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Q5KN82_CRYNJ Q5KN82_CRYNJ Q5KN20_CRYNJ Q5KN20_CRYNJ Q5KJZ3_CRYNJ Q5KJZ3_CRYNJ Q5KJH4_CRYNJ Q5KJH4_CRYNJ DFR1 DFR1 A0A0S2LHZ7 A0A0S2LHZ7 Q5KJH3_CRYNJ Q5KJH3_CRYNJ Q5KEZ0_CRYNJ Q5KEZ0_CRYNJ Q5KEG6_CRYNJ Q5KEG6_CRYNJ Q5KDF7_CRYNJ Q5KDF7_CRYNJ Q5KDC3_CRYNJ Q5KDC3_CRYNJ Q5KCY2_CRYNJ Q5KCY2_CRYNJ Q5KAU8_CRYNJ Q5KAU8_CRYNJ Q5K8Q9_CRYNJ Q5K8Q9_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q5KN82_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (633 aa)
Q5KN20_CRYNJTransporter, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (386 aa)
Q5KJZ3_CRYNJFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)
Q5KJH4_CRYNJFSH1 domain-containing protein. (301 aa)
DFR1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs to the dihydrofolate reductase family. (229 aa)
A0A0S2LHZ7Uncharacterized protein. (251 aa)
Q5KJH3_CRYNJExpressed protein. (312 aa)
Q5KEZ0_CRYNJMethylenetetrahydrofolate dehydrogenase (NAD+), putative. (367 aa)
Q5KEG6_CRYNJFolic acid and derivative metabolism-related protein, putative. (1021 aa)
Q5KDF7_CRYNJFlavin-adenine dinucleotide transporter, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (339 aa)
Q5KDC3_CRYNJExpressed protein. (967 aa)
Q5KCY2_CRYNJDihydrofolate synthase, putative. (536 aa)
Q5KAU8_CRYNJSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (499 aa)
Q5K8Q9_CRYNJMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (617 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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