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | pdzA | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | pheS | Similar to Escherichia coli phenylalanyl-tRNA synthetase alpha chain PheS SW:SYFA_ECOLI (P08312) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Vibrio cholerae phenylalanyl-tRNA synthetase alpha chain PheS TR:Q9KSN7 (EMBL:AE004202) (327 aa) fasta scores: E(): 0,76.1% id in 327 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | pheT | Similar to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_ECOLI (P07395) (795 aa) fasta scores: E(): 0, 83.4% id in 795 aa, and to Haemophilus influenzae phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_HAEIN (P43820) (795 aa) fasta scores: E(): 0, 64.7% id in 795 aa; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | YPO2228 | Translation initiation factor SUI1 family protein; Similar to Escherichia coli hypothetical protein YciH SW:YCIH_ECOLI (P08245) (108 aa) fasta scores: E(): 1.3e-30, 80.6% id in 108 aa, and to Salmonella typhimurium hypothetical protein YciH SW:YCIH_SALTY (P20770) (108 aa) fasta scores: E(): 1e-29, 78.7% id in 108 aa; Similar to Escherichia coli protein YciH SW:YCIH_ECOLI (P08245) (108 aa) fasta scores: E(): 1.3e-30,80.6% id in 108 aa. (108 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa) |
| | argS | Similar to Escherichia coli arginyl-tRNA synthetase ArgS SW:SYR_ECOLI (P11875) (577 aa) fasta scores: E(): 0,82.8% id in 577 aa, and to Vibrio cholerae arginyl-tRNA synthetase VC2074 TR:Q9KQC6 (EMBL:AE004281) (599 aa) fasta scores: E(): 0, 71.4% id in 577 aa. (576 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa) |
| | rpmF | 50S ribosomal protein L32; Similar to Escherichia coli, and Salmonella typhimurium 50S ribosomal protein L32 SW:RL32_ECOLI (P02435) (56 aa) fasta scores: E(): 3.4e-20, 90.7% id in 54 aa, and to Haemophilus influenzae 50S ribosomal protein L32 RpmF or Rpl32 or Hi0158 SW:RL32_HAEIN (P44368) (55 aa) fasta scores: E(): 4.3e-19, 83.0% id in 53 aa; Belongs to the bacterial ribosomal protein bL32 family. (55 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (675 aa) |
| | asnS | Similar to Escherichia coli asparaginyl-tRNA synthetase AsnS SW:SYN_ECOLI (P17242) (465 aa) fasta scores: E(): 0, 87.3% id in 465 aa, and to Haemophilus influenzae asparaginyl-tRNA synthetase AsnS SW:SYN_HAEIN (P43829) (477 aa) fasta scores: E(): 0, 79.5% id in 464 aa. (466 aa) |
| | rpsA | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | YPO1284 | Putative elongation factor P; C-terminal region is similar to similar to Synechococcus sp elongation factor P Efp SW:EFP_SYNP7 (Q54760) (185 aa) fasta scores: E(): 3.4e-17, 31.9% id in 188 aa. Similar to the C-terminal region of Escherichia coli hypothetical protein YeiP SW:YEIP_ECOLI (P33028) (275 aa) fasta scores: E(): 0, 78.0% id in 205 aa. Possible alternative translational start sites. (190 aa) |
| | YPO1265 | Putative DEAD box helicase family protein; Similar to Escherichia coli hypothetical protein YejH SW:YEJH_ECOLI (P33919) (586 aa) fasta scores: E(): 0,78.4% id in 584 aa, and to Lactobacillus casei bacteriophage A2 hypothetical protein TR:Q9T0Y3 (EMBL:AJ251789) (455 aa) fasta scores: E(): 7.7e-10, 27.9% id in 373 aa, and to Vibrio cholerae helicase-related protein VC1636 TR:Q9KRK4 (EMBL:AE004241) (657 aa) fasta scores: E(): 0, 59.8% id in 572 aa. (585 aa) |
| | rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | b2620 | SsrA-binding protein (small protein B); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...] (160 aa) |
| | drpA | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | YPO1066 | Similar to Escherichia coli hypothetical protein YaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0,65.2% id in 135 aa, and to Pseudomonas putida hypothetical protein SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 8.6e-31, 65.2% id in 135 aa, and to Streptomyces coelicolor hypothetical protein SCD95A.11 TR:Q9KXW3 (EMBL:AL357432) (145 aa) fasta scores: E(): 7.4e-13, 41.5% id in 135 aa. (138 aa) |
| | b0172 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (285 aa) |
| | rpsB | Similar to Escherichia coli 30S ribosomal protein S2 RpsB SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 0,93.8% id in 240 aa; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (366 aa) |
| | asuD | Similar to Escherichia coli lysyl-tRNA synthetase LysS SW:SYK1_ECOLI (P13030) (504 aa) fasta scores: E(): 0,85.9% id in 504 aa, and to Haemophilus influenzae lysyl-tRNA synthetase LysS SW:SYK_HAEIN (P43825) (502 aa) fasta scores: E(): 0, 68.5% id in 504 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | rpsU | 30S ribosomal protein S21; Identical to Escherichia coli and Salmonella typhimurium 30S ribosomal protein S21 RpsU SW:RS21_ECOLI (P02379) (70 aa) fasta scores: E(): 2.3e-27, 100.0% id in 70 aa, and to Buchnera aphidicola (subsp Acyrthosiphon pisum) 30S ribosomal protein S21 RpsU TR:BAB12780 (EMBL:AP001118) (71 aa) fasta scores: E(): 1e-25, 90.1% id in 71 aa; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | b0026 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa) |
| | b0023 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | b4375 | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | b4155 | Putative lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | b4147 | Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | def | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (170 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | YPO0237 | Similar to Escherichia coli hypothetical protein YhdL SW:YHDL_ECOLI (P36675) (72 aa) fasta scores: E(): 5.5e-17, 69.4% id in 62 aa. (66 aa) |
| | rplQ | Similar to Escherichia coli 50S ribosomal protein L17 RplQ SW:RL17_ECOLI (P02416) (127 aa) fasta scores: E(): 0, 94.5% id in 127 aa. (129 aa) |
| | ramA | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) |
| | rpmJ | Similar to Escherichia coli 50S ribosomal protein L36 RpmJ SW:RL36_ECOLI (P21194) (38 aa) fasta scores: E(): 2.1e-15, 94.7% id in 38 aa; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
