STRINGSTRING
A0A0S2LII0 A0A0S2LII0 A0A0S2LIJ5 A0A0S2LIJ5 A0A0S2LIL8 A0A0S2LIL8 A0A0S2M5L1 A0A0S2M5L1 A0A0S2M5R0 A0A0S2M5R0 ALG14 ALG14 GET3 GET3 CYN1 CYN1 MDM10 MDM10 MDM12 MDM12 MDM34 MDM34 MMM1 MMM1 NPL4 NPL4 GET1 GET1 Q5K6T9_CRYNJ Q5K6T9_CRYNJ Q5K6Y2_CRYNJ Q5K6Y2_CRYNJ Q5K6Z4_CRYNJ Q5K6Z4_CRYNJ Q5K6Z6_CRYNJ Q5K6Z6_CRYNJ Q5K779_CRYNJ Q5K779_CRYNJ Q5K888_CRYNJ Q5K888_CRYNJ Q5K9Y4_CRYNJ Q5K9Y4_CRYNJ Q5KA71_CRYNJ Q5KA71_CRYNJ Q5KAG9_CRYNJ Q5KAG9_CRYNJ Q5KAJ6_CRYNJ Q5KAJ6_CRYNJ Q5KBP6_CRYNJ Q5KBP6_CRYNJ Q5KBP7_CRYNJ Q5KBP7_CRYNJ Q5KC44_CRYNJ Q5KC44_CRYNJ Q5KC69_CRYNJ Q5KC69_CRYNJ Q5KCF2_CRYNJ Q5KCF2_CRYNJ Q5KCK0_CRYNJ Q5KCK0_CRYNJ Q5KCR0_CRYNJ Q5KCR0_CRYNJ Q5KCS5_CRYNJ Q5KCS5_CRYNJ Q5KCT8_CRYNJ Q5KCT8_CRYNJ Q5KE79_CRYNJ Q5KE79_CRYNJ Q5KEQ0_CRYNJ Q5KEQ0_CRYNJ Q5KEZ5_CRYNJ Q5KEZ5_CRYNJ Q5KEZ7_CRYNJ Q5KEZ7_CRYNJ Q5KFA1_CRYNJ Q5KFA1_CRYNJ Q5KFE4_CRYNJ Q5KFE4_CRYNJ Q5KGN1_CRYNJ Q5KGN1_CRYNJ Q5KIM9_CRYNJ Q5KIM9_CRYNJ Q5KIN5_CRYNJ Q5KIN5_CRYNJ Q5KIW2_CRYNJ Q5KIW2_CRYNJ Q5KIZ1_CRYNJ Q5KIZ1_CRYNJ Q5KJC6_CRYNJ Q5KJC6_CRYNJ Q5KJT1_CRYNJ Q5KJT1_CRYNJ Q5KK05_CRYNJ Q5KK05_CRYNJ Q5KKG9_CRYNJ Q5KKG9_CRYNJ Q5KKW3_CRYNJ Q5KKW3_CRYNJ Q5KKW7_CRYNJ Q5KKW7_CRYNJ Q5KLE1_CRYNJ Q5KLE1_CRYNJ Q5KLI3_CRYNJ Q5KLI3_CRYNJ Q5KM03_CRYNJ Q5KM03_CRYNJ Q5KM88_CRYNJ Q5KM88_CRYNJ Q5KMH4_CRYNJ Q5KMH4_CRYNJ Q5KMQ0_CRYNJ Q5KMQ0_CRYNJ Q5KNA1_CRYNJ Q5KNA1_CRYNJ Q5KNL8_CRYNJ Q5KNL8_CRYNJ Q5KP16_CRYNJ Q5KP16_CRYNJ Q5KP79_CRYNJ Q5KP79_CRYNJ Q5KPR9_CRYNJ Q5KPR9_CRYNJ Q5KQ38_CRYNJ Q5KQ38_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0S2LII0Uncharacterized protein. (90 aa)
A0A0S2LIJ5Uncharacterized protein. (226 aa)
A0A0S2LIL8Uncharacterized protein. (143 aa)
A0A0S2M5L1Uncharacterized protein. (220 aa)
A0A0S2M5R0Uncharacterized protein. (208 aa)
ALG14UDP-N-acetylglucosamine transferase subunit ALG14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER (By similarity). (229 aa)
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (325 aa)
CYN1Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (183 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (508 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (388 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (343 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (475 aa)
NPL4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (693 aa)
GET1Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (215 aa)
Q5K6T9_CRYNJExpressed protein. (475 aa)
Q5K6Y2_CRYNJResponse to unfolded-protein, putative. (277 aa)
Q5K6Z4_CRYNJSignal peptidase subunit 3. (199 aa)
Q5K6Z6_CRYNJUncharacterized protein; Belongs to the heat shock protein 70 family. (733 aa)
Q5K779_CRYNJProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (100 aa)
Q5K888_CRYNJUbiquitin fusion-degradation 1-like protein, putative. (481 aa)
Q5K9Y4_CRYNJUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative. (502 aa)
Q5KA71_CRYNJMMS2, putative; Belongs to the AAA ATPase family. (810 aa)
Q5KAG9_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (468 aa)
Q5KAJ6_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (480 aa)
Q5KBP6_CRYNJLRRNT_2 domain-containing protein. (840 aa)
Q5KBP7_CRYNJUncharacterized protein. (821 aa)
Q5KC44_CRYNJGPI-anchor transamidase, putative. (553 aa)
Q5KC69_CRYNJProtein transporter, putative. (478 aa)
Q5KCF2_CRYNJGPI anchor biosynthesis-related protein, putative. (534 aa)
Q5KCK0_CRYNJRING-type domain-containing protein. (740 aa)
Q5KCR0_CRYNJExpressed protein. (236 aa)
Q5KCS5_CRYNJExpressed protein. (1075 aa)
Q5KCT8_CRYNJUncharacterized protein. (346 aa)
Q5KE79_CRYNJUncharacterized protein. (573 aa)
Q5KEQ0_CRYNJEndoplasmic reticulum protein, putative. (1022 aa)
Q5KEZ5_CRYNJGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (415 aa)
Q5KEZ7_CRYNJUncharacterized protein. (268 aa)
Q5KFA1_CRYNJER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (270 aa)
Q5KFE4_CRYNJUncharacterized protein. (663 aa)
Q5KGN1_CRYNJUbiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family. (175 aa)
Q5KIM9_CRYNJUncharacterized protein. (106 aa)
Q5KIN5_CRYNJ1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (783 aa)
Q5KIW2_CRYNJUncharacterized protein. (250 aa)
Q5KIZ1_CRYNJDolichyl-phosphate-mannose-protein mannosyltransferase, putative. (767 aa)
Q5KJC6_CRYNJUncharacterized protein. (697 aa)
Q5KJT1_CRYNJJ domain-containing protein. (717 aa)
Q5KK05_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (297 aa)
Q5KKG9_CRYNJSignal recognition particle binding protein, putative. (674 aa)
Q5KKW3_CRYNJGlicosidase, putative; Belongs to the glycosyl hydrolase 31 family. (875 aa)
Q5KKW7_CRYNJUncharacterized protein. (175 aa)
Q5KLE1_CRYNJDolichyl-diphosphooligosaccharide-protein glycotransferase, putative. (322 aa)
Q5KLI3_CRYNJAlpha glucosidase, putative; Belongs to the glycosyl hydrolase 31 family. (956 aa)
Q5KM03_CRYNJGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (422 aa)
Q5KM88_CRYNJUncharacterized protein. (865 aa)
Q5KMH4_CRYNJProtein kinase/endoribonuclease, putative. (1073 aa)
Q5KMQ0_CRYNJUncharacterized protein. (335 aa)
Q5KNA1_CRYNJSerine C-palmitoyltransferase, putative. (526 aa)
Q5KNL8_CRYNJUncharacterized protein. (283 aa)
Q5KP16_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (123 aa)
Q5KP79_CRYNJCell division cycle protein 91, putative. (436 aa)
Q5KPR9_CRYNJER membrane protein complex subunit 4; Belongs to the EMC4 family. (197 aa)
Q5KQ38_CRYNJUncharacterized protein. (70 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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