STRINGSTRING
ubiE ubiE ubiD ubiD visC visC visB visB ubiC ubiC ubiA ubiA ECA1070 ECA1070 ECA1071 ECA1071 bolA bolA ubiG ubiG ubiF ubiF ECA1927 ECA1927 ubiX ubiX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
ubiD3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (498 aa)
visCPutative monooxygenase; Similar to Escherichia coli protein VisC or b2906 SWALL:VISC_ECOLI (SWALL:P25535) (400 aa) fasta scores: E(): 3.8e-114, 72.43% id in 399 aa. (403 aa)
visBSimilar to Escherichia coli 2-octaprenyl-6-methoxyphenol hydroxylase UbiH or VisB or b2907 SWALL:UBIH_ECOLI (SWALL:P25534) (392 aa) fasta scores: E(): 2.4e-96, 62.24% id in 392 aa. (392 aa)
ubiCChorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. (177 aa)
ubiA4-hydroxybenzoate octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (287 aa)
ECA1070Putative 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. (474 aa)
ECA1071Conserved hypothetical protein; Similar to Escherichia coli O157:H7 orf, hypothetical protein z4045 or ecs3591 SWALL:Q8X7Z8 (EMBL:AE005501) (78 aa) fasta scores: E(): 7.7e-25, 81.33% id in 75 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm2923 or sty3048 SWALL:Q8XEM2 (EMBL:AE008833) (78 aa) fasta scores: E(): 2.1e-24, 78.66% id in 75 aa. (75 aa)
bolAMorphogene, putative regulator of murein genes; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri BolA or b0435 or c0548 or sf0379 SWALL:BOLA_ECOLI (SWALL:P15298) (105 aa) fasta scores: E(): 4.6e-28, 71.28% id in 101 aa, and to Salmonella typhimurium, and Salmonella typhi morphogene, putative regulator of murein genes bola or stm0446 or sty0488 SWALL:Q8XFC2 (EMBL:AE008716) (105 aa) fasta scores: E(): 5.4e-28, 70.29% id in 101 aa; Belongs to the BolA/IbaG family. (104 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (241 aa)
ubiFSimilar to Escherichia coli 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF or b0662 SWALL:UBIF_ECOLI (SWALL:P75728) (391 aa) fasta scores: E(): 4.8e-94, 65.7% id in 382 aa. (388 aa)
ECA1927Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein ydhd or b1654 or c2048 or z2676 or ecs2363 or sf1682 SWALL:YDHD_ECOLI (SWALL:P37010) (115 aa) fasta scores: E(): 5e-40, 88.79% id in 116 aa, and to Salmonella typhimurium, and Salmonella typhi putative glutaredoxin protein ydhd or stm1433 or sty1689 SWALL:Q8XGR7 (EMBL:AE008762) (115 aa) fasta scores: E(): 1.5e-40, 90.51% id in 116 aa; Belongs to the glutaredoxin family. Monothiol subfamily. (116 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (190 aa)
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.