STRINGSTRING
Q5KLA3_CRYNJ Q5KLA3_CRYNJ Q5KL82_CRYNJ Q5KL82_CRYNJ Q5KL73_CRYNJ Q5KL73_CRYNJ Q5KL21_CRYNJ Q5KL21_CRYNJ Q5KKY9_CRYNJ Q5KKY9_CRYNJ Q5KKF8_CRYNJ Q5KKF8_CRYNJ Q5KKA4_CRYNJ Q5KKA4_CRYNJ Q5KK75_CRYNJ Q5KK75_CRYNJ Q5KK73_CRYNJ Q5KK73_CRYNJ Q5KK61_CRYNJ Q5KK61_CRYNJ Q5KK45_CRYNJ Q5KK45_CRYNJ Q5KK40_CRYNJ Q5KK40_CRYNJ Q5KK34_CRYNJ Q5KK34_CRYNJ Q5KK29_CRYNJ Q5KK29_CRYNJ Q5KJP7_CRYNJ Q5KJP7_CRYNJ Q5KJJ0_CRYNJ Q5KJJ0_CRYNJ Q5KJG5_CRYNJ Q5KJG5_CRYNJ Q5KJC4_CRYNJ Q5KJC4_CRYNJ Q5KJ97_CRYNJ Q5KJ97_CRYNJ Q5KJ72_CRYNJ Q5KJ72_CRYNJ Q5KIN8_CRYNJ Q5KIN8_CRYNJ Q5KHU5_CRYNJ Q5KHU5_CRYNJ Q5KHK0_CRYNJ Q5KHK0_CRYNJ Q5KHB1_CRYNJ Q5KHB1_CRYNJ Q5KH09_CRYNJ Q5KH09_CRYNJ Q5KGZ1_CRYNJ Q5KGZ1_CRYNJ Q5KGU7_CRYNJ Q5KGU7_CRYNJ Q5KGI1_CRYNJ Q5KGI1_CRYNJ Q5KGE9_CRYNJ Q5KGE9_CRYNJ Q5KGC2_CRYNJ Q5KGC2_CRYNJ Q5KF94_CRYNJ Q5KF94_CRYNJ Q5KEZ6_CRYNJ Q5KEZ6_CRYNJ Q5KES2_CRYNJ Q5KES2_CRYNJ Q5KEJ8_CRYNJ Q5KEJ8_CRYNJ Q5KE46_CRYNJ Q5KE46_CRYNJ Q5KDK9_CRYNJ Q5KDK9_CRYNJ Q5KDE7_CRYNJ Q5KDE7_CRYNJ Q5KDC4_CRYNJ Q5KDC4_CRYNJ Q5KCT3_CRYNJ Q5KCT3_CRYNJ Q5KCG2_CRYNJ Q5KCG2_CRYNJ Q5KBW8_CRYNJ Q5KBW8_CRYNJ Q5KBP9_CRYNJ Q5KBP9_CRYNJ TRM5 TRM5 Q5KBH2_CRYNJ Q5KBH2_CRYNJ Q5KB94_CRYNJ Q5KB94_CRYNJ Q5KAX6_CRYNJ Q5KAX6_CRYNJ Q5KAV0_CRYNJ Q5KAV0_CRYNJ Q5KAU8_CRYNJ Q5KAU8_CRYNJ Q5KAS2_CRYNJ Q5KAS2_CRYNJ Q5KAH5_CRYNJ Q5KAH5_CRYNJ Q5KAE4_CRYNJ Q5KAE4_CRYNJ Q5KAD8_CRYNJ Q5KAD8_CRYNJ Q5KA93_CRYNJ Q5KA93_CRYNJ Q5KA28_CRYNJ Q5KA28_CRYNJ Q5KA00_CRYNJ Q5KA00_CRYNJ EFM4 EFM4 Q5K9X0_CRYNJ Q5K9X0_CRYNJ Q5K9U5_CRYNJ Q5K9U5_CRYNJ COQ3 COQ3 Q5K9Q4_CRYNJ Q5K9Q4_CRYNJ Q5K9Q0_CRYNJ Q5K9Q0_CRYNJ Q5K9D7_CRYNJ Q5K9D7_CRYNJ Q5K948_CRYNJ Q5K948_CRYNJ Q5K945_CRYNJ Q5K945_CRYNJ Q5K943_CRYNJ Q5K943_CRYNJ Q5K933_CRYNJ Q5K933_CRYNJ Q5K8X7_CRYNJ Q5K8X7_CRYNJ Q5K8W8_CRYNJ Q5K8W8_CRYNJ Q5K8J4_CRYNJ Q5K8J4_CRYNJ Q5K8K7_CRYNJ Q5K8K7_CRYNJ Q5K8A7_CRYNJ Q5K8A7_CRYNJ Q5K870_CRYNJ Q5K870_CRYNJ Q5K829_CRYNJ Q5K829_CRYNJ Q5K7V3_CRYNJ Q5K7V3_CRYNJ Q5K7I2_CRYNJ Q5K7I2_CRYNJ Q5K780_CRYNJ Q5K780_CRYNJ Q5K775_CRYNJ Q5K775_CRYNJ TRM8 TRM8 SPB1 SPB1 TRM82 TRM82 TMP1 TMP1 TRM10 TRM10 TRM61 TRM61 SET5 SET5 RMT2 RMT2 EFM7 EFM7 ABD1 ABD1 PPM1 PPM1 SET2 SET2 SET1 SET1 DOT1 DOT1 A0A0S2M6K2 A0A0S2M6K2 A0A0S2M697 A0A0S2M697 A0A0S2M5Y1 A0A0S2M5Y1 A0A0S2LJ70 A0A0S2LJ70 A0A0S2LI77 A0A0S2LI77 A0A0S2LI74 A0A0S2LI74 Q5KP70_CRYNJ Q5KP70_CRYNJ Q5KPG9_CRYNJ Q5KPG9_CRYNJ Q5KPK4_CRYNJ Q5KPK4_CRYNJ Q5KPM9_CRYNJ Q5KPM9_CRYNJ COQ5 COQ5 Q5KQ20_CRYNJ Q5KQ20_CRYNJ Q5KN32_CRYNJ Q5KN32_CRYNJ EFM6 EFM6 Q5KNA5_CRYNJ Q5KNA5_CRYNJ Q5KMC0_CRYNJ Q5KMC0_CRYNJ Q5KNE3_CRYNJ Q5KNE3_CRYNJ Q5KNF3_CRYNJ Q5KNF3_CRYNJ Q5KNM2_CRYNJ Q5KNM2_CRYNJ Q5KNX3_CRYNJ Q5KNX3_CRYNJ Q5KM72_CRYNJ Q5KM72_CRYNJ Q5KM39_CRYNJ Q5KM39_CRYNJ Q5KM24_CRYNJ Q5KM24_CRYNJ Q5KLI5_CRYNJ Q5KLI5_CRYNJ Q5KLI2_CRYNJ Q5KLI2_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q5KLA3_CRYNJMethyltransf_25 domain-containing protein. (275 aa)
Q5KL82_CRYNJUncharacterized protein. (477 aa)
Q5KL73_CRYNJProtein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (449 aa)
Q5KL21_CRYNJProtein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (257 aa)
Q5KKY9_CRYNJExpressed protein. (443 aa)
Q5KKF8_CRYNJTranscriptional activator, putative. (499 aa)
Q5KKA4_CRYNJSET domain-containing protein. (1119 aa)
Q5KK75_CRYNJCytoplasm protein, putative. (455 aa)
Q5KK73_CRYNJUncharacterized protein; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (482 aa)
Q5KK61_CRYNJPhosphoribosylglycinamide formyltransferase, putative. (265 aa)
Q5KK45_CRYNJOrnithine carbamoyltransferase, putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (373 aa)
Q5KK40_CRYNJAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (409 aa)
Q5KK34_CRYNJProtein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (545 aa)
Q5KK29_CRYNJProtein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (856 aa)
Q5KJP7_CRYNJExpressed protein. (430 aa)
Q5KJJ0_CRYNJS-adenosylmethionine-dependent methyltransferase, putative. (347 aa)
Q5KJG5_CRYNJProtein-arginine N-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (450 aa)
Q5KJC4_CRYNJUncharacterized protein. (489 aa)
Q5KJ97_CRYNJtRNA (Cytosine-5-)-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (763 aa)
Q5KJ72_CRYNJUncharacterized protein. (265 aa)
Q5KIN8_CRYNJRibosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (460 aa)
Q5KHU5_CRYNJUncharacterized protein. (218 aa)
Q5KHK0_CRYNJPhosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (315 aa)
Q5KHB1_CRYNJCytoplasm protein, putative. (422 aa)
Q5KH09_CRYNJUncharacterized protein. (427 aa)
Q5KGZ1_CRYNJZn(2)-C6 fungal-type domain-containing protein. (427 aa)
Q5KGU7_CRYNJArginine N-methyltransferase 3, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (575 aa)
Q5KGI1_CRYNJNucleus protein, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (543 aa)
Q5KGE9_CRYNJmRNA methyltransferase, putative; Belongs to the MT-A70-like family. (406 aa)
Q5KGC2_CRYNJMethionyl-tRNA formyltransferase, putative. (382 aa)
Q5KF94_CRYNJExpressed protein. (556 aa)
Q5KEZ6_CRYNJDiphthine synthase, putative. (337 aa)
Q5KES2_CRYNJUncharacterized protein. (354 aa)
Q5KEJ8_CRYNJMethyltransf_11 domain-containing protein. (418 aa)
Q5KE46_CRYNJTranscriptional activator, putative. (572 aa)
Q5KDK9_CRYNJCytoplasm protein, putative. (640 aa)
Q5KDE7_CRYNJPhosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (1161 aa)
Q5KDC4_CRYNJUncharacterized protein. (671 aa)
Q5KCT3_CRYNJExpressed protein. (247 aa)
Q5KCG2_CRYNJUncharacterized protein. (340 aa)
Q5KBW8_CRYNJUncharacterized protein. (363 aa)
Q5KBP9_CRYNJExpressed protein. (374 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. (543 aa)
Q5KBH2_CRYNJUncharacterized protein. (331 aa)
Q5KB94_CRYNJO-methyltransferase, putative. (300 aa)
Q5KAX6_CRYNJrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (325 aa)
Q5KAV0_CRYNJ3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (1030 aa)
Q5KAU8_CRYNJSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (499 aa)
Q5KAS2_CRYNJMethyltranfer_dom domain-containing protein. (277 aa)
Q5KAH5_CRYNJUncharacterized protein. (1020 aa)
Q5KAE4_CRYNJNucleolar essential protein 1, putative. (334 aa)
Q5KAD8_CRYNJMethyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (386 aa)
Q5KA93_CRYNJHomocysteine S-methyltransferase, putative. (381 aa)
Q5KA28_CRYNJtRNA methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (613 aa)
Q5KA00_CRYNJMethyltransferase, putative. (314 aa)
EFM4Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (250 aa)
Q5K9X0_CRYNJProtein kinase domain-containing protein. (1266 aa)
Q5K9U5_CRYNJUPF0020 domain-containing protein. (475 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (344 aa)
Q5K9Q4_CRYNJPolycomb protein e(Z), putative. (729 aa)
Q5K9Q0_CRYNJExpressed protein. (309 aa)
Q5K9D7_CRYNJ5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase, putative. (763 aa)
Q5K948_CRYNJUncharacterized protein. (616 aa)
Q5K945_CRYNJUncharacterized protein. (804 aa)
Q5K943_CRYNJSET domain-containing protein. (1013 aa)
Q5K933_CRYNJUncharacterized protein. (442 aa)
Q5K8X7_CRYNJMTS domain-containing protein. (219 aa)
Q5K8W8_CRYNJNucleus protein, putative. (495 aa)
Q5K8J4_CRYNJPLD phosphodiesterase domain-containing protein. (1001 aa)
Q5K8K7_CRYNJSET domain-containing protein. (776 aa)
Q5K8A7_CRYNJUncharacterized protein. (293 aa)
Q5K870_CRYNJUroporphyrin-III C-methyltransferase, putative. (795 aa)
Q5K829_CRYNJTrans-aconitate 3-methyltransferase, putative. (377 aa)
Q5K7V3_CRYNJUncharacterized protein. (1155 aa)
Q5K7I2_CRYNJUncharacterized protein. (341 aa)
Q5K780_CRYNJUncharacterized protein. (568 aa)
Q5K775_CRYNJIwr1 domain-containing protein. (350 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (286 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (908 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (569 aa)
TMP1Thymidylate synthase. (317 aa)
TRM10tRNA (guanine(9)-N1)-methyltransferase; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family. (429 aa)
TRM61tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. (433 aa)
SET5Potential protein lysine methyltransferase SET5; Putative protein lysine methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily. (449 aa)
RMT2Protein arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. (363 aa)
EFM7Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family. (299 aa)
ABD1mRNA cap guanine-N7 methyltransferase; Responsible for methylating the 5'-cap structure of mRNAs. Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. (700 aa)
PPM1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (398 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (834 aa)
SET1Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. (1469 aa)
DOT1Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone. (644 aa)
A0A0S2M6K2Uncharacterized protein. (205 aa)
A0A0S2M697Methyltransf_11 domain-containing protein. (222 aa)
A0A0S2M5Y1Uncharacterized protein. (240 aa)
A0A0S2LJ70Uncharacterized protein. (274 aa)
A0A0S2LI77Uncharacterized protein. (294 aa)
A0A0S2LI74Protein arginine n-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (342 aa)
Q5KP70_CRYNJExpressed protein. (364 aa)
Q5KPG9_CRYNJProtein phosphatase inhibitor, putative. (325 aa)
Q5KPK4_CRYNJUncharacterized protein. (287 aa)
Q5KPM9_CRYNJUncharacterized protein. (428 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (323 aa)
Q5KQ20_CRYNJtRNA (Guanine-N2-)-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (688 aa)
Q5KN32_CRYNJIMP cyclohydrolase, putative. (120 aa)
EFM6Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (250 aa)
Q5KNA5_CRYNJN2227 domain-containing protein. (448 aa)
Q5KMC0_CRYNJNucleolus protein, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (695 aa)
Q5KNE3_CRYNJPurine nucleotide biosynthesis-related protein, putative. (605 aa)
Q5KNF3_CRYNJUncharacterized protein. (411 aa)
Q5KNM2_CRYNJAspartate carbamoyltransferase, putative. (2333 aa)
Q5KNX3_CRYNJExpressed protein. (223 aa)
Q5KM72_CRYNJPhospholipid metabolism-related protein, putative. (533 aa)
Q5KM39_CRYNJSterol 24-C-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (343 aa)
Q5KM24_CRYNJUncharacterized protein. (236 aa)
Q5KLI5_CRYNJCell division protein, putative. (254 aa)
Q5KLI2_CRYNJrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (510 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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