node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DFR1 | Q5KCY2_CRYNJ | Q07801 | Q5KCY2 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Dihydrofolate synthase, putative. | 0.988 |
DFR1 | Q5KJH4_CRYNJ | Q07801 | Q5KJH4 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | FSH1 domain-containing protein. | 0.958 |
DFR1 | Q5KJZ3_CRYNJ | Q07801 | Q5KJZ3 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.988 |
DFR1 | Q5KK71_CRYNJ | Q07801 | Q5KK71 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.650 |
DFR1 | TMP1 | Q07801 | P0CS12 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Thymidylate synthase. | 0.999 |
Q5KCY2_CRYNJ | DFR1 | Q5KCY2 | Q07801 | Dihydrofolate synthase, putative. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.988 |
Q5KCY2_CRYNJ | Q5KJH4_CRYNJ | Q5KCY2 | Q5KJH4 | Dihydrofolate synthase, putative. | FSH1 domain-containing protein. | 0.743 |
Q5KCY2_CRYNJ | Q5KJZ3_CRYNJ | Q5KCY2 | Q5KJZ3 | Dihydrofolate synthase, putative. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.917 |
Q5KCY2_CRYNJ | Q5KK71_CRYNJ | Q5KCY2 | Q5KK71 | Dihydrofolate synthase, putative. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.989 |
Q5KCY2_CRYNJ | TMP1 | Q5KCY2 | P0CS12 | Dihydrofolate synthase, putative. | Thymidylate synthase. | 0.946 |
Q5KJH4_CRYNJ | DFR1 | Q5KJH4 | Q07801 | FSH1 domain-containing protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.958 |
Q5KJH4_CRYNJ | Q5KCY2_CRYNJ | Q5KJH4 | Q5KCY2 | FSH1 domain-containing protein. | Dihydrofolate synthase, putative. | 0.743 |
Q5KJH4_CRYNJ | Q5KJZ3_CRYNJ | Q5KJH4 | Q5KJZ3 | FSH1 domain-containing protein. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.742 |
Q5KJH4_CRYNJ | Q5KK71_CRYNJ | Q5KJH4 | Q5KK71 | FSH1 domain-containing protein. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.608 |
Q5KJH4_CRYNJ | TMP1 | Q5KJH4 | P0CS12 | FSH1 domain-containing protein. | Thymidylate synthase. | 0.949 |
Q5KJZ3_CRYNJ | DFR1 | Q5KJZ3 | Q07801 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.988 |
Q5KJZ3_CRYNJ | Q5KCY2_CRYNJ | Q5KJZ3 | Q5KCY2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate synthase, putative. | 0.917 |
Q5KJZ3_CRYNJ | Q5KJH4_CRYNJ | Q5KJZ3 | Q5KJH4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | FSH1 domain-containing protein. | 0.742 |
Q5KJZ3_CRYNJ | Q5KK71_CRYNJ | Q5KJZ3 | Q5KK71 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.998 |
Q5KJZ3_CRYNJ | TMP1 | Q5KJZ3 | P0CS12 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase. | 0.946 |