STRINGSTRING
far far fmt fmt yadB yadB valS valS fdhA fdhA glyS glyS glyQ glyQ b0026 b0026 asuD asuD drpA drpA serS serS asnS asnS metG metG argS argS aspS aspS tyrS tyrS pheT pheT pheS pheS thrS thrS YPO2434 YPO2434 leuS leuS glnS glnS yegP yegP hisS hisS gltX gltX cysS cysS YPO3088 YPO3088 alaS alaS trpS trpS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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farElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (702 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa)
yadBPutative glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (321 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (965 aa)
fdhASelenocysteine-specific elongation factor (pseudogene); Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (462 aa)
glySSimilar to Escherichia coli glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_ECOLI (P00961) (688 aa) fasta scores: E(): 0, 85.6% id in 688 aa, and to Haemophilus influenzae glycyl-tRNA synthetase beta chain subunit GlyS SW:SYGB_HAEIN (P43822) (688 aa) fasta scores: E(): 0, 68.9% id in 689 aa. (689 aa)
glyQSimilar to Escherichia coli glycyl-tRNA synthetase alpha subunit GlyQ SW:SYGA_ECOLI (P00960) (303 aa) fasta scores: E(): 0, 93.7% id in 303 aa, and to Vibrio cholerae glycyl-tRNA synthetase alpha subunit GlyQ TR:Q9KVW7 (EMBL:AE004094) (330 aa) fasta scores: E(): 0, 88.8% id in 303 aa. (304 aa)
b0026isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)
asuDSimilar to Escherichia coli lysyl-tRNA synthetase LysS SW:SYK1_ECOLI (P13030) (504 aa) fasta scores: E(): 0,85.9% id in 504 aa, and to Haemophilus influenzae lysyl-tRNA synthetase LysS SW:SYK_HAEIN (P43825) (502 aa) fasta scores: E(): 0, 68.5% id in 504 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa)
drpAprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa)
asnSSimilar to Escherichia coli asparaginyl-tRNA synthetase AsnS SW:SYN_ECOLI (P17242) (465 aa) fasta scores: E(): 0, 87.3% id in 465 aa, and to Haemophilus influenzae asparaginyl-tRNA synthetase AsnS SW:SYN_HAEIN (P43829) (477 aa) fasta scores: E(): 0, 79.5% id in 464 aa. (466 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (675 aa)
argSSimilar to Escherichia coli arginyl-tRNA synthetase ArgS SW:SYR_ECOLI (P11875) (577 aa) fasta scores: E(): 0,82.8% id in 577 aa, and to Vibrio cholerae arginyl-tRNA synthetase VC2074 TR:Q9KQC6 (EMBL:AE004281) (599 aa) fasta scores: E(): 0, 71.4% id in 577 aa. (576 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa)
pheTSimilar to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_ECOLI (P07395) (795 aa) fasta scores: E(): 0, 83.4% id in 795 aa, and to Haemophilus influenzae phenylalanyl-tRNA synthetase beta chain PheT SW:SYFB_HAEIN (P43820) (795 aa) fasta scores: E(): 0, 64.7% id in 795 aa; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa)
pheSSimilar to Escherichia coli phenylalanyl-tRNA synthetase alpha chain PheS SW:SYFA_ECOLI (P08312) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Vibrio cholerae phenylalanyl-tRNA synthetase alpha chain PheS TR:Q9KSN7 (EMBL:AE004202) (327 aa) fasta scores: E(): 0,76.1% id in 327 aa; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (642 aa)
YPO2434Similar to Caulobacter crescentus hypothetical protein CC0128 TR:Q9ABU2 (EMBL:AE005687) (66 aa) fasta scores: E(): 6.5e-05, 38.983% id in 59 aa, and to the C-terminal region of Rhizobium loti hypothetical protein MLL6859 TR:BAB53070 (EMBL:AP003010) (109 aa) fasta scores: E(): 0.0025, 34.783% id in 69 aa. (70 aa)
leuSSimilar to Escherichia coli leucyl-tRNA synthetase LeuS SW:SYL_ECOLI (P07813) (860 aa) fasta scores: E(): 0,84.8% id in 860 aa, and to Vibrio cholerae leucyl-tRNA synthetase VC0956 TR:Q9KTE6 (EMBL:AE004177) (894 aa) fasta scores: E(): 0, 74.5% id in 858 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa)
glnSSimilar to Escherichia coli glutaminyl-tRNA synthetase GlnS SW:SYQ_ECOLI (P00962) (553 aa) fasta scores: E(): 0, 87.2% id in 549 aa, and to Vibrio cholerae glutaminyl-tRNA synthetase GlnS TR:Q9KTA6 (EMBL:AE004181) (556 aa) fasta scores: E(): 0, 81.1% id in 551 aa. (555 aa)
yegPSimilar to Escherichia coli hypothetical protein YegP SW:YEGP_ECOLI (P76402) (110 aa) fasta scores: E(): 3.4e-19, 53.7% id in 108 aa, and to Pseudomonas aeruginosa hypothetical protein PA0329 TR:AAG03718 (EMBL:AE004471) (110 aa) fasta scores: E(): 6.7e-15, 49.5% id in 95 aa; Belongs to the UPF0339 family. Duplicated subfamily. (112 aa)
hisSSimilar to Escherichia coli histidyl-tRNA synthetase HisS SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 0,82.0% id in 423 aa, and to Salmonella typhimurium histidyl-tRNA synthetase HisS SW:SYH_SALTY (O52765) (423 aa) fasta scores: E(): 0, 82.0% id in 423 aa. (424 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa)
cysSSimilar to Escherichia coli cysteinyl-tRNA synthetase CysS SW:SYC_ECOLI (P21888) (461 aa) fasta scores: E(): 0, 83.9% id in 461 aa, and to Vibrio cholerae cysteinyl-tRNA synthetase CysS or Vc1848 SW:SYC_VIBCH (Q9KQZ9) (459 aa) fasta scores: E(): 0, 75.5% id in 461 aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa)
YPO3088Conserved hypothetical protein; Similar to Escherichia coli protein YbaK SW:YBAK_ECOLI (P37175) (159 aa) fasta scores: E(): 0, 77.4% id in 159 aa, and to Salmonella typhimurium protein YbaK SW:YBAK_SALTY (P37174) (159 aa) fasta scores: E(): 0, 76.1% id in 159 aa; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (875 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (346 aa)
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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