STRINGSTRING
fbpC2 fbpC2 lolD_2 lolD_2 fepC fepC artP artP GCA_000283715_00674 GCA_000283715_00674 GCA_000283715_00723 GCA_000283715_00723 modF modF modC modC dnaC_3 dnaC_3 ybhF_2 ybhF_2 glnQ glnQ yheS_1 yheS_1 BZ172_20435 BZ172_20435 potG potG artP-2 artP-2 ybjZ ybjZ clpA clpA cudC cudC cydD cydD rarA rarA msbA msbA ssuB ssuB BZ172_21305 BZ172_21305 GCA_000283715_01097 GCA_000283715_01097 GCA_000283715_01111 GCA_000283715_01111 lolD_1 lolD_1 potA_1 potA_1 yecC yecC GCA_000283715_01259 GCA_000283715_01259 araG araG GCA_000283715_01317 GCA_000283715_01317 ruvB ruvB znuC znuC GCA_000283715_01456 GCA_000283715_01456 btuD btuD sufC sufC GCA_000283715_01688 GCA_000283715_01688 GCA_000283715_01740 GCA_000283715_01740 GCA_000283715_01759 GCA_000283715_01759 BZ172_25170 BZ172_25170 BZ172_26045 BZ172_26045 gsiA_4 gsiA_4 GCA_000283715_01883 GCA_000283715_01883 potA_2 potA_2 hrpA hrpA sitB_2 sitB_2 BZ172_25330 BZ172_25330 tyrR tyrR ugpC_2 ugpC_2 pspF pspF sapD sapD sapF sapF oppF oppF oppD oppD fliI fliI proV_1 proV_1 mglA mglA gsiA_1 gsiA_1 BZ172_01310 BZ172_01310 ccmA ccmA yojI yojI zraR_2 zraR_2 hisP hisP GCA_000283715_02762 GCA_000283715_02762 cysA cysA fhlA_1 fhlA_1 yphE yphE qseF_1 qseF_1 GCA_000283715_03055 GCA_000283715_03055 GCA_000283715_03074 GCA_000283715_03074 clpB clpB GCA_000283715_03160 GCA_000283715_03160 proV_2 proV_2 recA recA ygaA ygaA GCA_000283715_03279 GCA_000283715_03279 recD recD BZ172_05995 BZ172_05995 ecfA1_2 ecfA1_2 ecfA1_1 ecfA1_1 yggR_3 yggR_3 GCA_000283715_03745 GCA_000283715_03745 hflB hflB mlaF mlaF lptB lptB artM_2 artM_2 GCA_000283715_03896 GCA_000283715_03896 yheS_2 yheS_2 ugpC_1 ugpC_1 livF livF livG livG ftsE ftsE nikD nikD nikE nikE ybhF_1 ybhF_1 GCA_000283715_04080 GCA_000283715_04080 dnaA dnaA GCA_000283715_04195 GCA_000283715_04195 dppD dppD dppF dppF atpD atpD ravA ravA pstB pstB rbsA rbsA GCA_000283715_04399 GCA_000283715_04399 rho rho glnG glnG hslU hslU GCA_000283715_04633 GCA_000283715_04633 zraR_1 zraR_1 malK malK dnaB_1 dnaB_1 phnL phnL phnK phnK phnC phnC ytfR ytfR GCA_000283715_04996 GCA_000283715_04996 fecE fecE dnaC_1 dnaC_1 radA radA yjjK yjjK GCA_000283715_05159 GCA_000283715_05159 spaL spaL GCA_000283715_05253 GCA_000283715_05253 GCA_000283715_05265 GCA_000283715_05265 GCA_000283715_05291 GCA_000283715_05291 BZ172_30355 BZ172_30355 BZ172_02585 BZ172_02585 thiQ thiQ gspE_3 gspE_3 drrA drrA fhuC fhuC metN_2 metN_2 GCA_000283715_00245 GCA_000283715_00245 BZ172_19440 BZ172_19440 tauB tauB lon lon mdlA mdlA mdlB mdlB dnaX dnaX ybbL ybbL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbpC2Unannotated protein. (217 aa)
lolD_2Unannotated protein. (228 aa)
fepCUnannotated protein. (271 aa)
artPUnannotated protein. (241 aa)
GCA_000283715_00674Unannotated protein. (251 aa)
GCA_000283715_00723Unannotated protein. (265 aa)
modFUnannotated protein. (490 aa)
modCUnannotated protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa)
dnaC_3Unannotated protein. (248 aa)
ybhF_2Unannotated protein. (578 aa)
glnQUnannotated protein. (240 aa)
yheS_1Unannotated protein. (531 aa)
BZ172_20435Unannotated protein; Belongs to the ABC transporter superfamily. (623 aa)
potGUnannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
artP-2Unannotated protein. (242 aa)
ybjZUnannotated protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)
clpAUnannotated protein; Belongs to the ClpA/ClpB family. (758 aa)
cudCUnannotated protein. (573 aa)
cydDUnannotated protein. (588 aa)
rarAUnannotated protein. (447 aa)
msbAUnannotated protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
ssuBUnannotated protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system. (255 aa)
BZ172_21305Unannotated protein. (635 aa)
GCA_000283715_01097Unannotated protein. (265 aa)
GCA_000283715_01111Unannotated protein. (251 aa)
lolD_1Unannotated protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (233 aa)
potA_1Unannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
yecCUnannotated protein. (250 aa)
GCA_000283715_01259Unannotated protein. (251 aa)
araGUnannotated protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa)
GCA_000283715_01317Unannotated protein. (265 aa)
ruvBUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
znuCUnannotated protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa)
GCA_000283715_01456Unannotated protein. (265 aa)
btuDUnannotated protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
sufCUnannotated protein. (248 aa)
GCA_000283715_01688Unannotated protein. (1225 aa)
GCA_000283715_01740Unannotated protein. (260 aa)
GCA_000283715_01759Unannotated protein. (364 aa)
BZ172_25170Unannotated protein. (265 aa)
BZ172_26045Unannotated protein. (561 aa)
gsiA_4Unannotated protein; Belongs to the ABC transporter superfamily. (328 aa)
GCA_000283715_01883Unannotated protein. (251 aa)
potA_2Unannotated protein; Belongs to the ABC transporter superfamily. (337 aa)
hrpAUnannotated protein. (1300 aa)
sitB_2Unannotated protein. (275 aa)
BZ172_25330Unannotated protein. (248 aa)
tyrRUnannotated protein. (513 aa)
ugpC_2Unannotated protein. (248 aa)
pspFUnannotated protein. (325 aa)
sapDUnannotated protein; Belongs to the ABC transporter superfamily. (330 aa)
sapFUnannotated protein. (268 aa)
oppFUnannotated protein; Belongs to the ABC transporter superfamily. (334 aa)
oppDUnannotated protein; Belongs to the ABC transporter superfamily. (337 aa)
fliIUnannotated protein. (457 aa)
proV_1Unannotated protein. (308 aa)
mglAUnannotated protein. (506 aa)
gsiA_1Unannotated protein; Belongs to the ABC transporter superfamily. (529 aa)
BZ172_01310Unannotated protein. (265 aa)
ccmAUnannotated protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa)
yojIUnannotated protein. (547 aa)
zraR_2Unannotated protein. (461 aa)
hisPUnannotated protein. (257 aa)
GCA_000283715_02762Unannotated protein. (265 aa)
cysAUnannotated protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
fhlA_1Unannotated protein. (670 aa)
yphEUnannotated protein. (503 aa)
qseF_1Unannotated protein. (444 aa)
GCA_000283715_03055Unannotated protein. (251 aa)
GCA_000283715_03074Unannotated protein. (265 aa)
clpBUnannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa)
GCA_000283715_03160Unannotated protein. (265 aa)
proV_2Unannotated protein. (400 aa)
recAUnannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa)
ygaAUnannotated protein; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. (504 aa)
GCA_000283715_03279Unannotated protein. (387 aa)
recDUnannotated protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...] (608 aa)
BZ172_05995Unannotated protein. (592 aa)
ecfA1_2Unannotated protein. (225 aa)
ecfA1_1Unannotated protein. (225 aa)
yggR_3Unannotated protein. (326 aa)
GCA_000283715_03745Unannotated protein. (265 aa)
hflBUnannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (647 aa)
mlaFUnannotated protein. (269 aa)
lptBUnannotated protein. (241 aa)
artM_2Unannotated protein. (252 aa)
GCA_000283715_03896Unannotated protein. (265 aa)
yheS_2Unannotated protein. (637 aa)
ugpC_1Unannotated protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
livFUnannotated protein; Belongs to the ABC transporter superfamily. (237 aa)
livGUnannotated protein. (255 aa)
ftsEUnannotated protein; Part of the ABC transporter FtsEX involved in cellular division. (222 aa)
nikDUnannotated protein; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa)
nikEUnannotated protein; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa)
ybhF_1Unannotated protein. (911 aa)
GCA_000283715_04080Unannotated protein. (265 aa)
dnaAUnannotated protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (467 aa)
GCA_000283715_04195Unannotated protein. (265 aa)
dppDUnannotated protein; Belongs to the ABC transporter superfamily. (327 aa)
dppFUnannotated protein; Belongs to the ABC transporter superfamily. (334 aa)
atpDUnannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa)
ravAUnannotated protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa)
pstBUnannotated protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)
rbsAUnannotated protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
GCA_000283715_04399Unannotated protein. (265 aa)
rhoUnannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
glnGUnannotated protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
hslUUnannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
GCA_000283715_04633Unannotated protein. (265 aa)
zraR_1Unannotated protein. (441 aa)
malKUnannotated protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (371 aa)
dnaB_1Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa)
phnLUnannotated protein. (226 aa)
phnKUnannotated protein. (252 aa)
phnCUnannotated protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (262 aa)
ytfRUnannotated protein. (500 aa)
GCA_000283715_04996Unannotated protein. (265 aa)
fecEUnannotated protein. (255 aa)
dnaC_1Unannotated protein. (245 aa)
radAUnannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa)
yjjKUnannotated protein. (555 aa)
GCA_000283715_05159Unannotated protein. (265 aa)
spaLUnannotated protein; Required for surface presentation of invasion plasmid antigens. Probable catalytic subunit of a protein translocase. Required for invasion and for secretion of the three IPA proteins (By similarity). (430 aa)
GCA_000283715_05253Unannotated protein. (251 aa)
GCA_000283715_05265Unannotated protein. (265 aa)
GCA_000283715_05291Unannotated protein. (265 aa)
BZ172_30355Unannotated protein. (949 aa)
BZ172_02585Unannotated protein. (265 aa)
thiQUnannotated protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa)
gspE_3Unannotated protein. (461 aa)
drrAUnannotated protein. (308 aa)
fhuCUnannotated protein. (265 aa)
metN_2Unannotated protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
GCA_000283715_00245Unannotated protein. (929 aa)
BZ172_19440Unannotated protein. (251 aa)
tauBUnannotated protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa)
lonUnannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifical [...] (784 aa)
mdlAUnannotated protein. (590 aa)
mdlBUnannotated protein. (593 aa)
dnaXUnannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (641 aa)
ybbLUnannotated protein. (225 aa)
Your Current Organism:
Shigella sonnei
NCBI taxonomy Id: 216599
Other names: S. sonnei 53G, Shigella sonnei 53G, Shigella sonnei str. 53G
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