STRINGSTRING
A0A0S2LHV0 A0A0S2LHV0 LYS4 LYS4 MDE1 MDE1 ARG2 ARG2 ARGJ_CRYNJ ARGJ_CRYNJ MRI1 MRI1 GLN1 GLN1 TRP1 TRP1 HIS3 HIS3 ADK1 ADK1 CBR1 CBR1 PURA_CRYNJ PURA_CRYNJ ADE2 ADE2 TMP1 TMP1 URA5 URA5 DFR1 DFR1 Q5K6V6_CRYNJ Q5K6V6_CRYNJ Q5K6Y9_CRYNJ Q5K6Y9_CRYNJ Q5K716_CRYNJ Q5K716_CRYNJ Q5K750_CRYNJ Q5K750_CRYNJ Q5K761_CRYNJ Q5K761_CRYNJ Q5K7B2_CRYNJ Q5K7B2_CRYNJ Q5K7B4_CRYNJ Q5K7B4_CRYNJ Q5K7G6_CRYNJ Q5K7G6_CRYNJ Q5K7K1_CRYNJ Q5K7K1_CRYNJ Q5K7L7_CRYNJ Q5K7L7_CRYNJ Q5K7P0_CRYNJ Q5K7P0_CRYNJ Q5K7S5_CRYNJ Q5K7S5_CRYNJ Q5K7V3_CRYNJ Q5K7V3_CRYNJ Q5K7Y8_CRYNJ Q5K7Y8_CRYNJ Q5K801_CRYNJ Q5K801_CRYNJ Q5K844_CRYNJ Q5K844_CRYNJ Q5K871_CRYNJ Q5K871_CRYNJ Q5K890_CRYNJ Q5K890_CRYNJ Q5K8C0_CRYNJ Q5K8C0_CRYNJ Q5K8G1_CRYNJ Q5K8G1_CRYNJ Q5K8Q2_CRYNJ Q5K8Q2_CRYNJ Q5K8Q9_CRYNJ Q5K8Q9_CRYNJ Q5K939_CRYNJ Q5K939_CRYNJ Q5K9A9_CRYNJ Q5K9A9_CRYNJ Q5K9D7_CRYNJ Q5K9D7_CRYNJ Q5K9E9_CRYNJ Q5K9E9_CRYNJ Q5K9G2_CRYNJ Q5K9G2_CRYNJ Q5K9L8_CRYNJ Q5K9L8_CRYNJ Q5K9M8_CRYNJ Q5K9M8_CRYNJ Q5K9W9_CRYNJ Q5K9W9_CRYNJ Q5K9Z3_CRYNJ Q5K9Z3_CRYNJ Q5KA63_CRYNJ Q5KA63_CRYNJ Q5KA93_CRYNJ Q5KA93_CRYNJ Q5KAD9_CRYNJ Q5KAD9_CRYNJ Q5KAU8_CRYNJ Q5KAU8_CRYNJ Q5KAX0_CRYNJ Q5KAX0_CRYNJ Q5KB97_CRYNJ Q5KB97_CRYNJ Q5KBD4_CRYNJ Q5KBD4_CRYNJ Q5KBM8_CRYNJ Q5KBM8_CRYNJ Q5KCC3_CRYNJ Q5KCC3_CRYNJ Q5KCD9_CRYNJ Q5KCD9_CRYNJ Q5KCG5_CRYNJ Q5KCG5_CRYNJ Q5KCJ5_CRYNJ Q5KCJ5_CRYNJ Q5KCL7_CRYNJ Q5KCL7_CRYNJ Q5KCL8_CRYNJ Q5KCL8_CRYNJ Q5KCP9_CRYNJ Q5KCP9_CRYNJ Q5KCS0_CRYNJ Q5KCS0_CRYNJ Q5KCV9_CRYNJ Q5KCV9_CRYNJ Q5KCW4_CRYNJ Q5KCW4_CRYNJ Q5KCY2_CRYNJ Q5KCY2_CRYNJ Q5KCY4_CRYNJ Q5KCY4_CRYNJ Q5KD20_CRYNJ Q5KD20_CRYNJ ADI1 ADI1 Q5KDJ8_CRYNJ Q5KDJ8_CRYNJ Q5KDJ9_CRYNJ Q5KDJ9_CRYNJ Q5KDR3_CRYNJ Q5KDR3_CRYNJ Q5KEA8_CRYNJ Q5KEA8_CRYNJ Q5KEE5_CRYNJ Q5KEE5_CRYNJ Q5KEG6_CRYNJ Q5KEG6_CRYNJ Q5KEH0_CRYNJ Q5KEH0_CRYNJ Q5KEK6_CRYNJ Q5KEK6_CRYNJ Q5KEP2_CRYNJ Q5KEP2_CRYNJ Q5KEQ7_CRYNJ Q5KEQ7_CRYNJ Q5KEZ0_CRYNJ Q5KEZ0_CRYNJ Q5KF19_CRYNJ Q5KF19_CRYNJ Q5KFA0_CRYNJ Q5KFA0_CRYNJ Q5KFC3_CRYNJ Q5KFC3_CRYNJ Q5KFL1_CRYNJ Q5KFL1_CRYNJ Q5KFS4_CRYNJ Q5KFS4_CRYNJ Q5KFV8_CRYNJ Q5KFV8_CRYNJ Q5KFX1_CRYNJ Q5KFX1_CRYNJ Q5KG49_CRYNJ Q5KG49_CRYNJ Q5KG50_CRYNJ Q5KG50_CRYNJ Q5KGH5_CRYNJ Q5KGH5_CRYNJ Q5KGK1_CRYNJ Q5KGK1_CRYNJ Q5KGR6_CRYNJ Q5KGR6_CRYNJ Q5KGT7_CRYNJ Q5KGT7_CRYNJ Q5KH06_CRYNJ Q5KH06_CRYNJ Q5KHC6_CRYNJ Q5KHC6_CRYNJ Q5KHJ2_CRYNJ Q5KHJ2_CRYNJ Q5KHK8_CRYNJ Q5KHK8_CRYNJ Q5KHM2_CRYNJ Q5KHM2_CRYNJ Q5KHX0_CRYNJ Q5KHX0_CRYNJ Q5KHZ1_CRYNJ Q5KHZ1_CRYNJ Q5KI84_CRYNJ Q5KI84_CRYNJ Q5KIC1_CRYNJ Q5KIC1_CRYNJ Q5KIG9_CRYNJ Q5KIG9_CRYNJ Q5KIH8_CRYNJ Q5KIH8_CRYNJ Q5KIP6_CRYNJ Q5KIP6_CRYNJ Q5KIW5_CRYNJ Q5KIW5_CRYNJ Q5KIZ5_CRYNJ Q5KIZ5_CRYNJ Q5KJ10_CRYNJ Q5KJ10_CRYNJ Q5KJ46_CRYNJ Q5KJ46_CRYNJ Q5KJ87_CRYNJ Q5KJ87_CRYNJ Q5KJ92_CRYNJ Q5KJ92_CRYNJ ADK2 ADK2 Q5KJB0_CRYNJ Q5KJB0_CRYNJ Q5KJH4_CRYNJ Q5KJH4_CRYNJ Q5KJY8_CRYNJ Q5KJY8_CRYNJ Q5KJZ3_CRYNJ Q5KJZ3_CRYNJ Q5KJZ9_CRYNJ Q5KJZ9_CRYNJ Q5KK07_CRYNJ Q5KK07_CRYNJ Q5KK13_CRYNJ Q5KK13_CRYNJ Q5KK33_CRYNJ Q5KK33_CRYNJ Q5KK40_CRYNJ Q5KK40_CRYNJ Q5KK45_CRYNJ Q5KK45_CRYNJ Q5KK61_CRYNJ Q5KK61_CRYNJ Q5KK62_CRYNJ Q5KK62_CRYNJ Q5KK71_CRYNJ Q5KK71_CRYNJ Q5KKB8_CRYNJ Q5KKB8_CRYNJ Q5KKU2_CRYNJ Q5KKU2_CRYNJ Q5KL19_CRYNJ Q5KL19_CRYNJ Q5KL32_CRYNJ Q5KL32_CRYNJ Q5KLA1_CRYNJ Q5KLA1_CRYNJ Q5KLW4_CRYNJ Q5KLW4_CRYNJ Q5KM31_CRYNJ Q5KM31_CRYNJ Q5KM46_CRYNJ Q5KM46_CRYNJ Q5KM49_CRYNJ Q5KM49_CRYNJ Q5KM89_CRYNJ Q5KM89_CRYNJ Q5KMB9_CRYNJ Q5KMB9_CRYNJ Q5KMJ6_CRYNJ Q5KMJ6_CRYNJ Q5KMM7_CRYNJ Q5KMM7_CRYNJ Q5KMP7_CRYNJ Q5KMP7_CRYNJ Q5KN26_CRYNJ Q5KN26_CRYNJ Q5KN32_CRYNJ Q5KN32_CRYNJ Q5KN34_CRYNJ Q5KN34_CRYNJ Q5KN70_CRYNJ Q5KN70_CRYNJ Q5KN82_CRYNJ Q5KN82_CRYNJ Q5KNA0_CRYNJ Q5KNA0_CRYNJ Q5KNA9_CRYNJ Q5KNA9_CRYNJ Q5KNB0_CRYNJ Q5KNB0_CRYNJ Q5KND5_CRYNJ Q5KND5_CRYNJ Q5KNE3_CRYNJ Q5KNE3_CRYNJ Q5KNF1_CRYNJ Q5KNF1_CRYNJ Q5KNJ3_CRYNJ Q5KNJ3_CRYNJ Q5KNK5_CRYNJ Q5KNK5_CRYNJ Q5KNM0_CRYNJ Q5KNM0_CRYNJ Q5KNM2_CRYNJ Q5KNM2_CRYNJ Q5KNQ1_CRYNJ Q5KNQ1_CRYNJ Q5KP37_CRYNJ Q5KP37_CRYNJ IMDH_CRYNJ IMDH_CRYNJ Q5KP62_CRYNJ Q5KP62_CRYNJ ITPA_CRYNJ ITPA_CRYNJ ILV2 ILV2 Q5KPK7_CRYNJ Q5KPK7_CRYNJ Q5KPL5_CRYNJ Q5KPL5_CRYNJ Q5KPM3_CRYNJ Q5KPM3_CRYNJ Q5KPM5_CRYNJ Q5KPM5_CRYNJ Q5KPQ0_CRYNJ Q5KPQ0_CRYNJ MTAP_CRYNJ MTAP_CRYNJ Q5KQ73_CRYNJ Q5KQ73_CRYNJ Q5KQ87_CRYNJ Q5KQ87_CRYNJ
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A0S2LHV0Uncharacterized protein. (278 aa)
LYS4Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (728 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (244 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (565 aa)
ARGJ_CRYNJArginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (476 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (393 aa)
GLN1Glutamine synthetase. (358 aa)
TRP1Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (752 aa)
HIS3Imidazoleglycerol-phosphate dehydratase; Imidazole glycerol-phosphate dehydratase required for histidine biosynthesis; Belongs to the imidazoleglycerol-phosphate dehydratase family. (202 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (269 aa)
CBR1NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity). (294 aa)
PURA_CRYNJAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (430 aa)
ADE2Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (582 aa)
TMP1Thymidylate synthase. (317 aa)
URA5Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. (225 aa)
DFR1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. (229 aa)
Q5K6V6_CRYNJAdenosine kinase, putative. (357 aa)
Q5K6Y9_CRYNJCystathionine gamma-lyase, putative. (466 aa)
Q5K716_CRYNJAcetolactate synthase, putative. (357 aa)
Q5K750_CRYNJCytoplasm protein, putative; Belongs to the cytochrome b5 family. (260 aa)
Q5K761_CRYNJBranched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
Q5K7B2_CRYNJGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (160 aa)
Q5K7B4_CRYNJPurine nucleotide biosynthesis-related protein, putative. (802 aa)
Q5K7G6_CRYNJDAO domain-containing protein. (480 aa)
Q5K7K1_CRYNJUncharacterized protein. (415 aa)
Q5K7L7_CRYNJExpressed protein. (381 aa)
Q5K7P0_CRYNJAconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (787 aa)
Q5K7S5_CRYNJdUTP diphosphatase, putative. (176 aa)
Q5K7V3_CRYNJUncharacterized protein. (1155 aa)
Q5K7Y8_CRYNJChorismate mutase. (296 aa)
Q5K801_CRYNJCytoplasm protein, putative. (290 aa)
Q5K844_CRYNJAsparaginase, putative. (394 aa)
Q5K871_CRYNJCNNM transmembrane domain-containing protein. (967 aa)
Q5K890_CRYNJOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (269 aa)
Q5K8C0_CRYNJGlutamate-5-semialdehyde dehydrogenase, putative. (460 aa)
Q5K8G1_CRYNJNADPH:adrenodoxin oxidoreductase, mitochondrial. (539 aa)
Q5K8Q2_CRYNJOrnithine aminotransferase. (452 aa)
Q5K8Q9_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (617 aa)
Q5K939_CRYNJPrephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (446 aa)
Q5K9A9_CRYNJRibonucleoside-diphosphate reductase, putative. (401 aa)
Q5K9D7_CRYNJ5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase, putative. (763 aa)
Q5K9E9_CRYNJGMP synthase (Glutamine-hydrolyzing), putative. (544 aa)
Q5K9G2_CRYNJAminotran_1_2 domain-containing protein. (529 aa)
Q5K9L8_CRYNJRibonucleotide reductase small subunit, putative. (430 aa)
Q5K9M8_CRYNJThreonine dehydratase. (590 aa)
Q5K9W9_CRYNJCytoplasm protein, putative. (572 aa)
Q5K9Z3_CRYNJL-serine ammonia-lyase, putative. (398 aa)
Q5KA63_CRYNJGlutamate synthase (NADH), putative. (2135 aa)
Q5KA93_CRYNJHomocysteine S-methyltransferase, putative. (381 aa)
Q5KAD9_CRYNJHomoserine dehydrogenase. (375 aa)
Q5KAU8_CRYNJSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (499 aa)
Q5KAX0_CRYNJNucleoside-diphosphate kinase, putative; Belongs to the NDK family. (223 aa)
Q5KB97_CRYNJPhosphoribosylformylglycinamidine synthase, putative. (1355 aa)
Q5KBD4_CRYNJHomoserine kinase, putative. (357 aa)
Q5KBM8_CRYNJAspartate kinase, putative. (615 aa)
Q5KCC3_CRYNJGlutamate 5-kinase, putative. (511 aa)
Q5KCD9_CRYNJPhosphoserine transaminase, putative. (411 aa)
Q5KCG5_CRYNJAsparagine synthase (Glutamine-hydrolyzing), putative. (592 aa)
Q5KCJ5_CRYNJCytochrome-b5 reductase, putative. (352 aa)
Q5KCL7_CRYNJ2-isopropylmalate synthase, putative. (639 aa)
Q5KCL8_CRYNJDihydroxy-acid dehydratase, putative. (596 aa)
Q5KCP9_CRYNJArylformamidase, putative. (451 aa)
Q5KCS0_CRYNJCytochrome b5, putative; Belongs to the cytochrome b5 family. (158 aa)
Q5KCV9_CRYNJAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (196 aa)
Q5KCW4_CRYNJDelta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (546 aa)
Q5KCY2_CRYNJDihydrofolate synthase, putative. (536 aa)
Q5KCY4_CRYNJChorismate synthase. (421 aa)
Q5KD20_CRYNJBranched-chain-amino-acid transaminase, putative. (384 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (187 aa)
Q5KDJ8_CRYNJDAO domain-containing protein. (494 aa)
Q5KDJ9_CRYNJExpressed protein. (94 aa)
Q5KDR3_CRYNJAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
Q5KEA8_CRYNJSpermidine synthase, putative; Belongs to the spermidine/spermine synthase family. (748 aa)
Q5KEE5_CRYNJUncharacterized protein. (263 aa)
Q5KEG6_CRYNJFolic acid and derivative metabolism-related protein, putative. (1021 aa)
Q5KEH0_CRYNJArginase; Belongs to the arginase family. (398 aa)
Q5KEK6_CRYNJAminoadipate-semialdehyde dehydrogenase, putative. (1409 aa)
Q5KEP2_CRYNJDihydroxy-acid dehydratase, putative. (636 aa)
Q5KEQ7_CRYNJAminotran_1_2 domain-containing protein. (480 aa)
Q5KEZ0_CRYNJMethylenetetrahydrofolate dehydrogenase (NAD+), putative. (367 aa)
Q5KF19_CRYNJAnthranilate synthase, putative. (534 aa)
Q5KFA0_CRYNJKetol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (401 aa)
Q5KFC3_CRYNJArg-6 protein, mitochondrial, putative; In the N-terminal section; belongs to the acetylglutamate kinase family. (924 aa)
Q5KFL1_CRYNJDihydropyrimidinase, putative. (370 aa)
Q5KFS4_CRYNJPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (313 aa)
Q5KFV8_CRYNJUridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (275 aa)
Q5KFX1_CRYNJNucleoside-diphosphatase, putative; Belongs to the GDA1/CD39 NTPase family. (977 aa)
Q5KG49_CRYNJProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (603 aa)
Q5KG50_CRYNJProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (443 aa)
Q5KGH5_CRYNJHemolysin, putative. (782 aa)
Q5KGK1_CRYNJRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (863 aa)
Q5KGR6_CRYNJNucleoside diphosphate kinase. (152 aa)
Q5KGT7_CRYNJPALP domain-containing protein. (331 aa)
Q5KH06_CRYNJExpressed protein. (873 aa)
Q5KHC6_CRYNJDNA repair protein rad16, putative. (1045 aa)
Q5KHJ2_CRYNJSaccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (395 aa)
Q5KHK8_CRYNJHistidine biosynthesis trifunctional protein. (852 aa)
Q5KHM2_CRYNJNucleoside transporter. (618 aa)
Q5KHX0_CRYNJAdenine phosphoribosyltransferase, putative. (178 aa)
Q5KHZ1_CRYNJGuanylate kinase, putative. (217 aa)
Q5KI84_CRYNJIsocitrate dehydrogenase, putative. (370 aa)
Q5KIC1_CRYNJArginase, putative; Belongs to the arginase family. (398 aa)
Q5KIG9_CRYNJUncharacterized protein. (138 aa)
Q5KIH8_CRYNJUncharacterized protein. (323 aa)
Q5KIP6_CRYNJUncharacterized protein. (274 aa)
Q5KIW5_CRYNJATP phosphoribosyltransferase, putative. (357 aa)
Q5KIZ5_CRYNJHomocitrate synthase, putative; Belongs to the alpha-IPM synthase/homocitrate synthase family. (491 aa)
Q5KJ10_CRYNJCarbamoyl-phosphate synthase (Glutamine-hydrolyzing), putative. (446 aa)
Q5KJ46_CRYNJArgininosuccinate synthase, putative. (429 aa)
Q5KJ87_CRYNJAdenosylhomocysteinase. (431 aa)
Q5KJ92_CRYNJNAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1056 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (334 aa)
Q5KJB0_CRYNJResponse to stress-related protein, putative; Belongs to the globin family. (504 aa)
Q5KJH4_CRYNJFSH1 domain-containing protein. (301 aa)
Q5KJY8_CRYNJOrnithine decarboxylase, putative; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (527 aa)
Q5KJZ3_CRYNJFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)
Q5KJZ9_CRYNJHistidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (349 aa)
Q5KK07_CRYNJAmidophosphoribosyltransferase. (554 aa)
Q5KK13_CRYNJThymidylate kinase, putative. (217 aa)
Q5KK33_CRYNJArgininosuccinate lyase, putative. (466 aa)
Q5KK40_CRYNJAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (409 aa)
Q5KK45_CRYNJOrnithine carbamoyltransferase, putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (373 aa)
Q5KK61_CRYNJPhosphoribosylglycinamide formyltransferase, putative. (265 aa)
Q5KK62_CRYNJDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (526 aa)
Q5KK71_CRYNJFolic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. (735 aa)
Q5KKB8_CRYNJAMP deaminase, putative. (997 aa)
Q5KKU2_CRYNJExpressed protein. (845 aa)
Q5KL19_CRYNJGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1047 aa)
Q5KL32_CRYNJGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
Q5KLA1_CRYNJCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (625 aa)
Q5KLW4_CRYNJExpressed protein. (744 aa)
Q5KM31_CRYNJAminotran_1_2 domain-containing protein. (491 aa)
Q5KM46_CRYNJHistidinol-phosphate transaminase, putative. (410 aa)
Q5KM49_CRYNJAminotran_1_2 domain-containing protein. (571 aa)
Q5KM89_CRYNJNADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
Q5KMB9_CRYNJRmlD_sub_bind domain-containing protein. (303 aa)
Q5KMJ6_CRYNJ1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (276 aa)
Q5KMM7_CRYNJThreonine synthase, putative. (547 aa)
Q5KMP7_CRYNJdCMP deaminase, putative. (349 aa)
Q5KN26_CRYNJPrephenate dehydratase domain-containing protein. (314 aa)
Q5KN32_CRYNJIMP cyclohydrolase, putative. (120 aa)
Q5KN34_CRYNJAnthranilate phosphoribosyltransferase, putative. (434 aa)
Q5KN70_CRYNJD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (508 aa)
Q5KN82_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (633 aa)
Q5KNA0_CRYNJImidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (619 aa)
Q5KNA9_CRYNJSuccinate-semialdehyde dehydrogenase [NAD(P)+], putative; Belongs to the aldehyde dehydrogenase family. (580 aa)
Q5KNB0_CRYNJDihydroorotase, putative. (353 aa)
Q5KND5_CRYNJGlutamine synthetase, putative; Belongs to the glutamine synthetase family. (482 aa)
Q5KNE3_CRYNJPurine nucleotide biosynthesis-related protein, putative. (605 aa)
Q5KNF1_CRYNJDAO domain-containing protein. (447 aa)
Q5KNJ3_CRYNJTryptophan synthase. (715 aa)
Q5KNK5_CRYNJCystathionine beta-synthase, putative. (398 aa)
Q5KNM0_CRYNJAcetylornithine transaminase, putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
Q5KNM2_CRYNJAspartate carbamoyltransferase, putative. (2333 aa)
Q5KNQ1_CRYNJ4-amino-4-deoxychorismate synthase, putative. (809 aa)
Q5KP37_CRYNJ3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (373 aa)
IMDH_CRYNJInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (544 aa)
Q5KP62_CRYNJS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (397 aa)
ITPA_CRYNJInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (189 aa)
ILV2Acetolactate synthase, mitochondrial; Belongs to the TPP enzyme family. (718 aa)
Q5KPK7_CRYNJAspartate-semialdehyde dehydrogenase, putative. (365 aa)
Q5KPL5_CRYNJSaccharopine dehydrogenase (NADP+, L-glutamate-forming), putative. (934 aa)
Q5KPM3_CRYNJ3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (762 aa)
Q5KPM5_CRYNJAmmonium transporter. (575 aa)
Q5KPQ0_CRYNJExpressed protein. (342 aa)
MTAP_CRYNJS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (303 aa)
Q5KQ73_CRYNJD-3-phosphoglycerate dehydrogenase, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (357 aa)
Q5KQ87_CRYNJAdenosylmethionine decarboxylase, putative. (460 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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