node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MPUL0A08620 | MPUL0A12640 | A0A4P6XJG0 | A0A4P6XJ00 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | 0.909 |
MPUL0A08620 | MPUL0B08610 | A0A4P6XJG0 | A0A4P6XPL9 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.984 |
MPUL0A08620 | MPUL0C02260 | A0A4P6XJG0 | A0A4P6XLX5 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | HPC2 and ubinuclein domain-containing protein. | 0.927 |
MPUL0A08620 | MPUL0D00860 | A0A4P6XJG0 | A0A4P6XRQ0 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Helicase SWR1. | 0.494 |
MPUL0A08620 | MPUL0D04620 | A0A4P6XJG0 | A0A4P6XTP4 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Histone H2B; Belongs to the histone H2B family. | 0.433 |
MPUL0A09480 | MPUL0B10430 | A0A4P6XKU5 | A0A4P6XKR7 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.790 |
MPUL0A09480 | MPUL0C04050 | A0A4P6XKU5 | A0A4P6XM62 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | DNA repair protein RAD50. | 0.974 |
MPUL0A09480 | MPUL0D04620 | A0A4P6XKU5 | A0A4P6XTP4 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Histone H2B; Belongs to the histone H2B family. | 0.512 |
MPUL0A09480 | MPUL0D07210 | A0A4P6XKU5 | A0A4P6XUB9 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.985 |
MPUL0A12640 | MPUL0A08620 | A0A4P6XJ00 | A0A4P6XJG0 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | 0.909 |
MPUL0A12640 | MPUL0B08610 | A0A4P6XJ00 | A0A4P6XPL9 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.949 |
MPUL0A12640 | MPUL0C02260 | A0A4P6XJ00 | A0A4P6XLX5 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | HPC2 and ubinuclein domain-containing protein. | 0.882 |
MPUL0A12640 | MPUL0D00860 | A0A4P6XJ00 | A0A4P6XRQ0 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Helicase SWR1. | 0.494 |
MPUL0A12640 | MPUL0D04620 | A0A4P6XJ00 | A0A4P6XTP4 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | Histone H2B; Belongs to the histone H2B family. | 0.430 |
MPUL0B08610 | MPUL0A08620 | A0A4P6XPL9 | A0A4P6XJG0 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | 0.984 |
MPUL0B08610 | MPUL0A12640 | A0A4P6XPL9 | A0A4P6XJ00 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. | 0.949 |
MPUL0B08610 | MPUL0B10430 | A0A4P6XPL9 | A0A4P6XKR7 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.430 |
MPUL0B08610 | MPUL0C02260 | A0A4P6XPL9 | A0A4P6XLX5 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | HPC2 and ubinuclein domain-containing protein. | 0.875 |
MPUL0B08610 | MPUL0D00860 | A0A4P6XPL9 | A0A4P6XRQ0 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Helicase SWR1. | 0.554 |
MPUL0B08610 | MPUL0D04620 | A0A4P6XPL9 | A0A4P6XTP4 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Histone H2B; Belongs to the histone H2B family. | 0.515 |