STRINGSTRING
cpxA cpxA coaA coaA zraS zraS GCA_000283715_04728 GCA_000283715_04728 GCA_000283715_04729 GCA_000283715_04729 manX_2 manX_2 dgkA dgkA BZ172_13945 BZ172_13945 yjdH yjdH GCA_000283715_04929 GCA_000283715_04929 GCA_000283715_04930 GCA_000283715_04930 ulaB ulaB treB treB idnK idnK nadR nadR creC creC wzz wzz GCA_000283715_04651 GCA_000283715_04651 GCA_000283715_04650 GCA_000283715_04650 BZ172_12945 BZ172_12945 glpK glpK pfkA pfkA manP manP rhaB rhaB frvA frvA BZ172_12625 BZ172_12625 rbsK_1 rbsK_1 glnL glnL rdoA rdoA ubiB ubiB rbsK rbsK bglF bglF kdgK kdgK GCA_000283715_04279 GCA_000283715_04279 mtlA_1 mtlA_1 uhpB uhpB glvC glvC dgoK dgoK gntK gntK envZ envZ aroK aroK frlD frlD cfxP cfxP slyX slyX yhcI yhcI arcB arcB BZ172_08060 BZ172_08060 ptsN ptsN garK garK hldE hldE qseC qseC mtlA_2 mtlA_2 fucK fucK barA barA GCA_000283715_03333 GCA_000283715_03333 cysC cysC BZ172_05160 BZ172_05160 ascF ascF srlB srlB srlE srlE ppnK ppnK BZ172_03665 BZ172_03665 BZ172_03165 BZ172_03165 BZ172_03005 BZ172_03005 pdxK pdxK glk glk fryB_2 fryB_2 fryC fryC BZ172_02770 BZ172_02770 evgS evgS GCA_000283715_02772 GCA_000283715_02772 BZ172_02635 BZ172_02635 atoS atoS rcsC rcsC yojN yojN fruK fruK fruA fruA psuK_1 psuK_1 psuK_2 psuK_2 yehU yehU thiM thiM iolC iolC gatB gatB yegS yegS baeS baeS BZ172_00560 BZ172_00560 udk udk wzc wzc BZ172_00210 BZ172_00210 yedV yedV ipk ipk GCA_000283715_02243 GCA_000283715_02243 narX narX rstB rstB GCA_000283715_01751 GCA_000283715_01751 malX malX ydgK ydgK pdxY pdxY anmK anmK pykF pykF ydiA ydiA pfkB pfkB chbC chbC chbB chbB BZ172_24065 BZ172_24065 manX_3 manX_3 pykA pykA cheA cheA phoQ phoQ thiK thiK ptsG ptsG BZ172_21590 BZ172_21590 etk1 etk1 lpxK lpxK ybhK ybhK galK galK BZ172_19610 BZ172_19610 kdpD kdpD nagE nagE dpiB dpiB fepE fepE BZ172_18660 BZ172_18660 gsk gsk phoR phoR mak mak aroL aroL coaE coaE araB araB BZ172_15740 BZ172_15740 thrB thrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cpxAUnannotated protein. (457 aa)
coaAUnannotated protein. (308 aa)
zraSUnannotated protein. (458 aa)
GCA_000283715_04728Unannotated protein. (73 aa)
GCA_000283715_04729Unannotated protein. (74 aa)
manX_2Unannotated protein. (135 aa)
dgkAUnannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
BZ172_13945Unannotated protein. (366 aa)
yjdHUnannotated protein. (543 aa)
GCA_000283715_04929Unannotated protein. (101 aa)
GCA_000283715_04930Unannotated protein. (375 aa)
ulaBUnannotated protein. (101 aa)
treBUnannotated protein. (473 aa)
idnKUnannotated protein. (187 aa)
nadRUnannotated protein. (410 aa)
creCUnannotated protein. (474 aa)
wzzUnannotated protein. (368 aa)
GCA_000283715_04651Unannotated protein. (48 aa)
GCA_000283715_04650Unannotated protein. (39 aa)
BZ172_12945Unannotated protein. (359 aa)
glpKUnannotated protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (503 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
manPUnannotated protein. (113 aa)
rhaBUnannotated protein; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (489 aa)
frvAUnannotated protein. (148 aa)
BZ172_12625Unannotated protein. (483 aa)
rbsK_1Unannotated protein; Belongs to the carbohydrate kinase PfkB family. (267 aa)
glnLUnannotated protein. (349 aa)
rdoAUnannotated protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa)
ubiBUnannotated protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (546 aa)
rbsKUnannotated protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
bglFUnannotated protein. (625 aa)
kdgKUnannotated protein. (309 aa)
GCA_000283715_04279Unannotated protein. (484 aa)
mtlA_1Unannotated protein. (637 aa)
uhpBUnannotated protein. (500 aa)
glvCUnannotated protein. (538 aa)
dgoKUnannotated protein. (292 aa)
gntKUnannotated protein. (175 aa)
envZUnannotated protein. (450 aa)
aroKUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
frlDUnannotated protein. (261 aa)
cfxPUnannotated protein. (289 aa)
slyXUnannotated protein; Belongs to the SlyX family. (72 aa)
yhcIUnannotated protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (291 aa)
arcBUnannotated protein. (778 aa)
BZ172_08060Unannotated protein. (210 aa)
ptsNUnannotated protein. (163 aa)
garKUnannotated protein; Belongs to the glycerate kinase type-1 family. (381 aa)
hldEUnannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)
qseCUnannotated protein. (449 aa)
mtlA_2Unannotated protein. (337 aa)
fucKUnannotated protein; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (472 aa)
barAUnannotated protein. (918 aa)
GCA_000283715_03333Unannotated protein. (496 aa)
cysCUnannotated protein; Catalyzes the synthesis of activated sulfate. (201 aa)
BZ172_05160Unannotated protein. (117 aa)
ascFUnannotated protein. (485 aa)
srlBUnannotated protein. (123 aa)
srlEUnannotated protein. (319 aa)
ppnKUnannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa)
BZ172_03665Unannotated protein. (460 aa)
BZ172_03165Unannotated protein. (566 aa)
BZ172_03005Unannotated protein. (412 aa)
pdxKUnannotated protein; B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i.e. PNP, PLP and PMP. (283 aa)
glkUnannotated protein; Belongs to the bacterial glucokinase family. (321 aa)
fryB_2Unannotated protein. (108 aa)
fryCUnannotated protein. (415 aa)
BZ172_02770Unannotated protein. (565 aa)
evgSUnannotated protein. (1197 aa)
GCA_000283715_02772Unannotated protein. (162 aa)
BZ172_02635Unannotated protein. (74 aa)
atoSUnannotated protein. (597 aa)
rcsCUnannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (949 aa)
yojNUnannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (890 aa)
fruKUnannotated protein; Belongs to the carbohydrate kinase PfkB family. (312 aa)
fruAUnannotated protein. (563 aa)
psuK_1Unannotated protein. (313 aa)
psuK_2Unannotated protein. (362 aa)
yehUUnannotated protein. (561 aa)
thiMUnannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (262 aa)
iolCUnannotated protein; Belongs to the carbohydrate kinase PfkB family. (321 aa)
gatBUnannotated protein. (94 aa)
yegSUnannotated protein; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (299 aa)
baeSUnannotated protein. (467 aa)
BZ172_00560Unannotated protein. (646 aa)
udkUnannotated protein. (213 aa)
wzcUnannotated protein. (720 aa)
BZ172_00210Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa)
yedVUnannotated protein; Member of a two-component regulatory system. (452 aa)
ipkUnannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (283 aa)
GCA_000283715_02243Unannotated protein. (269 aa)
narXUnannotated protein. (598 aa)
rstBUnannotated protein. (433 aa)
GCA_000283715_01751Unannotated protein. (380 aa)
malXUnannotated protein. (530 aa)
ydgKUnannotated protein. (146 aa)
pdxYUnannotated protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (286 aa)
anmKUnannotated protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa)
pykFUnannotated protein; Belongs to the pyruvate kinase family. (470 aa)
ydiAUnannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (277 aa)
pfkBUnannotated protein; Belongs to the carbohydrate kinase PfkB family. (309 aa)
chbCUnannotated protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
chbBUnannotated protein. (106 aa)
BZ172_24065Unannotated protein. (644 aa)
manX_3Unannotated protein. (323 aa)
pykAUnannotated protein; Belongs to the pyruvate kinase family. (480 aa)
cheAUnannotated protein. (654 aa)
phoQUnannotated protein. (486 aa)
thiKUnannotated protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (274 aa)
ptsGUnannotated protein. (477 aa)
BZ172_21590Unannotated protein. (899 aa)
etk1Unannotated protein. (726 aa)
lpxKUnannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (328 aa)
ybhKUnannotated protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (302 aa)
galKUnannotated protein; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (382 aa)
BZ172_19610Unannotated protein. (638 aa)
kdpDUnannotated protein. (894 aa)
nagEUnannotated protein. (648 aa)
dpiBUnannotated protein. (552 aa)
fepEUnannotated protein. (377 aa)
BZ172_18660Unannotated protein; Member of a two-component regulatory system. (482 aa)
gskUnannotated protein. (434 aa)
phoRUnannotated protein. (431 aa)
makUnannotated protein. (302 aa)
aroLUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa)
coaEUnannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa)
araBUnannotated protein. (566 aa)
BZ172_15740Unannotated protein; Belongs to the ribF family. (313 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa)
Your Current Organism:
Shigella sonnei
NCBI taxonomy Id: 216599
Other names: S. sonnei 53G, Shigella sonnei 53G, Shigella sonnei str. 53G
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