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PV06_01071 PV06_01071 PV06_06981 PV06_06981 PV06_07657 PV06_07657 PV06_01833 PV06_01833 PV06_08665 PV06_08665 PV06_08927 PV06_08927 PV06_04464 PV06_04464 PV06_11096 PV06_11096 PV06_04900 PV06_04900
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
PV06_01071Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (336 aa)
PV06_069813-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (428 aa)
PV06_07657Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (395 aa)
PV06_01833Elongation of fatty acids protein. (343 aa)
PV06_08665Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (252 aa)
PV06_08927Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (480 aa)
PV06_04464Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (139 aa)
PV06_11096Acyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (174 aa)
PV06_04900Elongation of fatty acids protein. (736 aa)
Your Current Organism:
Exophiala oligosperma
NCBI taxonomy Id: 215243
Other names: CBS 265.49, CBS 725.88, E. oligosperma, Exophiala oligosperma Calendron ex de Hoog & Tintelnot, Exophiala sp. CBS 725.88
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