STRINGSTRING
MMAR_0132 MMAR_0132 eis1 eis1 esxB_1 esxB_1 esxA_1 esxA_1 esxA_3 esxA_3 esxB_2 esxB_2 esxA_2 esxA_2 aac aac pinR pinR MMAR_0677 MMAR_0677 MMAR_1161 MMAR_1161 MMAR_1162 MMAR_1162 MMAR_1216 MMAR_1216 MMAR_1421 MMAR_1421 devR devR serB2 serB2 MMAR_2129 MMAR_2129 MMAR_2137 MMAR_2137 MMAR_2144 MMAR_2144 tlyA tlyA MMAR_2522 MMAR_2522 MMAR_2944 MMAR_2944 MMAR_3124 MMAR_3124 MMAR_3147 MMAR_3147 MMAR_3227 MMAR_3227 ptpA ptpA MMAR_3424 MMAR_3424 MMAR_3480 MMAR_3480 MMAR_3592 MMAR_3592 eis eis MMAR_3959 MMAR_3959 MMAR_4142 MMAR_4142 MMAR_4223 MMAR_4223 MMAR_4224 MMAR_4224 MMAR_4377 MMAR_4377 MMAR_4432 MMAR_4432 MMAR_4443 MMAR_4443 MMAR_4560 MMAR_4560 MMAR_4602 MMAR_4602 narL narL MMAR_4995 MMAR_4995 MMAR_5099 MMAR_5099 ppa ppa MMAR_5321 MMAR_5321 MMAR_5322 MMAR_5322 esxB esxB esxA esxA MMAR_5464 MMAR_5464
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMAR_0132Response regulator of a two-component regulatory system involved in transcriptional regulatory mechanism. has domain homology to CitB, a response regulator containing a CheY-like receiver domain and an HTH DNA- binding domain. (220 aa)
eis1Enhanced intracellular survival protein Eis1; Supposed involved in intracellular survival. possibly associated with the cell surface and secreted. (405 aa)
esxB_1A culture filtrate antigen that forms part of a novel secretion apparatus; Belongs to the WXG100 family. (100 aa)
esxA_16 kDa culture filtrate antigen EsxA_1 (early secreted antigenic target - Esat6); 6kDA, culture filtrate antigen forms part of a novel secretion apparatus; Belongs to the WXG100 family. (95 aa)
esxA_3Conserved hypothetical EsxA-like protein, EsxA_3; Function unknown but identity with other Esx proteins, including EsxA; Belongs to the WXG100 family. (95 aa)
esxB_2Conserved hypothetical EsxB-like protein, EsxB_2; Belongs to the WXG100 family. (100 aa)
esxA_2Conserved hypothetical EsxA-like protein, EsxA_2; Belongs to the WXG100 family. (95 aa)
aacAminoglycoside 2'-N-acetyltransferase Aac; Confers resistance to aminoglycosides (gentamicin, tobramycin, dibekacin, netilmicin, and 6'-N- ethylnetilmicin). (181 aa)
pinRSite-specific recombinase PinR; Possible phage recombinase. (200 aa)
MMAR_0677Efflux membrane protein; Possibly involved in export of metal ions across the membrane. (307 aa)
MMAR_1161PE-PGRS family protein. (594 aa)
MMAR_1162PE-PGRS family protein. (593 aa)
MMAR_1216Acid phosphatase; Involved in cellular metabolism: acting on ester bonds [catalytic activity: an orthophosphoric monoester + H(2)O = an alcohol + orthophosphate]. (295 aa)
MMAR_1421Transposase for insertion sequence; Single copy element. (86 aa)
devRRegulator part of the two-component regulatory system DevR/DevS. controls HspX|Acr expression. (216 aa)
serB2Phosphoserine phosphatase SerB2; Generates serine from phosphoserine [catalytic activity: phosphoserine + H(2)O = serine + phosphate]. (411 aa)
MMAR_2129Site-specific integrase; DNA integration - phage mediated. (479 aa)
MMAR_2137Conserved hypothetical metal transport protein; Function unknown; possibly involved in transport of metal ions across the membrane. (329 aa)
MMAR_2144Conserved hypothetical membrane protein; Function unknown; possibly involved in transport of metal ions across the membrane. (305 aa)
tlyACytotoxin/hemolysin, TlyA; Has a contact-dependent haemolytic activity; possibly involved in virulence (pore formation). (281 aa)
MMAR_2522Conserved hypothetical protein. (220 aa)
MMAR_2944PPE family protein. (569 aa)
MMAR_3124Integrase; Site-specific integration of bacteriophage DNA. (548 aa)
MMAR_3147Conserved hypothetical membrane protein. (360 aa)
MMAR_3227Conserved hypothetical protein. (129 aa)
ptpAPhosphotyrosine protein phosphatase PtpA; Involved in signal transduction (via dephosphorylation). can dephosphorylated in vitro the phosphotyrosine residue of myelin basic protein (MBP) at ph 7.0 [catalytic activity: protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (164 aa)
MMAR_3424PE-PGRS family protein, PE_PGRS22. (454 aa)
MMAR_3480Regulator part of a two-component regulatory system. (217 aa)
MMAR_3592Hypothetical protein. (52 aa)
eisEnhanced intracellular survival protein Eis; Supposed involved in intracellular survival. possibly associated with the cell surface and secreted. (397 aa)
MMAR_3959Regulator part of the two-component regulatory system. (218 aa)
MMAR_4142Conserved hydrolase; Function unknown, contains P-loop containing nucleoside triphosphate hydrolase superfamily domain. (876 aa)
MMAR_4223PE-PGRS family protein. (602 aa)
MMAR_4224PE-PGRS family protein. (598 aa)
MMAR_4377PE-PGRS family protein. (509 aa)
MMAR_4432Conserved hypothetical protein. (233 aa)
MMAR_4443Site-specific recombinase; Phage DNA recombination function. (220 aa)
MMAR_4560PE-PGRS family protein. (353 aa)
MMAR_4602PE-PGRS family protein. (1251 aa)
narLNitrate/nitrite response regulator protein NarL. (216 aa)
MMAR_4995PE-PGRS family protein. (1408 aa)
MMAR_5099PE-PGRS family protein. (456 aa)
ppaInorganic pyrophosphatase Ppa; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (162 aa)
MMAR_5321PE-PGRS family protein. (723 aa)
MMAR_5322PE-PGRS family protein. (493 aa)
esxBEsat-6 like protein EsxB; Function unknown; a component of a novel secretion apparatus. (10 kDa culture filtrate antigen cfp10). (100 aa)
esxA6 kDa early secretory antigenic target EsxA (EsaT-6); Function unknown; probably a component of a novel secretion mechanism. forms a heterodimer with EsxB; Belongs to the WXG100 family. (95 aa)
MMAR_5464ADP-ribosyltransferse; Related to a family of actin-ADP-ribosylating toxins from bacillus and clostridia hence may play a role in virulence or protection against predation. (806 aa)
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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