STRINGSTRING
recJ1 recJ1 albA albA polD2 polD2 cmk cmk BRM9_0381 BRM9_0381 adk adk rnp1 rnp1 BRM9_0543 BRM9_0543 BRM9_0584 BRM9_0584 hfoB hfoB rpoE2 rpoE2 hfoA1 hfoA1 mutS2 mutS2 BRM9_0747 BRM9_0747 BRM9_0805 BRM9_0805 BRM9_0825 BRM9_0825 tiaS tiaS BRM9_0897 BRM9_0897 BRM9_1009 BRM9_1009 BRM9_1063 BRM9_1063 egsA egsA BRM9_1114 BRM9_1114 nucS nucS BRM9_1265 BRM9_1265 BRM9_1370 BRM9_1370 BRM9_1374 BRM9_1374 moaA moaA BRM9_1508 BRM9_1508 BRM9_1603 BRM9_1603 BRM9_1606 BRM9_1606 recJ2 recJ2 BRM9_1620 BRM9_1620 rnp2 rnp2 BRM9_1742 BRM9_1742 BRM9_1803 BRM9_1803 spt5 spt5 pyrE2 pyrE2 BRM9_1917 BRM9_1917 BRM9_1965 BRM9_1965 trpY trpY BRM9_2024 BRM9_2024 BRM9_2236 BRM9_2236 BRM9_2256 BRM9_2256 BRM9_2257 BRM9_2257 BRM9_2262 BRM9_2262 pus10 pus10 rpoF rpoF BRM9_2276 BRM9_2276 BRM9_2278 BRM9_2278 BRM9_2279 BRM9_2279 BRM9_2362 BRM9_2362 BRM9_2384 BRM9_2384
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recJ1ssDNA exonuclease RecJ1. (451 aa)
albADNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (93 aa)
polD2DNA polymerase large subunit DP2 PolD2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1108 aa)
cmkCytidylate kinase Cmk. (176 aa)
BRM9_0381Hypothetical protein. (189 aa)
adkAdenylate kinase Adk; Belongs to the archaeal adenylate kinase family. (185 aa)
rnp1Ribonuclease P subunit P29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (94 aa)
BRM9_0543RNA methyltransferase TrmH family. (230 aa)
BRM9_0584Hydrolase TatD family. (282 aa)
hfoBArchaeal histone B HfoB; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro). (67 aa)
rpoE2DNA-directed RNA polymerase subunit E'' RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (60 aa)
hfoA1Archaeal histone A1 HfoA1; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro). (68 aa)
mutS2DNA mismatch repair ATPase MutS family; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (631 aa)
BRM9_0747Radical SAM domain-containing protein. (363 aa)
BRM9_0805Hypothetical protein. (415 aa)
BRM9_0825HTH domain-containing protein. (318 aa)
tiaSDNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (430 aa)
BRM9_0897tRNA ribose 2'-O-methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (193 aa)
BRM9_1009Archaea-specific RecJ-like exonuclease. (724 aa)
BRM9_1063Hypothetical protein; Belongs to the UPF0179 family. (143 aa)
egsANAD(P)-dependent glycerol-1-phosphate dehydrogenase EgsA; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (348 aa)
BRM9_1114Metallophosphoesterase. (248 aa)
nucSHypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (256 aa)
BRM9_1265Hypothetical protein. (107 aa)
BRM9_1370HTH domain-containing protein. (125 aa)
BRM9_1374Allosteric regulator of homoserine dehydrogenase. (162 aa)
moaAMolybdenum cofactor biosynthesis protein MoaA. (491 aa)
BRM9_1508Hypothetical protein. (441 aa)
BRM9_1603RNA-binding protein. (304 aa)
BRM9_1606DEAD/DEAH box helicase domain-containing protein. (829 aa)
recJ2ssDNA exonuclease RecJ2. (465 aa)
BRM9_1620MarR family transcriptional regulator. (266 aa)
rnp2Ribonuclease P subunit P14; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (125 aa)
BRM9_1742Exosome subunit. (140 aa)
BRM9_1803HD domain-containing protein. (150 aa)
spt5Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (147 aa)
pyrE2Orotate phosphoribosyltransferase PyrE2; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (199 aa)
BRM9_1917Metallo-beta-lactamase superfamily protein; Belongs to the UPF0282 family. (292 aa)
BRM9_1965Hypothetical protein. (136 aa)
trpYTryptophan-binding regulator TrpY. (167 aa)
BRM9_2024Hypothetical protein. (162 aa)
BRM9_2236ArsR family transcriptional regulator. (166 aa)
BRM9_2256Hypothetical protein. (416 aa)
BRM9_2257Hypothetical protein. (257 aa)
BRM9_2262Hypothetical protein. (327 aa)
pus10Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (406 aa)
rpoFDNA-directed RNA polymerase subunit F RpoF. (114 aa)
BRM9_2276RNA-binding protein. (193 aa)
BRM9_2278Carboxymuconolactone decarboxylase family protein. (112 aa)
BRM9_2279SAM-dependent methyltransferase HemK-related protein. (200 aa)
BRM9_2362Hypothetical protein. (218 aa)
BRM9_2384Hypothetical protein; Belongs to the UPF0147 family. (84 aa)
Your Current Organism:
Methanobacterium formicicum
NCBI taxonomy Id: 2162
Other names: ATCC 33274, JCM 10132, M. formicicum, Methanobacterium sp. BRM9, NBRC 100475, OCM 55, strain MF
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