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creC creC cpxA cpxA envZ envZ YPO0256 YPO0256 YPO0449 YPO0449 basS basS YPO3965 YPO3965 yhjK yhjK cheM-2 cheM-2 barA barA YPO2997 YPO2997 rstB rstB YPO2000 YPO2000 narR narR cheD-2 cheD-2 aer aer cheD2 cheD2 cheD cheD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
creCSimilar to Myxococcus xanthus developmental histidine kinase sensor SasS TR:O52223 (EMBL:AF029787) (497 aa) fasta scores: E(): 1.4e-23, 28.2% id in 485 aa, and to Escherichia coli sensor protein CreC SW:CREC_ECOLI (P08401) (474 aa) fasta scores: E(): 0, 58.3% id in 470 aa. Probable sensor kinase protein of two-component regulatory system. (472 aa)
cpxASimilar to Escherichia coli two component sensor kinase, CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 0, 80.8% id in 454 aa. (458 aa)
envZSimilar to Escherichia coli osmolarity sensor protein EnvZ SW:ENVZ_ECOLI (P02933) (450 aa) fasta scores: E(): 0, 86.6% id in 440 aa, and to Yersinia enterocolitica EnvZ TR:O06468 (EMBL:Y08950) (450 aa) fasta scores: E(): 0,93.8% id in 450 aa. (450 aa)
YPO0256Two-component sensor/regulator; Similar to Salmonella typhimurium pathogenicity island regulator gene SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 46.5% id in 826 aa and to Vibrio cholerae sensory box sensor histidine kinase/response regulator VieS VC1653 TR:Q9KRI8 (EMBL:AE004243) (1146 aa) fasta scores: E(): 0, 30.4% id in 559 aa. This CDS carries both the sensor and response regulator domains. (939 aa)
YPO0449Putative exported protein; Similar to Escherichia coli hypothetical 46.0 kDa protein in aroF-rplS intergenic region YfiN SW:YFIN_ECOLI (P46139) (408 aa) fasta scores: E(): 3.1e-52, 36.524% id in 397 aa, and to Pseudomonas aeruginosa hypothetical protein Pa1120 TR:Q9I4L5 (EMBL:AE004542) (435 aa) fasta scores: E(): 2.6e-86, 55.639% id in 399 aa. (425 aa)
basSSimilar to Escherichia coli sensor protein BasS or PmrB SW:BASS_ECOLI (P30844) (363 aa) fasta scores: E(): 0,49.7% id in 354 aa, and to Salmonella typhimurium sensor protein BasS or PmrB or ParB SW:BASS_SALTY (P36557) (356 aa) fasta scores: E(): 0, 50.4% id in 349 aa. (355 aa)
YPO3965Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa. (851 aa)
yhjKPutative membrane protein; Similar to Escherichia coli protein YhjK SW:YHJK_ECOLI (P37649) (651 aa) fasta scores: E(): 0, 47.9% id in 653 aa. C-terminus is similar to the C-terminal region of Pseudomonas aeruginosa hypothetical protein PA4367 TR:AAG07755 (EMBL:AE004852) (687 aa) fasta scores: E(): 0, 29.6% id in 686 aa. (671 aa)
cheM-2Methyl-accepting chemotaxis protein II; Similar to the C-terminal regions of Escherichia coli methyl-accepting chemotaxis protein II Tar SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 0, 46.8% id in 530 aa, and Salmonella typhimurium methyl-accepting chemotaxis protein II Tar SW:MCP2_SALTY (P02941) (553 aa) fasta scores: E(): 0, 46.3% id in 525 aa. (649 aa)
barATwo-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. (930 aa)
YPO2997Putative two-component system sensor kinase; Similar to Escherichia coli sensor protein BaeS SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 6.7e-19,26.3% id in 480 aa, and to Neisseria meningitidis sensor histidine kinase NMB0594 TR:Q9K0K1 (EMBL:AE002415) (468 aa) fasta scores: E(): 2.2e-31, 30.2% id in 463 aa. Probable histidine kinase protein of a two-component system. (449 aa)
rstBTwo-component regulatory system, sensor kinase protein; Similar to Escherichia coli sensor protein RstB SW:RSTB_ECOLI (P18392) (433 aa) fasta scores: E(): 0, 69.5% id in 419 aa, and to Escherichia coli sensor protein CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 2.5e-27,28.4% id in 450 aa. (425 aa)
YPO2000Putative two-component system sensor protein; Member of a two-component regulatory system. (463 aa)
narRNitrate/nitrite sensor protein; Previously sequenced as Yersinia pestis probable nitrate/nitrite sensor protein TR:Q9ZC64 (EMBL:AL031866) (593 aa) fasta scores: E(): 0, 100.0% id in 593 aa. Similar to Escherichia coli nitrate/nitrite sensor protein NarX SW:NARX_ECOLI (P10956) (598 aa) fasta scores: E(): 0, 47.9% id in 595 aa. (593 aa)
cheD-2Similar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or CheD or B4355 SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 0, 67.3% id in 557 aa,and to Enterobacter aerogenes methyl-accepting chemotaxis serine transducer Tse SW:MCPS_ENTAE (P21822) (557 aa) fasta scores: E(): 0, 69.8% id in 559 aa. (557 aa)
aerPutative methyl-accepting chemotaxis protein; Similar to Escherichia coli aerotaxis receptor Aer or Air SW:AER_ECOLI (P50466) (506 aa) fasta scores: E(): 0,47.1% id in 514 aa, and to Escherichia coli methyl-accepting chemotaxis protein II Tar or CheM SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 0, 43.3% id in 360 aa. (526 aa)
cheD2C-terminal region similar to many eg. Escherichia coli methyl-accepting chemotaxis protein I CheD SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 0, 46.6% id in 369 aa, and to Salmonella typhimurium methyl-accepting chemotaxis citrate transducer Tcp SW:MCPC_SALTY (Q02755) (547 aa) fasta scores: E(): 0, 50.1% id in 351 aa. (595 aa)
cheDSimilar to Escherichia coli methyl-accepting chemotaxis protein I CheD SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 0, 40.2% id in 537 aa, and to Enterobacter aerogenes methyl-accepting chemotaxis serine transducer Tse SW:MCPS_ENTAE (P21822) (557 aa) fasta scores: E(): 0, 40.5% id in 523 aa. (547 aa)
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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