(38 nodes) Mixed, incl. Inositol catabolic process, and ABC transporter, permease network (Erwinia sp. Ejp617)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	iolE	2-keto-myo-inositol dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family. (359 aa)
	iolG	Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (336 aa)
	iolD	Myo-inositol catabolism protein, malonic semialdehyde oxidative decarboxylase; Belongs to the TPP enzyme family. (646 aa)
	iolC	Myo-inositol catabolism protein. (648 aa)
	iolR	Putative transcriptional regulator. (283 aa)
	iolB	Putative myo-inositol catabolism protein. (277 aa)
	ADP10742.1	Oxidoreductase. (52 aa)
	ADP10795.1	Putative sugar ABC transporter. (352 aa)
	ADP10796.1	Ribose ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (335 aa)
	ADP10797.1	Putative ABC transport system, ATP-binding component. (532 aa)
	ADP10806.1	Transcriptional regulator, LacI family. (341 aa)
	ADP10808.1	Putative epimerase. (249 aa)
	ADP10809.1	Sugar kinase, ribokinase family. (317 aa)
	ADP10810.1	General substrate transporter:Major facilitator superfamily. (428 aa)
	rbsD	D-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (139 aa)
	rbsA	D-ribose transporter ATP binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
	rbsC	Ribose ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (322 aa)
	rbsB	D-ribose transporter subunit RbsB. (293 aa)
	rbsK	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
	rbsR	HTH-type ribose operon repressor rbsR. (333 aa)
	ADP11459.1	Conserved uncharacterized protein. (338 aa)
	yhjK	NTD biosynthesis operon putative hydrolase ntdB. (277 aa)
	ADP11461.1	Putative aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (411 aa)
	araA	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (502 aa)
	araB	Ribulokinase. (563 aa)
	araF	L-arabinose-binding periplasmic protein. (327 aa)
	araG	L-arabinose transporter ATP-binding protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (506 aa)
	araH	L-arabinose transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (326 aa)
	araC	Arabinose operon regulatory protein. (298 aa)
	ydgJ	Putative oxidoreductase. (346 aa)
	araD	L-ribulose-5-phosphate 4-epimerase. (238 aa)
	ADP12803.1	4-hydroxyphenylpyruvate dioxygenase. (300 aa)
	ADP12930.1	Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (174 aa)
	mglC	Beta-methylgalactoside transporter inner membrane component; Belongs to the binding-protein-dependent transport system permease family. (227 aa)
	mglC-2	Beta-methylgalactoside transporter inner membrane component; Belongs to the binding-protein-dependent transport system permease family. (125 aa)
	mglA	Galactoside ABC transport system, ATPase component mglA. (41 aa)
	mglD	HTH-type transcriptional repressor mglD. (339 aa)
	yeiB	Hypothetical protein. (386 aa)

Your Current Organism:

Erwinia sp. Ejp617

NCBI taxonomy Id: 215689
Other names: E. sp. Ejp617

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADP10742.1	ADP10808.1	EJP617_10610	EJP617_11270	Oxidoreductase.	Putative epimerase.	0.615
ADP10742.1	ADP11461.1	EJP617_10610	EJP617_17800	Oxidoreductase.	Putative aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.	0.453
ADP10742.1	ADP12803.1	EJP617_10610	EJP617_31220	Oxidoreductase.	4-hydroxyphenylpyruvate dioxygenase.	0.701
ADP10742.1	iolB	EJP617_10610	EJP617_09830	Oxidoreductase.	Putative myo-inositol catabolism protein.	0.830
ADP10742.1	iolC	EJP617_10610	EJP617_09810	Oxidoreductase.	Myo-inositol catabolism protein.	0.532
ADP10742.1	iolD	EJP617_10610	EJP617_09800	Oxidoreductase.	Myo-inositol catabolism protein, malonic semialdehyde oxidative decarboxylase; Belongs to the TPP enzyme family.	0.837
ADP10742.1	iolE	EJP617_10610	EJP617_09780	Oxidoreductase.	2-keto-myo-inositol dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.	0.645
ADP10795.1	ADP10796.1	EJP617_11140	EJP617_11150	Putative sugar ABC transporter.	Ribose ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family.	0.988
ADP10795.1	ADP10797.1	EJP617_11140	EJP617_11160	Putative sugar ABC transporter.	Putative ABC transport system, ATP-binding component.	0.993
ADP10795.1	ADP10808.1	EJP617_11140	EJP617_11270	Putative sugar ABC transporter.	Putative epimerase.	0.468
ADP10795.1	ADP12930.1	EJP617_11140	EJP617_32490	Putative sugar ABC transporter.	Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.	0.655
ADP10795.1	araG	EJP617_11140	EJP617_28630	Putative sugar ABC transporter.	L-arabinose transporter ATP-binding protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.	0.678
ADP10795.1	araH	EJP617_11140	EJP617_28640	Putative sugar ABC transporter.	L-arabinose transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.	0.655
ADP10795.1	mglD	EJP617_11140	EJP617_33460	Putative sugar ABC transporter.	HTH-type transcriptional repressor mglD.	0.678
ADP10795.1	rbsA	EJP617_11140	EJP617_11890	Putative sugar ABC transporter.	D-ribose transporter ATP binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.	0.678
ADP10795.1	rbsC	EJP617_11140	EJP617_11900	Putative sugar ABC transporter.	Ribose ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.	0.655
ADP10795.1	rbsD	EJP617_11140	EJP617_11880	Putative sugar ABC transporter.	D-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.	0.849
ADP10796.1	ADP10795.1	EJP617_11150	EJP617_11140	Ribose ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family.	Putative sugar ABC transporter.	0.988
ADP10796.1	ADP10797.1	EJP617_11150	EJP617_11160	Ribose ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family.	Putative ABC transport system, ATP-binding component.	0.963
ADP10796.1	araF	EJP617_11150	EJP617_28620	Ribose ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family.	L-arabinose-binding periplasmic protein.	0.667