40 items (Metschnikowia aff.) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MPUL0C08750	Checkpoint protein; Belongs to the HUS1 family. (313 aa)
	MPUL0A00760	COMPASS component BRE2. (515 aa)
	MPUL0A08890	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (337 aa)
	MPUL0A10940	Pore complex protein Nup133. (1145 aa)
	MPUL0A13880	Origin recognition complex subunit 6. (396 aa)
	MPUL0B00320	KH domain-containing protein. (1204 aa)
	MPUL0A02380	DNA helicase; Belongs to the MCM family. (845 aa)
	MPUL0B02040	DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR). (990 aa)
	MPUL0A02950	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (781 aa)
	MPUL0B04890	Ran GTPase-activating protein 1. (414 aa)
	MPUL0A11270	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (405 aa)
	MPUL0B05520	Origin recognition complex subunit 3. (763 aa)
	MPUL0A06120	DNA helicase; Belongs to the MCM family. (728 aa)
	MPUL0B08790	Myb-like DNA-binding protein RAP1. (609 aa)
	METSCH_A12610	GATA-type domain-containing protein. (765 aa)
	METSCH_B04090	ANK_REP_REGION domain-containing protein. (1120 aa)
	MPUL0A07290	Regulator of nonsense transcripts 1. (985 aa)
	MPUL0B00570	Minichromosome maintenance protein 10. (605 aa)
	MPUL0A09410	WSTF, HB1, Itc1p, MBD9 motif 1. (1197 aa)
	MPUL0B12250	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (417 aa)
	MPUL0C01050	COMPASS component SWD1. (437 aa)
	MPUL0B11530	NAD-dependent histone deacetylase SIR2. (473 aa)
	MPUL0B05400	Origin recognition complex subunit 5. (568 aa)
	MPUL0C07630	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (788 aa)
	MPUL0B06100	Nicotinamidase. (284 aa)
	MPUL0C07880	COMPASS component SPP1. (382 aa)
	MPUL0C02550	Nucleoporin NUP145. (1313 aa)
	MPUL0C03150	Pore complex protein Nup160. (1142 aa)
	MPUL0D00510	Mediator of replication checkpoint protein 1. (1068 aa)
	MPUL0B08610	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (247 aa)
	MPUL0C02220	Ubiquitin-conjugating enzyme E2 A/ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	MPUL0C03270	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	METSCH_E04440	Uncharacterized protein. (661 aa)
	MPUL0D08520	Ras-related GTP-binding protein A/B. (330 aa)
	MPUL0E01090	Ubiquitin carboxyl-terminal hydrolase 10; Belongs to the peptidase C19 family. (739 aa)
	MPUL0D00940	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1148 aa)
	MPUL0F01800	Origin recognition complex subunit 4. (748 aa)
	MPUL0G00140	SWI/SNF-related. (1044 aa)
	MPUL0B04130	Histone H2A; Belongs to the histone H2A family. (133 aa)
	MPUL0D03830	Ubiquitin-2 like Rad60 SUMO-like. (437 aa)

Your Current Organism:

Metschnikowia aff.

NCBI taxonomy Id: 2163413
Other names: M. aff. pulcherrima, Metschnikowia aff. pulcherrima

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
METSCH_E04440	MPUL0B04130	A0A4P6XRL7	A0A4V1ADX3	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.625
MPUL0A00760	MPUL0B04130	A0A4P6XCY1	A0A4V1ADX3	COMPASS component BRE2.	Histone H2A; Belongs to the histone H2A family.	0.781
MPUL0A00760	MPUL0C01050	A0A4P6XCY1	A0A4P6XL88	COMPASS component BRE2.	COMPASS component SWD1.	0.999
MPUL0A00760	MPUL0C07880	A0A4P6XCY1	A0A4P6XN27	COMPASS component BRE2.	COMPASS component SPP1.	0.989
MPUL0A02380	MPUL0A02950	A0A4P6XHU4	A0A4P6XJ32	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MPUL0A02380	MPUL0A06120	A0A4P6XHU4	A0A4P6XJZ9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MPUL0A02380	MPUL0A13880	A0A4P6XHU4	A0A4P6XHI4	DNA helicase; Belongs to the MCM family.	Origin recognition complex subunit 6.	0.892
MPUL0A02380	MPUL0B00570	A0A4P6XHU4	A0A4P6XL24	DNA helicase; Belongs to the MCM family.	Minichromosome maintenance protein 10.	0.989
MPUL0A02380	MPUL0B05400	A0A4P6XHU4	A0A4P6XMU8	DNA helicase; Belongs to the MCM family.	Origin recognition complex subunit 5.	0.991
MPUL0A02380	MPUL0B05520	A0A4P6XHU4	A0A4P6XJI8	DNA helicase; Belongs to the MCM family.	Origin recognition complex subunit 3.	0.947
MPUL0A02380	MPUL0C03270	A0A4P6XHU4	A0A4P6XR49	DNA helicase; Belongs to the MCM family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.903
MPUL0A02380	MPUL0D00510	A0A4P6XHU4	A0A4P6XND7	DNA helicase; Belongs to the MCM family.	Mediator of replication checkpoint protein 1.	0.747
MPUL0A02380	MPUL0D00940	A0A4P6XHU4	A0A4P6XT49	DNA helicase; Belongs to the MCM family.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.416
MPUL0A02380	MPUL0F01800	A0A4P6XHU4	A0A4P6XVM1	DNA helicase; Belongs to the MCM family.	Origin recognition complex subunit 4.	0.986
MPUL0A02950	MPUL0A02380	A0A4P6XJ32	A0A4P6XHU4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MPUL0A02950	MPUL0A06120	A0A4P6XJ32	A0A4P6XJZ9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MPUL0A02950	MPUL0A13880	A0A4P6XJ32	A0A4P6XHI4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Origin recognition complex subunit 6.	0.886
MPUL0A02950	MPUL0B00570	A0A4P6XJ32	A0A4P6XL24	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Minichromosome maintenance protein 10.	0.993
MPUL0A02950	MPUL0B02040	A0A4P6XJ32	A0A4P6XIL4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR).	0.404
MPUL0A02950	MPUL0B04130	A0A4P6XJ32	A0A4V1ADX3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Histone H2A; Belongs to the histone H2A family.	0.432