STRINGSTRING
A0A0S2LIV9 A0A0S2LIV9 FES1 FES1 NPL4 NPL4 SAR1 SAR1 SEC23 SEC23 SEC24 SEC24 SEC13 SEC13 Q5K6Z6_CRYNJ Q5K6Z6_CRYNJ Q5K710_CRYNJ Q5K710_CRYNJ Q5K745_CRYNJ Q5K745_CRYNJ Q5K766_CRYNJ Q5K766_CRYNJ Q5K779_CRYNJ Q5K779_CRYNJ Q5K7H6_CRYNJ Q5K7H6_CRYNJ Q5K7P2_CRYNJ Q5K7P2_CRYNJ Q5K7R6_CRYNJ Q5K7R6_CRYNJ Q5K7X0_CRYNJ Q5K7X0_CRYNJ Q5K888_CRYNJ Q5K888_CRYNJ Q5K8K4_CRYNJ Q5K8K4_CRYNJ Q5K8W1_CRYNJ Q5K8W1_CRYNJ Q5K913_CRYNJ Q5K913_CRYNJ Q5K950_CRYNJ Q5K950_CRYNJ Q5K9F6_CRYNJ Q5K9F6_CRYNJ Q5KA31_CRYNJ Q5KA31_CRYNJ Q5KA71_CRYNJ Q5KA71_CRYNJ Q5KAB5_CRYNJ Q5KAB5_CRYNJ Q5KAG5_CRYNJ Q5KAG5_CRYNJ Q5KAG9_CRYNJ Q5KAG9_CRYNJ Q5KAJ6_CRYNJ Q5KAJ6_CRYNJ Q5KAZ3_CRYNJ Q5KAZ3_CRYNJ Q5KB79_CRYNJ Q5KB79_CRYNJ Q5KBP7_CRYNJ Q5KBP7_CRYNJ Q5KC49_CRYNJ Q5KC49_CRYNJ Q5KC51_CRYNJ Q5KC51_CRYNJ Q5KC59_CRYNJ Q5KC59_CRYNJ Q5KC69_CRYNJ Q5KC69_CRYNJ Q5KCK0_CRYNJ Q5KCK0_CRYNJ Q5KCK8_CRYNJ Q5KCK8_CRYNJ Q5KCQ0_CRYNJ Q5KCQ0_CRYNJ Q5KDN4_CRYNJ Q5KDN4_CRYNJ Q5KEU0_CRYNJ Q5KEU0_CRYNJ Q5KEW0_CRYNJ Q5KEW0_CRYNJ Q5KEX0_CRYNJ Q5KEX0_CRYNJ Q5KEY4_CRYNJ Q5KEY4_CRYNJ Q5KF72_CRYNJ Q5KF72_CRYNJ Q5KF75_CRYNJ Q5KF75_CRYNJ Q5KFB2_CRYNJ Q5KFB2_CRYNJ Q5KFD4_CRYNJ Q5KFD4_CRYNJ Q5KG79_CRYNJ Q5KG79_CRYNJ Q5KGK7_CRYNJ Q5KGK7_CRYNJ Q5KGN1_CRYNJ Q5KGN1_CRYNJ Q5KH58_CRYNJ Q5KH58_CRYNJ Q5KHB5_CRYNJ Q5KHB5_CRYNJ Q5KHV7_CRYNJ Q5KHV7_CRYNJ Q5KI08_CRYNJ Q5KI08_CRYNJ Q5KI44_CRYNJ Q5KI44_CRYNJ Q5KJT1_CRYNJ Q5KJT1_CRYNJ Q5KJU3_CRYNJ Q5KJU3_CRYNJ Q5KK05_CRYNJ Q5KK05_CRYNJ Q5KKM4_CRYNJ Q5KKM4_CRYNJ Q5KKP4_CRYNJ Q5KKP4_CRYNJ Q5KLE1_CRYNJ Q5KLE1_CRYNJ Q5KLI3_CRYNJ Q5KLI3_CRYNJ Q5KLR7_CRYNJ Q5KLR7_CRYNJ Q5KLW0_CRYNJ Q5KLW0_CRYNJ Q5KM35_CRYNJ Q5KM35_CRYNJ Q5KMH4_CRYNJ Q5KMH4_CRYNJ Q5KMJ4_CRYNJ Q5KMJ4_CRYNJ Q5KMP1_CRYNJ Q5KMP1_CRYNJ Q5KN16_CRYNJ Q5KN16_CRYNJ Q5KN72_CRYNJ Q5KN72_CRYNJ Q5KP16_CRYNJ Q5KP16_CRYNJ Q5KP27_CRYNJ Q5KP27_CRYNJ Q5KPD7_CRYNJ Q5KPD7_CRYNJ Q5KPI7_CRYNJ Q5KPI7_CRYNJ Q5KQ34_CRYNJ Q5KQ34_CRYNJ Q5KQ38_CRYNJ Q5KQ38_CRYNJ Q5KQ46_CRYNJ Q5KQ46_CRYNJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0S2LIV9Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (263 aa)
FES1Hsp70 nucleotide exchange factor FES1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (379 aa)
NPL4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (693 aa)
SAR1Small COPII coat GTPase SAR1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
SEC23Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (763 aa)
SEC24Protein transport protein SEC24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity); Belongs to the SEC23/SEC24 family. SEC24 subfamily. (920 aa)
SEC13Protein transport protein SEC13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (339 aa)
Q5K6Z6_CRYNJUncharacterized protein; Belongs to the heat shock protein 70 family. (733 aa)
Q5K710_CRYNJOTU domain-containing protein. (339 aa)
Q5K745_CRYNJUbiquitin-protein ligase, putative; Belongs to the cullin family. (775 aa)
Q5K766_CRYNJDerlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (219 aa)
Q5K779_CRYNJProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (100 aa)
Q5K7H6_CRYNJProtein disulfide-isomerase. (492 aa)
Q5K7P2_CRYNJUncharacterized protein. (1676 aa)
Q5K7R6_CRYNJChaperone, putative. (700 aa)
Q5K7X0_CRYNJER to Golgi transport-related protein, putative. (1003 aa)
Q5K888_CRYNJUbiquitin fusion-degradation 1-like protein, putative. (481 aa)
Q5K8K4_CRYNJPhospholipase A-2-activating protein, putative. (842 aa)
Q5K8W1_CRYNJU-box domain-containing protein. (1142 aa)
Q5K913_CRYNJChaperone regulator, putative. (369 aa)
Q5K950_CRYNJalpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (940 aa)
Q5K9F6_CRYNJMembrane glycoprotein spo14, putative. (416 aa)
Q5KA31_CRYNJMMS2, putative. (902 aa)
Q5KA71_CRYNJMMS2, putative; Belongs to the AAA ATPase family. (810 aa)
Q5KAB5_CRYNJStructural molecule, putative. (1440 aa)
Q5KAG5_CRYNJPRKCSH domain-containing protein. (536 aa)
Q5KAG9_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (468 aa)
Q5KAJ6_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (480 aa)
Q5KAZ3_CRYNJLectin, putative. (344 aa)
Q5KB79_CRYNJMachado-Joseph disease protein 1 (Ataxin-3), putative. (460 aa)
Q5KBP7_CRYNJUncharacterized protein. (821 aa)
Q5KC49_CRYNJDNA-binding protein. (325 aa)
Q5KC51_CRYNJEukaryotic translation initiation factor 2 alpha subunit, putative. (300 aa)
Q5KC59_CRYNJEndoplasmic reticulum receptor, putative. (305 aa)
Q5KC69_CRYNJProtein transporter, putative. (478 aa)
Q5KCK0_CRYNJRING-type domain-containing protein. (740 aa)
Q5KCK8_CRYNJUncharacterized protein. (570 aa)
Q5KCQ0_CRYNJExpressed protein. (189 aa)
Q5KDN4_CRYNJalpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (864 aa)
Q5KEU0_CRYNJUbiquitin conjugating enzyme, putative. (209 aa)
Q5KEW0_CRYNJEndoplasmic reticulum protein, putative. (445 aa)
Q5KEX0_CRYNJGlycogen metabolism-related protein, putative. (466 aa)
Q5KEY4_CRYNJRING-CH-type domain-containing protein. (1541 aa)
Q5KF72_CRYNJUbiquitin-conjugating enzyme e2-16 kDa, putative; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Q5KF75_CRYNJEndoplasmic reticulum protein, putative. (369 aa)
Q5KFB2_CRYNJExpressed protein. (594 aa)
Q5KFD4_CRYNJUbiquitin-conjugating enzyme E2-28.4KD, putative. (255 aa)
Q5KG79_CRYNJalpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (603 aa)
Q5KGK7_CRYNJUbiquitin conjugating enzyme, putative. (297 aa)
Q5KGN1_CRYNJUbiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family. (175 aa)
Q5KH58_CRYNJCation-transporting ATPase, putative. (780 aa)
Q5KHB5_CRYNJER-associated protein catabolism-related protein, putative. (551 aa)
Q5KHV7_CRYNJHeat shock protein HSP60, putative; Belongs to the heat shock protein 70 family. (601 aa)
Q5KI08_CRYNJCo-chaperone, putative. (522 aa)
Q5KI44_CRYNJEndoplasmic reticulum protein, putative. (203 aa)
Q5KJT1_CRYNJJ domain-containing protein. (717 aa)
Q5KJU3_CRYNJProtein disulfide isomerase, putative. (388 aa)
Q5KK05_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (297 aa)
Q5KKM4_CRYNJChaperone, putative; Belongs to the heat shock protein 70 family. (644 aa)
Q5KKP4_CRYNJHeat shock protein 70, putative; Belongs to the heat shock protein 70 family. (640 aa)
Q5KLE1_CRYNJDolichyl-diphosphooligosaccharide-protein glycotransferase, putative. (322 aa)
Q5KLI3_CRYNJAlpha glucosidase, putative; Belongs to the glycosyl hydrolase 31 family. (956 aa)
Q5KLR7_CRYNJChaperone regulator, putative. (404 aa)
Q5KLW0_CRYNJUncharacterized protein. (896 aa)
Q5KM35_CRYNJUbiquitin-protein ligase, putative. (108 aa)
Q5KMH4_CRYNJProtein kinase/endoribonuclease, putative. (1073 aa)
Q5KMJ4_CRYNJUDP-glucose:glycoprotein glucosyltransferase, putative. (1582 aa)
Q5KMP1_CRYNJUncharacterized protein. (396 aa)
Q5KN16_CRYNJUbiquitin-protein ligase, putative; Belongs to the SKP1 family. (167 aa)
Q5KN72_CRYNJUv excision repair protein rhp23, putative. (406 aa)
Q5KP16_CRYNJDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (123 aa)
Q5KP27_CRYNJEndoplasmic reticulum protein, putative. (557 aa)
Q5KPD7_CRYNJHeat shock protein sks2 (Heat shock cognate protein hsc1), putative; Belongs to the heat shock protein 70 family. (614 aa)
Q5KPI7_CRYNJExpressed protein. (250 aa)
Q5KQ34_CRYNJDisulfide-isomerase, putative; Belongs to the protein disulfide isomerase family. (411 aa)
Q5KQ38_CRYNJUncharacterized protein. (70 aa)
Q5KQ46_CRYNJChaperone regulator, putative. (403 aa)
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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