STRINGSTRING
A0A0S2LIU2 A0A0S2LIU2 A0A0S2M600 A0A0S2M600 PSF2 PSF2 PSF3 PSF3 TOF1 TOF1 Q5K7N5_CRYNJ Q5K7N5_CRYNJ Q5KAP5_CRYNJ Q5KAP5_CRYNJ Q5KDY4_CRYNJ Q5KDY4_CRYNJ MCM7 MCM7 Q5KH26_CRYNJ Q5KH26_CRYNJ Q5KLG5_CRYNJ Q5KLG5_CRYNJ Q5KLP9_CRYNJ Q5KLP9_CRYNJ Q5KQ07_CRYNJ Q5KQ07_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0S2LIU2Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (386 aa)
A0A0S2M600Sld5 domain-containing protein. (350 aa)
PSF2DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (185 aa)
PSF3DNA replication complex GINS protein PSF3; The GINS complex plays an essential role in the initiation of DNA replication. (189 aa)
TOF1Topoisomerase 1-associated factor 1; Involved in chromosome segregation during meiosis and DNA damage repair; Belongs to the timeless family. (1074 aa)
Q5K7N5_CRYNJDNA helicase; Belongs to the MCM family. (989 aa)
Q5KAP5_CRYNJWD_REPEATS_REGION domain-containing protein. (1055 aa)
Q5KDY4_CRYNJDNA helicase; Belongs to the MCM family. (932 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (788 aa)
Q5KH26_CRYNJCell division control protein 45, putative. (701 aa)
Q5KLG5_CRYNJDNA helicase; Belongs to the MCM family. (739 aa)
Q5KLP9_CRYNJDNA helicase; Belongs to the MCM family. (963 aa)
Q5KQ07_CRYNJDNA helicase; Belongs to the MCM family. (856 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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