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| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (300 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (280 aa) |
| | BPSY_0014 | Acetolactate synthase small subunit. (184 aa) |
| | BPSY_0015 | Acetolactate synthase large subunit. (644 aa) |
| | BPSY_0019 | Hypothetical protein. (256 aa) |
| | BPSY_0032 | GNAT family acetyltransferase. (163 aa) |
| | BPSY_0041 | Mannose-1-phosphate guanylyltransferase. (374 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (564 aa) |
| | BPSY_0051 | Aldo/keto reductase family oxidoreductase. (282 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (134 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (348 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa) |
| | BPSY_0101 | 1-acyl-sn-glycerol-3-phosphate acyltransferase. (295 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (226 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (522 aa) |
| | BPSY_0136 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (296 aa) |
| | BPSY_0141 | dTDP-4-dehydrorhamnose 3,5-epimerase/dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (482 aa) |
| | BPSY_0142 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (339 aa) |
| | BPSY_0153 | Aminotransferase. (416 aa) |
| | BPSY_0159 | N-acetyltransferase GCN5. (152 aa) |
| | BPSY_0166 | Hypothetical protein. (168 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (529 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (263 aa) |
| | BPSY_0197 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (489 aa) |
| | BPSY_0213 | Alpha-xylosidase; Belongs to the glycosyl hydrolase 31 family. (675 aa) |
| | BPSY_0214 | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (708 aa) |
| | BPSY_0230 | Putative transglycosylase. (356 aa) |
| | BPSY_0250 | Type II restriction enzyme recognizing CTGCAG. (316 aa) |
| | BPSY_0259 | ArsR family transcriptional regulator. (119 aa) |
| | BPSY_0266 | Transcriptional regulator, HipB-like protein. (138 aa) |
| | BPSY_0306 | Transposase, IS3 family. (145 aa) |
| | BPSY_0309 | Hypothetical protein. (216 aa) |
| | BPSY_0310 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase. (299 aa) |
| | BPSY_0340 | Maltose O-acetyltransferase. (200 aa) |
| | BPSY_0342 | Galactoside O-acetyltransferase. (219 aa) |
| | BPSY_0353 | Bacterial regulatory protein, arsR family. (127 aa) |
| | BPSY_0356 | Transcriptional regulator, ArsR family. (97 aa) |
| | BPSY_0374 | NmrA-like protein. (312 aa) |
| | BPSY_0380 | Beta-glucosidase. (726 aa) |
| | BPSY_0394 | ROK family protein. (371 aa) |
| | BPSY_0423 | NAD-dependent epimerase/dehydratase. (217 aa) |
| | BPSY_0446 | Glycosyl hydrolase, family 32; Belongs to the glycosyl hydrolase 32 family. (509 aa) |
| | BPSY_0451 | ADP-ribosylglycohydrolase. (334 aa) |
| | BPSY_0455 | Glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family. (409 aa) |
| | BPSY_0456 | Glycosyl hydrolase family 3; Belongs to the glycosyl hydrolase 3 family. (751 aa) |
| | grpE | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] (239 aa) |
| | BPSY_0483 | Alpha-1,4-glucosidase. (562 aa) |
| | BPSY_0494 | Threonine dehydratase. (421 aa) |
| | BPSY_0500 | Oligo-1,6-glucosidase. (618 aa) |
| | BPSY_0506 | Trehalose 6-phosphate synthase/phosphatase. (809 aa) |
| | BPSY_0509 | Alpha-1,4-glucosidase. (591 aa) |
| | BPSY_0517 | ROK family protein. (428 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (336 aa) |
| | BPSY_0540 | Aminotransferase class I and II. (439 aa) |
| | BPSY_0573 | Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (471 aa) |
| | BPSY_0579 | NmrA-like family protein. (283 aa) |
| | BPSY_0583 | Asparaginase. (338 aa) |
| | BPSY_0602 | Glycosyl hydrolase; Belongs to the glycosyl hydrolase 3 family. (717 aa) |
| | BPSY_0604 | CBS domain protein. (442 aa) |
| | BPSY_0615 | Flavodoxin-like protein. (196 aa) |
| | BPSY_0625 | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (818 aa) |
| | BPSY_0649 | Alpha-1,4-glucosidase. (599 aa) |
| | BPSY_0662 | Ribulose bisphosphate carboxylase large chain, catalytic domain. (372 aa) |
| | htpX | Peptidase family M48; Belongs to the peptidase M48B family. (312 aa) |
| | BPSY_0672 | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (970 aa) |
| | BPSY_0673 | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (813 aa) |
| | BPSY_0679 | Hydroxyneurosporene synthase CrtC. (362 aa) |
| | BPSY_0684 | Polysaccharide deacetylase. (429 aa) |
| | BPSY_0692 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (352 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (350 aa) |
| | BPSY_0711 | High-affinity Fe2 /Pb2 permease. (586 aa) |
| | BPSY_0722 | Aldo/keto diketogulonate reductase. (284 aa) |
| | BPSY_0726 | Carboxy-cis,cis-muconate cyclase. (403 aa) |
| | BPSY_0740 | Mevalonate kinase. (366 aa) |
| | BPSY_0741 | Diphosphomevalonate decarboxylase. (344 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (738 aa) |
| | BPSY_0753 | Ornithine carbamoyltransferase. (274 aa) |
| | BPSY_0759 | PE-PGRS family protein. (450 aa) |
| | BPSY_0827 | Aspartate kinase; Belongs to the aspartokinase family. (254 aa) |
| | BPSY_0828 | Aspartate kinase. (190 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (356 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (635 aa) |
| | BPSY_0833 | Myo-inositol-1-phosphate synthase. (380 aa) |
| | BPSY_0844 | glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (319 aa) |
| | BPSY_0860 | Amine oxidase. (529 aa) |
| | BPSY_0862 | Chorismate mutase TyrA. (143 aa) |
| | BPSY_0877 | Glycosyl hydrolases family 31, Alpha-glucosidase or alpha-xylosidase; Belongs to the glycosyl hydrolase 31 family. (821 aa) |
| | BPSY_0881 | ROK family transcriptional regulator. (405 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (352 aa) |
| | BPSY_0907 | Glycoside hydrolase family 3. (773 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (521 aa) |
| | BPSY_0916 | Homoserine dehydrogenase. (437 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (366 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa) |
| | BPSY_0928 | Aspartate aminotransferase. (406 aa) |
| | BPSY_0939 | acetyl-CoA carboxylase alpha chain. (643 aa) |
| | BPSY_0940 | propionyl-CoA carboxylase beta chain. (549 aa) |
| | ispD | 4-diphosphocytidyl-2-methyl-D-erithritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (276 aa) |
| | BPSY_0971 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (378 aa) |
| | BPSY_0972 | 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (396 aa) |
| | BPSY_0988 | ATPase associated with various cellular activities AAA_3. (330 aa) |
| | hisC | Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa) |
| | BPSY_1001 | N-succinyldiaminopimelate aminotransferase. (381 aa) |
| | BPSY_1006 | Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa) |
| | BPSY_1009 | 4-alpha-glucanotransferase. (743 aa) |
| | BPSY_1012 | Aldehyde-alcohol dehydrogenase 2; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (915 aa) |
| | adk | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (185 aa) |
| | BPSY_1058 | ROK family protein. (409 aa) |
| | BPSY_1064 | Riboflavin kinase. (404 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | BPSY_1070 | Phosphoglucomutase, alpha-D-glucose phosphate-specific. (575 aa) |
| | BPSY_1071 | Diacylglycerol kinase catalytic domain protein. (367 aa) |
| | BPSY_1073 | Phosphotransferase enzyme family protein. (379 aa) |
| | BPSY_1076 | GntR family transcriptional regulator. (279 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (318 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | BPSY_1092 | Mannose-6-phosphate isomerase. (481 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (397 aa) |
| | BPSY_1096 | Putative universal stress protein. (356 aa) |
| | BPSY_1112 | 6-phosphogluconate dehydrogenase-like protein. (291 aa) |
| | BPSY_1114 | Putative gluconokinase. (181 aa) |
| | BPSY_1119 | Glycosyl hydrolase family 32. (1270 aa) |
| | BPSY_1145 | Phosphotransferase enzyme family. (384 aa) |
| | BPSY_1148 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. (414 aa) |
| | BPSY_1152 | Putative membrane protein. (501 aa) |
| | tilS | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (365 aa) |
| | BPSY_1158 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (190 aa) |
| | BPSY_1168 | acyl-CoA thioesterase 1. (433 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (531 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (247 aa) |
| | BPSY_1182 | Citrate synthase I; Belongs to the citrate synthase family. (429 aa) |
| | BPSY_1207 | Cystathionine beta-synthase. (337 aa) |
| | BPSY_1208 | Cystathionine gamma-synthase. (391 aa) |
| | BPSY_1235 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (636 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (395 aa) |
| | BPSY_1240 | Esterase. (453 aa) |
| | BPSY_1251 | Putative glycosidase. (523 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (346 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa) |
| | BPSY_1270 | Purl. (1240 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (257 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (430 aa) |
| | BPSY_1274 | Threonine aldolase. (341 aa) |
| | BPSY_1275 | Alpha amylase. (455 aa) |
| | BPSY_1278 | NAD-dependent epimerase/dehydratase. (211 aa) |
| | BPSY_1284 | 3-ketoacyl-(acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | BPSY_1289 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (336 aa) |
| | BPSY_1290 | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (359 aa) |
| | BPSY_1299 | ArsR family transcriptional regulator. (241 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (617 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa) |
| | BPSY_1322 | Phosphoserine phosphatase. (213 aa) |
| | BPSY_1326 | Inositol monophosphatase. (275 aa) |
| | BPSY_1331 | Adenylosuccinate lyase. (486 aa) |
| | BPSY_1339 | MoxR family protein. (357 aa) |
| | BPSY_1350 | UspA domain-containing protein. (336 aa) |
| | BPSY_1353 | Methyltransferase. (289 aa) |
| | BPSY_1360 | Polyphosphate glucokinase. (253 aa) |
| | BPSY_1361 | Aminotransferase. (441 aa) |
| | BPSY_1368 | NADH(P)-binding protein, PF13460 family. (228 aa) |
| | BPSY_1378 | Dihydrolipoamide dehydrogenase. (493 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (363 aa) |
| | argJ | Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (389 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (318 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (429 aa) |
| | BPSY_1394 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (324 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (412 aa) |
| | argH | Argininosuccinate lyase. (492 aa) |
| | BPSY_1399 | Oxidoreductase family, NAD-binding Rossmann fold domain protein. (372 aa) |
| | BPSY_1435 | Threonine synthase. (499 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (440 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (448 aa) |
| | prs | Ribose-phosphate pyrophosphokinase PrsA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (337 aa) |
| | BPSY_1444 | Phosphoglycerate mutase. (240 aa) |
| | BPSY_1461 | Phenazine biosynthesis protein PhzF family. (281 aa) |
| | BPSY_1471 | Phosphoglycerate dehydrogenase-related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa) |
| | BPSY_1487 | ArsR family transcriptional regulator. (258 aa) |
| | BPSY_1490 | Uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (341 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | BPSY_1498 | Permease. (203 aa) |
| | BPSY_1502 | Aldo/keto reductase. (288 aa) |
| | BPSY_1520 | Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa) |
| | BPSY_1521 | GMP reductase. (381 aa) |
| | BPSY_1529 | CDP-diglyceride synthetase. (330 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (137 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (521 aa) |
| | trpB | Bifunctional tryptophan synthase subunit beta/indole-3-glycerol phosphate synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. (698 aa) |
| | BPSY_1537 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (87 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | BPSY_1546 | Putative hydrolase or phosphatase. (239 aa) |
| | BPSY_1551 | UTP--glucose-1-phosphate uridylyltransferase. (506 aa) |
| | BPSY_1556 | Methionine synthase II. (455 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (540 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (306 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (405 aa) |
| | BPSY_1576 | Class III aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa) |
| | BPSY_1579 | Glycosyl hydrolase family protein. (685 aa) |
| | BPSY_1586 | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (780 aa) |
| | BPSY_1593 | PAC2 family protein. (288 aa) |
| | BPSY_1595 | Fructosamine kinase. (263 aa) |
| | BPSY_1598 | Transketolase; Belongs to the transketolase family. (701 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (369 aa) |
| | BPSY_1600 | Haloacid dehalogenase domain-containing protein hydrolase, type 3. (281 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (264 aa) |
| | pgk | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | BPSY_1606 | Shikimate 5-dehydrogenase. (309 aa) |
| | gpmA-2 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (269 aa) |
| | BPSY_1626 | Nagc-type transcriptional regulator. (390 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (770 aa) |
| | BPSY_1638 | Glutamate synthase small chain GltD. (510 aa) |
| | BPSY_1639 | Glutamate synthase. (1523 aa) |
| | BPSY_1640 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (407 aa) |
| | BPSY_1647 | Branched-chain-amino-acid transaminase. (375 aa) |
| | BPSY_1654 | Hypothetical protein; Putative CBS domain pair. (465 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (414 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | aroK | Bifunctional shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (548 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (397 aa) |
| | BPSY_1678 | Phosphoglycerate mutase family protein. (210 aa) |
| | BPSY_1686 | Histidinol-phosphate phosphatase. (281 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (450 aa) |
| | BPSY_1695 | Glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (706 aa) |
| | BPSY_1700 | Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (166 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (750 aa) |
| | BPSY_1717 | Phosphomannomutase. (278 aa) |
| | eno-2 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | BPSY_1740 | Phosphinothricin N-acetyltransferase. (189 aa) |
| | BPSY_1744 | NAD(P)H oxidoreductase. (203 aa) |
| | BPSY_1751 | Aminotransferase. (419 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | BPSY_1768 | Succinate dehydrogenase flavoprotein subunit. (653 aa) |
| | BPSY_1769 | Succinate dehydrogenase/fumarate reductase. (339 aa) |
| | BPSY_1770 | Methyltransferase. (223 aa) |
| | BPSY_1772 | Aspartate aminotransferase. (392 aa) |
| | tig | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (459 aa) |
| | BPSY_1791 | Hydrolase. (271 aa) |
| | BPSY_1796 | NAD-dependent oxidoreductase. (346 aa) |
| | BPSY_1815 | Alpha-1,4-glucosidase. (616 aa) |
| | BPSY_1834 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (409 aa) |
| | BPSY_1836 | Acyltransferase family protein. (236 aa) |
| | trpD | Anthranilate phosphoribosyltransferase 1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (353 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (347 aa) |
| | BPSY_1856 | 2,5-didehydrogluconate reductase. (292 aa) |
| | BPSY_1858 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa) |
| | BPSY_1873 | Prephenate dehydrogenase. (367 aa) |
| | BPSY_1874 | Prephenate dehydratase. (341 aa) |
| | BPSY_1891 | ArsC family protein; Belongs to the ArsC family. (149 aa) |
| | BPSY_1892 | Glyceraldehyde 3-phosphate dehydrogenase domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (350 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (359 aa) |
| | BPSY_1895 | Aldose 1-epimerase. (329 aa) |
| | BPSY_1910 | Transcriptional regulator/sugar kinase. (334 aa) |
| | BPSY_1912 | ROK family protein. (384 aa) |
| | BPSY_1916 | ROK family transcriptional regulator. (408 aa) |
| | BPSY_1917 | Fructokinase. (300 aa) |
| | BPSY_1948 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (398 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (320 aa) |
| | BPSY_1955 | 16S RNA methylase. (265 aa) |
| | hisA | Phosphoribosyl isomerase A. (241 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Histidine biosynthesis bifunctional protein HisB (histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase). (199 aa) |
| | hisC-2 | Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (385 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (460 aa) |
| | BPSY_1978 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (263 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (437 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (420 aa) |
| | BPSY_2006 | Phenazine biosynthesis protein PhzF family protein. (277 aa) |
| | BPSY_2020 | Acyl-coenzyme A thioesterase AcoT. (450 aa) |
| | BPSY_2034 | Vitamin K epoxide reductase. (220 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (315 aa) |
| | BPSY_2041 | Cystathionine beta-lyase. (395 aa) |
| | BPSY_2047 | Uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (356 aa) |
| | proC-2 | NADP oxidoreductase, coenzyme F420-dependent; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa) |
| | proC-3 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | BPSY_2068 | Galactoside O-acetyltransferase. (209 aa) |
| | BPSY_2078 | ArsR family transcriptional regulator. (176 aa) |
| | BPSY_2085 | GntR family transcriptional regulator. (431 aa) |
| | BPSY_2086 | FAD/FMN-containing dehydrogenase. (659 aa) |
| | BPSY_2087 | Hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family. (347 aa) |
| | BPSY_2102 | Alcohol dehydrogenase. (347 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (248 aa) |
| | BPSY_2133 | ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa) |
| | BPSY_2206 | Bacterial regulatory protein, arsR family. (122 aa) |
