STRINGSTRING
DFR1 DFR1 Q5K8Q9_CRYNJ Q5K8Q9_CRYNJ Q5KDI7_CRYNJ Q5KDI7_CRYNJ Q5KEA8_CRYNJ Q5KEA8_CRYNJ Q5KEG6_CRYNJ Q5KEG6_CRYNJ Q5KEZ0_CRYNJ Q5KEZ0_CRYNJ Q5KFS4_CRYNJ Q5KFS4_CRYNJ Q5KHJ2_CRYNJ Q5KHJ2_CRYNJ Q5KN82_CRYNJ Q5KN82_CRYNJ Q5KPL5_CRYNJ Q5KPL5_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DFR1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. (229 aa)
Q5K8Q9_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (617 aa)
Q5KDI7_CRYNJFMN_red domain-containing protein. (213 aa)
Q5KEA8_CRYNJSpermidine synthase, putative; Belongs to the spermidine/spermine synthase family. (748 aa)
Q5KEG6_CRYNJFolic acid and derivative metabolism-related protein, putative. (1021 aa)
Q5KEZ0_CRYNJMethylenetetrahydrofolate dehydrogenase (NAD+), putative. (367 aa)
Q5KFS4_CRYNJPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (313 aa)
Q5KHJ2_CRYNJSaccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (395 aa)
Q5KN82_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (633 aa)
Q5KPL5_CRYNJSaccharopine dehydrogenase (NADP+, L-glutamate-forming), putative. (934 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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