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YPO0833 YPO0833 YPO0245 YPO0245 YPO0369 YPO0369 YPO0853 YPO0853 YPO0869 YPO0869 xerD xerD YPO0966 YPO0966 YPO0969 YPO0969 galA galA galB galB galD galD YPO1394 YPO1394 YPO1473 YPO1473 galU galU galF galF glcA glcA ycfO ycfO nagK nagK gptB gptB manY manY gptB-2 gptB-2 YPO2036 YPO2036 YPO2174 YPO2174 manA manA mlc mlc arnD arnD arnA arnA pmrF pmrF arnB arnB manB manB YPO2576 YPO2576 nagC nagC nagA nagA glmD glmD nagE nagE pgm pgm murQ murQ glk glk crr crr nanK nanK nanE nanE nanA nanA manB-2 manB-2 manC manC prt prt ddhA ddhA ascD ascD ahpC ahpC YPO3211 YPO3211 YPO3259 YPO3259 mrsA mrsA murA murA rapZ rapZ msrQ msrQ pgi pgi murB murB YPO3817 YPO3817 b3787 b3787 nfrC nfrC glgC glgC glmS glmS glmU glmU
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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gene neighborhood
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YPO0833Putative phosphosugar isomerase; Similar to Drosophila melanogaster glucosamine--fructose-6-phosphate aminotransferase GfaT TR:Q9Y093 (EMBL:Y18628) (694 aa) fasta scores: E(): 0.00036, 22.3% id in 363 aa, and to Escherichia coli putative tagatose-6-phosphate ketose/aldose isomerase AgaS SW:AGAS_ECOLI (P42907) (384 aa) fasta scores: E(): 0, 48.0% id in 373 aa. (388 aa)
YPO0245Putative DNA-binding protein; Similar to the C-terminal DNA-binding zinc finger domains of several DNA topoisomerases e.g. Bacillus subtilis SW:TOP1_BACSU (P39814) (691 aa) fasta scores: E(): 3.3e-15, 40.7% id in 108 aa. Also similar to Escherichia coli hypothetical protein YrdD SW:YRDD_ECOLI (P45771) (169 aa) fasta scores: E(): 0, 69.0% id in 155 aa. (179 aa)
YPO0369Conserved hypothetical protein; Similar to several proteins of undefined function e.g. Escherichia coli hypothetical protein YjeE or B4168 SW:YJEE_ECOLI (P31805) (153 aa) fasta scores: E(): 3.5e-41,73.026% id in 152 aa. (156 aa)
YPO0853Putative galactosidase; Similar to Pseudomonas fluorescens arabinogalactan endo-1,4-beta-galactosidase GalA SW:GANA_PSEFL (P48841) (376 aa) fasta scores: E(): 0, 33.3% id in 387 aa, and to N-terminus of Thermotoga maritima putative arabinogalactan endo-1,4-beta-galactosidase TM1201 TR:Q9X0S8 (EMBL:AE001777) (606 aa) fasta scores: E(): 0, 50.3% id in 384 aa. (400 aa)
YPO0869Hypothetical protein; No significant database hits to the full length CDS. Weakly similar to an internal region of Burkholderia pseudomallei hypothetical protein TR:Q9ZF74 (EMBL:AF110185) (541 aa) fasta scores: E(): 0.85, 29.2% id in 185 aa. (238 aa)
xerDIntegrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the b [...] (299 aa)
YPO0966Putative kinase; No significant database matches to the full length CDS. Some similarity to internal region of Staphylococcus carnosus hydroxyethylthiazole kinase ThiM SW:THIM_STACA (Q9RGS6) (264 aa) fasta scores: E(): 8.5, 30.2% id in 106 aa. CDS is similar to YPO1473 (83.2% identity in 768 aa overlap). (765 aa)
YPO0969Hypothetical protein; No significant database hits. (740 aa)
galAAldose 1-epimerase (pseudogene); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa)
galBSimilar to Escherichia coli galactose-1-phosphate uridylyltransferase GalT or GalB SW:GAL7_ECOLI (P09148) (348 aa) fasta scores: E(): 0, 82.4% id in 347 aa. (350 aa)
galDUDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity). (338 aa)
YPO1394Putative membrane protein; Similar to Neisseria gonorrhoeae competence protein ComA SW:COMA_NEIGO (P51973) (691 aa) fasta scores: E(): 1.8e-27, 28.9% id in 714 aa, and to Escherichia coli hypothetical protein YcaI SW:YCAI_ECOLI (P37443) (780 aa) fasta scores: E(): 0, 41.9% id in 756 aa. (763 aa)
YPO1473Hypothetical protein; No significant database hits. Similar to YPO0966 (83.2% identity in 768 aa overlap) and YPO1476 (51.9% identity in 567 aa overlap). (766 aa)
galUSimilar to Escherichia coli UTP-glucose-1-phosphate uridylyltransferase SW:GALU_ECOLI (P25520) (301 aa) fasta scores: E(): 0, 73.5% id in 294 aa, and to Haemophilus influenzae UTP-glucose-1-phosphate uridylyltransferase GalU or hi0812 SW:GALU_HAEIN (P44878) (295 aa) fasta scores: E(): 0, 71.6% id in 289 aa. This CDS (GalU) is similar (64.2% in 293 aa overlap) to the adjacent CDS, YPO1540 (GalF). (296 aa)
galFSimilar to Escherichia coli UTP-glucose-1-phosphate uridylyltransferase SW:GALF_ECOLI (P78083) (297 aa) fasta scores: E(): 0, 65.3% id in 297 aa, and to Klebsiella pneumoniae UTP-glucose-1-phosphate uridylyltransferase GalF SW:GALF_KLEPN (Q48447) (298 aa) fasta scores: E(): 0, 64.3% id in 297 aa. This CDS (GalF) is similar (64.2% in 293 aa overlap) to the adjacent CDS YPO1539 (GalU). Both GalU and GalF have been designated UTP-glucose-1-phosphate uridylyltransferase. However, it has been proposed that GalF is a non-catalytic subunit of the UDP-glucose pyrophosphorylase modulating the e [...] (297 aa)
glcASimilar to Escherichia coli PTS system,glucose-specific IIBC component Ptsg or Glca or UmG SW:PTGB_ECOLI (P05053) (477 aa) fasta scores: E(): 0, 90.4% id in 477 aa, and to Salmonella typhimurium PTS system,glucose-specific IIBC component PtsG SW:PTGB_SALTY (P37439) (477 aa) fasta scores: E(): 0, 88.7% id in 477 aa. (477 aa)
ycfOBeta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (343 aa)
nagKConserved hypothetical protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. Belongs to the ROK (NagC/XylR) family. NagK subfamily. (256 aa)
gptBSimilar to Escherichia coli PTS system,mannose-specific IID component ManZ or PtsM or GptB SW:PTND_ECOLI (P08188) (286 aa) fasta scores: E(): 0, 86.6% id in 291 aa, and to Bacillus subtilis PTS system,fructose-specific IID component LevG SW:PTFD_BACSU (P26382) (275 aa) fasta scores: E(): 0, 60.4% id in 273 aa. This CDS has a small insertion at the N-terminal end relative to that of E.coli. (295 aa)
manYSimilar to Escherichia coli PTS system,mannose-specific IIC component ManY or PtsP or Pel SW:PTNC_ECOLI (P08187) (266 aa) fasta scores: E(): 0, 87.7% id in 269 aa, and to Klebsiella pneumoniae PTS system,sorbose-specific IIC component SorA SW:PTRC_KLEPN (P37082) (266 aa) fasta scores: E(): 0, 61.3% id in 266 aa. (265 aa)
gptB-2Similar to Escherichia coli PTS system,mannose-specific IIAB component ManX or PtsL or GptB SW:PTNA_ECOLI (P08186) (322 aa) fasta scores: E(): 0, 81.4% id in 323 aa, and to Streptococcus salivarius mannose-specific phosphotransferase system component iiab manL TR:Q9S4L5 (EMBL:AF130465) (330 aa) fasta scores: E(): 0, 42.5% id in 332 aa. (324 aa)
YPO2036Putative transcriptional regulatory protein; N-terminal region is similar to the N-terminus of Bacillus subtilis xylose repressor XylR SW:XYLR_BACSU (P16557) (384 aa) fasta scores: E(): 2.4e-15, 27.7% id in 256 aa. Full length CDS has weak similarity to Rhizobium sp hypothetical protein Y4FQ SW:Y4FQ_RHISN (P55455) (392 aa) fasta scores: E(): 1.4e-27, 30.1% id in 366 aa. (370 aa)
YPO2174Putative nucleotide sugar dehydrogenase; Similar to Xanthomonas campestris UDP-glucose dehydrogenase TR:Q56812 (EMBL:X79772) (445 aa) fasta scores: E(): 0, 61.3% id in 349 aa, and to Pseudomonas aeruginosa probable nucleotide sugar dehydrogenase PA3559 TR:AAG06947 (EMBL:AE004776) (464 aa) fasta scores: E(): 0,64.9% id in 447 aa. (448 aa)
manASimilar to Escherichia coli mannose-6-phosphate isomerase ManA SW:MANA_ECOLI (P00946) (391 aa) fasta scores: E(): 0, 71.0% id in 389 aa, and to Salmonella typhimurium mannose-6-phosphate isomerase ManA SW:MANA_SALTY (P25081) (391 aa) fasta scores: E(): 0, 70.2% id in 389 aa. (391 aa)
mlcLysR-family transcriptional regulatory protein (pseudogene); Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 49.10, E-value 2.4e-11. (405 aa)
arnDConserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (301 aa)
arnAProbable formyl transferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (667 aa)
pmrFProbable glycosyl transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (327 aa)
arnBConserved hypothteical protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (384 aa)
manBPhosphomannomutase; Similar to Escherichia coli phosphomannomutase ManB SW:RFK9_ECOLI (P37755) (456 aa) fasta scores: E(): 0, 61.5% id in 462 aa, to Salmonella montevideo phosphomannomutase ManB SW:MANB_SALMO (Q01411) (456 aa) fasta scores: E(): 0,61.4% id in 461 aa and to Yersinia pestis YPO3097 (457 aa) fasta scores: E(): 0, 61.4% identity in 461 aa overlap. (462 aa)
YPO2576Similar to Pseudomonas aeruginosa hypothetical protein PA5506 TR:AAG08891 (EMBL:AE004963) (285 aa) fasta scores: E(): 2.9e-10, 25.8% id in 283 aa, and to Bacillus halodurans hypothetical protein BH2940 TR:Q9K8R3 (EMBL:AP001517) (284 aa) fasta scores: E(): 7.1e-13, 24.4% id in 270 aa. (284 aa)
nagCPutative N-acetylglucosamine regulatory protein; Similar to Escherichia coli N-acetylglucosamine repressor NagC or NagR or B0676 SW:NAGC_ECOLI (P15301) (406 aa) fasta scores: E(): 0, 78.0% id in 405 aa, and to Vibrio cholerae probable N-acetylglucosamine regulatory protein VC0993 TR:Q9KTB0 (EMBL:AE004181) (404 aa) fasta scores: E(): 0, 63.3% id in 403 aa. (409 aa)
nagASimilar to Escherichia coli N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_ECOLI (P15300) (382 aa) fasta scores: E(): 0, 75.1% id in 381 aa, and to Vibrio cholerae N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_VIBCH (O32445) (378 aa) fasta scores: E(): 0, 64.1% id in 376 aa. (381 aa)
glmDPutative glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
nagESimilar to Escherichia coli PTS system,N-acetylglucosamine-specific IIABC component NagE SW:PTAA_ECOLI (P09323) (648 aa) fasta scores: E(): 0, 52.6% id in 683 aa, and to Vibrio furnissii PTS permease for N-acetylglucosamine and glucose NagE TR:P96161 (EMBL:U65014) (496 aa) fasta scores: E(): 0, 69.9% id in 495 aa. (677 aa)
pgmPhosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 0, 82.8% id in 546 aa, and to Vibrio cholerae phosphoglucomutase VC2095 TR:Q9KQA5 (EMBL:AE004283) (548 aa) fasta scores: E(): 0, 69.6% id in 546 aa. (547 aa)
murQPutative glucokinase protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (295 aa)
glkGlucokinase; Similar to Escherichia coli glucokinase Glk SW:HXKG_ECOLI (P46880) (321 aa) fasta scores: E(): 0, 79.4% id in 321 aa, and to Neisseria meningitidis (serogroup A) glucokinase Glk TR:Q9JQX3 (EMBL:AL162756) (328 aa) fasta scores: E(): 0, 46.6% id in 313 aa; Belongs to the bacterial glucokinase family. (323 aa)
crrProbable glucose-specific IIA component of a phosphoenolpyruvate-dependent phosphotransferase system (PTS). Similar to Salmonella typhimurium PTS system,glucose-specific IIA component Crr SW:PTGA_SALTY (P02908) (168 aa) fasta scores: E(): 0, 94.0% id in 168 aa, and to Escherichia coli PTS system, glucose-specific IIA component Crr SW:PTGA_ECOLI (P08837) (168 aa) fasta scores: E(): 0,92.9% id in 168 aa. (169 aa)
nanKPutative sugar kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (290 aa)
nanEPutative outer membrane protein (pseudogene); Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (233 aa)
nanASimilar to Escherichia coli N-acetylneuraminate lyase subunit NanA or Npl SW:NPL_ECOLI (P06995) (296 aa) fasta scores: E(): 1.7e-16, 29.1% id in 265 aa, and to Vibrio cholerae N-acetylneuraminate lyase, putative VC1776 TR:Q9KR67 (EMBL:AE004255) (298 aa) fasta scores: E(): 0,75.1% id in 293 aa. (297 aa)
manB-2Phosphomannomutase; Similar to Yersinia pseudotuberculosis phosphomannomutase ManB TR:Q9RCA9 (EMBL:AJ251712) (457 aa) fasta scores: E(): 0, 99.8% id in 457 aa, and to Yersinia enterocolitica phosphomannomutase RfbK or ManB TR:Q57439 (EMBL:U46859) (456 aa) fasta scores: E(): 0, 81.8% id in 456 aa. Identical to the previously sequenced Yersinia pestis phosphomannomutase ManB TR:Q9RCC3 (EMBL:AJ251713) (457 aa) fasta scores: E(): 0, 100.0% id in 457 aa. Similar to YPO2479 (61.4% identity in 461 aa overlap). (457 aa)
manCSimilar to Yersinia pseudotuberculosis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCB1 (EMBL:AJ251712) (468 aa) fasta scores: E(): 0, 99.8% id in 468 aa, and to Yersinia enterocolitica mannose-1-phosphate guanylyltransferase RfbM or ManC TR:Q56874 (EMBL:U46859) (465 aa) fasta scores: E(): 0, 80.7% id in 462 aa, and identical to the previously sequenced Yersinia pestis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCC5 (EMBL:AJ251713) (468 aa) fasta scores: E(): 0, 100.0% id in 468 aa; Belongs to the mannose-6-phosphate isomerase type 2 family. (470 aa)
prtParatose synthase; Similar to Salmonella typhi paratose synthase RfbS SW:RFBS_SALTI (P14168) (279 aa) fasta scores: E(): 0, 43.9% id in 280 aa, and to Yersinia pseudotuberculosis CDP-paratose synthetase RfbS or Prt TR:Q56946 (EMBL:U29692) (285 aa) fasta scores: E(): 0, 99.3% id in 285 aa, and identical to the previously sequenced Yersinia pestis CDP-paratose synthetase Prt TR:Q9RCC9 (EMBL:AJ251713) (285 aa) fasta scores: E(): 0, 100.0% id in 285 aa. (285 aa)
ddhASimilar to Yersinia pseudotuberculosis CDP-D-glucose-4,6-dehydratase AscB or DdhB TR:Q57329 (EMBL:L33181) (357 aa) fasta scores: E(): 0, 99.2% id in 358 aa, and to Yersinia enterocolitica CDP-glucose 4,6-dehydratase ddhb or RfbG TR:Q56861 (EMBL:U46859) (358 aa) fasta scores: E(): 0, 77.7% id in 359 aa. There is a frameshift following codon 41. The frameshift occurs within a Homopolymeric tract of 11C. The sequence has been checked and is believed to be correct. (261 aa)
ascDCdp-6-deoxy-delta-3,4-glucoseen reductase; Participates in the conversion of CDP-6-deoxy-D-glycero-L- threo-4-hexulose to 3,6-dideoxy-D-glycero-D-glycero-4-hexulose together with CDP-6-deoxy-D-glycero-L-threo-4-hexulose-3-dehydrase (E1) in two consecutive steps. The detailed mechanism of E3 is not yet resolved (By similarity). (329 aa)
ahpCSimilar to Campylobacter jejuni alkyl hydroperoxide reductase subunit C AhpC or Cj0334 TR:Q9ZI13 (EMBL:AF044271) (198 aa) fasta scores: E(): 0, 59.8% id in 199 aa, and to Vibrio cholerae antioxidant, AhpC/Tsa family Vc0731 TR:Q9KTZ9 (EMBL:AE004159) (207 aa) fasta scores: E(): 0, 71.5% id in 200 aa. (200 aa)
YPO3211Similar to Escherichia coli hypothetical protein YajF SW:YAJF_ECOLI (P23917) (302 aa) fasta scores: E(): 0,69.2% id in 299 aa, and to Vibrio cholerae ROK family protein Vc0270 TR:Q9KV86 (EMBL:AE004115) (326 aa) fasta scores: E(): 0, 46.3% id in 298 aa. (304 aa)
YPO3259Putative rpiR-family transcriptional regulatory protein; Similar to Pseudomonas aeruginosa hypothetical protein PA5506 TR:AAG08891 (EMBL:AE004963) (285 aa) fasta scores: E(): 2.8e-11, 26.0% id in 281 aa, and to Bacillus halodurans BH2940 protein TR:Q9K8R3 (EMBL:AP001517) (284 aa) fasta scores: E(): 6.7e-11, 23.1% id in 277 aa. (281 aa)
mrsAProbable phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (446 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
rapZConserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa)
msrQPutative membrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usin [...] (206 aa)
pgiSimilar to Escherichia coli glucose-6-phosphate isomerase Pgi SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 0, 87.2% id in 548 aa, and to Vibrio cholerae glucose-6-phosphate isomerase Vc0374 TR:Q9KUY4 (EMBL:AE004125) (550 aa) fasta scores: E(): 0, 76.5% id in 548 aa. (548 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
YPO3817Putative membrane protein; Similar to Escherichia coli hypothetical protein YhhM SW:YHHM_ECOLI (P37615) (119 aa) fasta scores: E(): 2.5e-08, 35.8% id in 134 aa. CDS contains and insert,residues 86 to 103, relative to the E. coli protein. (139 aa)
b3787Putative UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
nfrCUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (476 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa)
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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