(5 nodes) Tryptophan biosynthesis network (Shigella sonnei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	trpE	Unannotated protein. (520 aa)
	trpD	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa)
	trpF	Unannotated protein; Belongs to the TrpC family. (452 aa)
	trpB	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
	trpA	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)

Your Current Organism:

Shigella sonnei

NCBI taxonomy Id: 216599
Other names: S. sonnei 53G, Shigella sonnei 53G, Shigella sonnei str. 53G

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
trpA	trpB	GCA_000283715_02141	GCA_000283715_02140	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.999
trpA	trpD	GCA_000283715_02141	GCA_000283715_02138	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.998
trpA	trpE	GCA_000283715_02141	GCA_000283715_02137	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Unannotated protein.	0.993
trpA	trpF	GCA_000283715_02141	GCA_000283715_02139	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	Unannotated protein; Belongs to the TrpC family.	0.999
trpB	trpA	GCA_000283715_02140	GCA_000283715_02141	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.999
trpB	trpD	GCA_000283715_02140	GCA_000283715_02138	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.999
trpB	trpE	GCA_000283715_02140	GCA_000283715_02137	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	Unannotated protein.	0.994
trpB	trpF	GCA_000283715_02140	GCA_000283715_02139	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	Unannotated protein; Belongs to the TrpC family.	0.999
trpD	trpA	GCA_000283715_02138	GCA_000283715_02141	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.998
trpD	trpB	GCA_000283715_02138	GCA_000283715_02140	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.999
trpD	trpE	GCA_000283715_02138	GCA_000283715_02137	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	Unannotated protein.	0.999
trpD	trpF	GCA_000283715_02138	GCA_000283715_02139	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	Unannotated protein; Belongs to the TrpC family.	0.999
trpE	trpA	GCA_000283715_02137	GCA_000283715_02141	Unannotated protein.	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.993
trpE	trpB	GCA_000283715_02137	GCA_000283715_02140	Unannotated protein.	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.994
trpE	trpD	GCA_000283715_02137	GCA_000283715_02138	Unannotated protein.	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.999
trpE	trpF	GCA_000283715_02137	GCA_000283715_02139	Unannotated protein.	Unannotated protein; Belongs to the TrpC family.	0.999
trpF	trpA	GCA_000283715_02139	GCA_000283715_02141	Unannotated protein; Belongs to the TrpC family.	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.999
trpF	trpB	GCA_000283715_02139	GCA_000283715_02140	Unannotated protein; Belongs to the TrpC family.	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.999
trpF	trpD	GCA_000283715_02139	GCA_000283715_02138	Unannotated protein; Belongs to the TrpC family.	Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.999
trpF	trpE	GCA_000283715_02139	GCA_000283715_02137	Unannotated protein; Belongs to the TrpC family.	Unannotated protein.	0.999