STRINGSTRING
KGL13967.1 KGL13967.1 rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE rplE rplX rplX rplN rplN rpsQ rpsQ rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ rpsG rpsG rplL rplL rplJ rplJ rplK rplK rpmG rpmG recN recN rpsP rpsP hupB hupB rpsO rpsO rplQ rplQ rpsD rpsD dnaQ dnaQ dnaB dnaB KGL13700.1 KGL13700.1 priA priA rpmI rpmI rplT rplT rplI rplI rpsU rpsU rpsR rpsR KGL12499.1 KGL12499.1 KGL12498.1 KGL12498.1 parB parB rarA rarA KGL12537.1 KGL12537.1 recO recO rpsB rpsB dnaA dnaA KGL12738.1 KGL12738.1 KGL12712.1 KGL12712.1 KGL12709.1 KGL12709.1 KGL12707.1 KGL12707.1 KGL12706.1 KGL12706.1 KGL12703.1 KGL12703.1 KGL12700.1 KGL12700.1 KGL12699.1 KGL12699.1 KGL12698.1 KGL12698.1 KGL12697.1 KGL12697.1 KGL12696.1 KGL12696.1 KGL12695.1 KGL12695.1 KGL12694.1 KGL12694.1 KGL12693.1 KGL12693.1 rpmC rpmC KGL12691.1 KGL12691.1 KGL12690.1 KGL12690.1 rplX-2 rplX-2 KGL12688.1 KGL12688.1 rpsN-2 rpsN-2 KGL12686.1 KGL12686.1 KGL12685.1 KGL12685.1 KGL12684.1 KGL12684.1 KGL12683.1 KGL12683.1 KGL12682.1 KGL12682.1 recR recR rplM rplM rpsI rpsI KGL12969.1 KGL12969.1 KGL12930.1 KGL12930.1 dpnA_4 dpnA_4 mboIIM_2 mboIIM_2 nth nth KGL12912.1 KGL12912.1 KGL12858.1 KGL12858.1 rpmB rpmB spsE spsE KGL13038.1 KGL13038.1 dpnA_3 dpnA_3 KGL13033.1 KGL13033.1 bamHIM_4 bamHIM_4 infB infB KGL13443.1 KGL13443.1 rpmF rpmF guaB guaB rplU rplU rpmA rpmA KGL13503.1 KGL13503.1 rpmH rpmH KGL13315.1 KGL13315.1 KGL13296.1 KGL13296.1 rplY rplY rpmE rpmE yhdJ_6 yhdJ_6 dnaG dnaG rpsT rpsT rpsA rpsA KGL13458.1 KGL13458.1 yhdJ_5 yhdJ_5 KGL13107.1 KGL13107.1 KGL13457.1 KGL13457.1 rplO rplO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KGL13967.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (146 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (181 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (74 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (226 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (118 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (275 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (93 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (204 aa)
rplC50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (155 aa)
rplL50S ribosomal protein L7; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (124 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (162 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
rpmG50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (57 aa)
recNHypothetical protein; May be involved in recombinational repair of damaged DNA. (550 aa)
rpsP30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (76 aa)
hupBDNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial histone-like protein family. (95 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (91 aa)
rplQ50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa)
dnaQHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
dnaBDNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (490 aa)
KGL13700.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (61 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (646 aa)
rpmI50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (149 aa)
rpsU30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family. (70 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (84 aa)
KGL12499.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
KGL12498.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
parBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family. (307 aa)
rarARecombinase RarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
KGL12537.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (177 aa)
recOHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
rpsB30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (275 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (438 aa)
KGL12738.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
KGL12712.150S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology. (57 aa)
KGL12709.150S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
KGL12707.150S ribosomal protein L10; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
KGL12706.150S ribosomal protein L7; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
KGL12703.130S ribosomal protein S7; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
KGL12700.130S ribosomal protein S10; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
KGL12699.150S ribosomal protein L4; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
KGL12698.150S ribosomal protein L23; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
KGL12697.150S ribosomal protein L2; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
KGL12696.130S ribosomal protein S19; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
KGL12695.150S ribosomal protein L22; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
KGL12694.130S ribosomal protein S3; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
KGL12693.150S ribosomal protein L16; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
rpmC50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (65 aa)
KGL12691.130S ribosomal protein S17; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
KGL12690.150S ribosomal protein L14; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
rplX-250S ribosomal protein L24; Assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
KGL12688.150S ribosomal protein L5; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
rpsN-230S ribosomal protein S14; Located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
KGL12686.130S ribosomal protein S8; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
KGL12685.150S ribosomal protein L6; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
KGL12684.150S ribosomal protein L18; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
KGL12683.130S ribosomal protein S5; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
KGL12682.150S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
recRRecombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (193 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (148 aa)
rpsI30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (130 aa)
KGL12969.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (837 aa)
KGL12930.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
dpnA_4DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (261 aa)
mboIIM_2Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (255 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (207 aa)
KGL12912.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (292 aa)
KGL12858.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
rpmB50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. (65 aa)
spsESialic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
KGL13038.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
dpnA_3Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (385 aa)
KGL13033.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
bamHIM_4Restriction endonuclease BamHI; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (318 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (913 aa)
KGL13443.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
rpmF50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. (49 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (243 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (106 aa)
rpmA50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family. (85 aa)
KGL13503.1Ankryin; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
rpmH50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
KGL13315.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
KGL13296.1Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (101 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (178 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (67 aa)
yhdJ_6SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (294 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (550 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (90 aa)
rpsA30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
KGL13458.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
yhdJ_5DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (268 aa)
KGL13107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (60 aa)
KGL13457.1Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (137 aa)
Your Current Organism:
Helicobacter muridarum
NCBI taxonomy Id: 216
Other names: ATCC 49282, CCUG 29262, CIP 104248, DSM 22221, H. muridarum, LMG 13646, LMG:13646, NCTC 12714, strain ST1
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