node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0S2LHZ7 | DFR1 | A0A0S2LHZ7 | Q07801 | Uncharacterized protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.620 |
A0A0S2LHZ7 | Q5KEZ0_CRYNJ | A0A0S2LHZ7 | Q5KEZ0 | Uncharacterized protein. | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | 0.985 |
A0A0S2LHZ7 | Q5KK71_CRYNJ | A0A0S2LHZ7 | Q5KK71 | Uncharacterized protein. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.606 |
A0A0S2LHZ7 | Q5KLK7_CRYNJ | A0A0S2LHZ7 | Q5KLK7 | Uncharacterized protein. | GTP cyclohydrolase I, putative. | 0.597 |
DFR1 | A0A0S2LHZ7 | Q07801 | A0A0S2LHZ7 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Uncharacterized protein. | 0.620 |
DFR1 | Q5KCY2_CRYNJ | Q07801 | Q5KCY2 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Dihydrofolate synthase, putative. | 0.988 |
DFR1 | Q5KEZ0_CRYNJ | Q07801 | Q5KEZ0 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | 0.901 |
DFR1 | Q5KJZ3_CRYNJ | Q07801 | Q5KJZ3 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.988 |
DFR1 | Q5KK71_CRYNJ | Q07801 | Q5KK71 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.650 |
DFR1 | Q5KLK7_CRYNJ | Q07801 | Q5KLK7 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | GTP cyclohydrolase I, putative. | 0.627 |
DFR1 | Q5KNQ1_CRYNJ | Q07801 | Q5KNQ1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 4-amino-4-deoxychorismate synthase, putative. | 0.649 |
Q5KCY2_CRYNJ | DFR1 | Q5KCY2 | Q07801 | Dihydrofolate synthase, putative. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.988 |
Q5KCY2_CRYNJ | Q5KEZ0_CRYNJ | Q5KCY2 | Q5KEZ0 | Dihydrofolate synthase, putative. | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | 0.761 |
Q5KCY2_CRYNJ | Q5KJZ3_CRYNJ | Q5KCY2 | Q5KJZ3 | Dihydrofolate synthase, putative. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.917 |
Q5KCY2_CRYNJ | Q5KK71_CRYNJ | Q5KCY2 | Q5KK71 | Dihydrofolate synthase, putative. | Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. | 0.989 |
Q5KCY2_CRYNJ | Q5KLK7_CRYNJ | Q5KCY2 | Q5KLK7 | Dihydrofolate synthase, putative. | GTP cyclohydrolase I, putative. | 0.676 |
Q5KCY2_CRYNJ | Q5KNQ1_CRYNJ | Q5KCY2 | Q5KNQ1 | Dihydrofolate synthase, putative. | 4-amino-4-deoxychorismate synthase, putative. | 0.695 |
Q5KEZ0_CRYNJ | A0A0S2LHZ7 | Q5KEZ0 | A0A0S2LHZ7 | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | Uncharacterized protein. | 0.985 |
Q5KEZ0_CRYNJ | DFR1 | Q5KEZ0 | Q07801 | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. | 0.901 |
Q5KEZ0_CRYNJ | Q5KCY2_CRYNJ | Q5KEZ0 | Q5KCY2 | Methylenetetrahydrofolate dehydrogenase (NAD+), putative. | Dihydrofolate synthase, putative. | 0.761 |