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outM outM ECA1096 ECA1096 ECA0789 ECA0789 secG secG pilN pilN secE secE hofQ hofQ hofC hofC ppdD ppdD ECA3595 ECA3595 ECA3269 ECA3269 outC outC outD outD outE outE outF outF outG outG outH outH outI outI outJ outJ outK outK outL outL hasE hasE outN outN prtD prtD prtE prtE dspF dspF hrcC hrcC hrcN hrcN hrpE hrpE hrcJ hrcJ hrpB hrpB hrpJ hrpJ hrpI hrpI hrcQ hrcQ hrcR hrcR hrcS hrcS hrcU hrcU fliI fliI fliP fliP fliQ fliQ flhA flhA flhB flhB virB6 virB6 hasD hasD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
outMGeneral secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (164 aa)
ECA1096Similar to Pseudomonas putida protein secretion ABC efflux system, membrane fusion protein pp0803 SWALL:AAN66428 (EMBL:AE016777) (394 aa) fasta scores: E(): 9.1e-67, 54.23% id in 378 aa, and to Escherichia coli O157:H7 putative membrane spanning export protein z0635 or ecs0544 SWALL:Q8XD11 (EMBL:AE005229) (391 aa) fasta scores: E(): 2.9e-66, 54.3% id in 372 aa. (389 aa)
ECA0789Putative membrane protein; Similar to Actinobacillus actinomycetemcomitans rough colony protein A RcpA SWALL:Q9X6J1 (EMBL:AF139249) (460 aa) fasta scores: E(): 2.1e-15, 29.2% id in 404 aa, and to Escherichia coli protein transport protein HofQ precursor SWALL:HOFQ_ECOLI (SWALL:P34749) (412 aa) fasta scores: E(): 2.9e-10, 24.71% id in 433 aa, and to Salmonella typhi type II secretion system protein HofQ SWALL:Q8Z206 (EMBL:AL627281) (412 aa) fasta scores: E(): 7e-10, 27.27% id in 253 aa; Belongs to the bacterial secretin family. (478 aa)
secGProtein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (110 aa)
pilNPutative Type IV pilus protein; Similar to Escherichia coli, and Salmonella typhimurium lipoprotein PilN SWALL:O07372 (EMBL:AB021078) (560 aa) fasta scores: E(): 8.1e-61, 40.71% id in 560 aa. (554 aa)
secEPreprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa)
hofQPutative type II secretion system protein; Similar to Escherichia coli protein transport protein HofQ precursor HofQ or HopQ or b3391 SWALL:HOFQ_ECOLI (SWALL:P34749) (412 aa) fasta scores: E(): 3.1e-71, 52.3% id in 390 aa, and to Yersinia pestis putative membrane transport protein ypo0150 or hofq or y3932 SWALL:Q8ZJF8 (EMBL:AJ414141) (374 aa) fasta scores: E(): 3.9e-84, 62.89% id in 380 aa. (393 aa)
hofCSimilar to Escherichia coli protein transport protein HofC or HopC or b0106 SWALL:HOFC_ECOLI (SWALL:P36646) (400 aa) fasta scores: E(): 5.6e-55, 40.15% id in 401 aa. (401 aa)
ppdDSimilar to Escherichia coli prepilin peptidase dependent protein D precursor PpdD or b0108 SWALL:PPDD_ECOLI (SWALL:P36647) (146 aa) fasta scores: E(): 2.8e-32, 60.69% id in 145 aa. (148 aa)
ECA3595Putative membrane protein; Similar to Yersinia pestis putative exported protein ypo3523 or y0661 SWALL:Q8ZB96 (EMBL:AJ414157) (1305 aa) fasta scores: E(): 0, 65.19% id in 1313 aa, and to Salmonella typhi putative exported protein ytfn or sty4769 SWALL:Q8Z149 (EMBL:AL627283) (1259 aa) fasta scores: E(): 0, 57.79% id in 1315 aa. (1345 aa)
ECA3269HlyD family secretion protein; Similar to Rhizobium leguminosarum PrsE protein prsE SWALL:O05694 (EMBL:Y12758) (435 aa) fasta scores: E(): 4.6e-27, 29.72% id in 434 aa, and to Pseudomonas putida HlyD family secretion protein pp0166 SWALL:AAN65799 (EMBL:AE016774) (458 aa) fasta scores: E(): 1.9e-103, 65.19% id in 454 aa. (453 aa)
outCSimilar to Erwinia carotovora general secretion pathway protein C OutC SWALL:GSPC_ERWCA (SWALL:P31699) (285 aa) fasta scores: E(): 6.4e-96, 91.63% id in 287 aa, and to Erwinia chrysanthemi general secretion pathway protein C OutC SWALL:GSQC_ERWCH (SWALL:Q01564) (272 aa) fasta scores: E(): 1.5e-49, 52.01% id in 273 aa. (287 aa)
outDSimilar to Erwinia carotovora general secretion pathway protein D precursor OutD SWALL:GSPD_ERWCA (SWALL:P31701) (650 aa) fasta scores: E(): 3e-215, 92.76% id in 650 aa, and to Klebsiella pneumoniae general secretion pathway protein D precursor PulD SWALL:GSPD_KLEPN (SWALL:P15644) (660 aa) fasta scores: E(): 1.9e-173, 74.31% id in 654 aa. (650 aa)
outEGeneral secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (498 aa)
outFSimilar to Erwinia carotovora general secretion pathway protein F OutF SWALL:GSPF_ERWCA (SWALL:P31705) (408 aa) fasta scores: E(): 7.6e-150, 96.56% id in 408 aa, and to Erwinia chrysanthemi general secretion pathway protein F OutF SWALL:GSPF_ERWCH (SWALL:P31704) (404 aa) fasta scores: E(): 1.2e-116, 77.39% id in 407 aa. (408 aa)
outGSimilar to Erwinia carotovora general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCA (SWALL:P31586) (156 aa) fasta scores: E(): 2.3e-51, 97.88% id in 142 aa, and to Erwinia chrysanthemi general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCH (SWALL:P31585) (153 aa) fasta scores: E(): 1.9e-42, 85.07% id in 134 aa. (146 aa)
outHSimilar to Erwinia carotovora general secretion pathway protein H precursor OutH SWALL:GSPH_ERWCA (SWALL:P31587) (188 aa) fasta scores: E(): 1.7e-68, 92.02% id in 188 aa, and to Erwinia chrysanthemi general secretion pathway protein H precursor OutH SWALL:GSPH_ERWCH (SWALL:P24687) (181 aa) fasta scores: E(): 7.3e-32, 52.24% id in 178 aa. (188 aa)
outISimilar to Erwinia carotovora general secretion pathway protein I precursor OutI SWALL:GSPI_ERWCA (SWALL:P31588) (121 aa) fasta scores: E(): 1.4e-44, 94.21% id in 121 aa, and to Erwinia chrysanthemi general secretion pathway protein I precursor OutI SWALL:GSPI_ERWCH (SWALL:P24688) (125 aa) fasta scores: E(): 3.3e-27, 59.32% id in 118 aa. (121 aa)
outJSimilar to Erwinia carotovora general secretion pathway protein J precursor OutJ SWALL:GSPJ_ERWCA (SWALL:P31589) (216 aa) fasta scores: E(): 1e-74, 95.96% id in 198 aa, and to Erwinia chrysanthemi general secretion pathway protein J precursor OutJ SWALL:GSPJ_ERWCH (SWALL:P24689) (206 aa) fasta scores: E(): 3.8e-43, 60.82% id in 194 aa. (216 aa)
outKSimilar to Erwinia carotovora general secretion pathway protein K OutK SWALL:GSPK_ERWCA (SWALL:P31706) (328 aa) fasta scores: E(): 5.7e-125, 95.12% id in 328 aa, and to Erwinia chrysanthemi general secretion pathway protein K OutK SWALL:GSPK_ERWCH (SWALL:P24690) (354 aa) fasta scores: E(): 8.7e-44, 50.69% id in 359 aa. (328 aa)
outLGeneral secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (425 aa)
hasEHlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap). (452 aa)
outNSimilar to Erwinia carotovora general secretion pathway protein N OutN SWALL:GSPN_ERWCA (SWALL:P31710) (248 aa) fasta scores: E(): 3e-88, 88.71% id in 248 aa, and to Klebsiella pneumoniae general secretion pathway protein N PulN SWALL:GSPN_KLEPN (SWALL:P15753) (252 aa) fasta scores: E(): 2.5e-26, 35.88% id in 248 aa. (248 aa)
prtDSimilar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap. (575 aa)
prtESimilar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap. (442 aa)
dspFPutative avirulence protein; Similar to Erwinia amylovora DspF or DspB SWALL:O54621 (EMBL:U97504) (139 aa) fasta scores: E(): 1.8e-19, 42.85% id in 133 aa, and to Pseudomonas syringae avirulence protein AvrF SWALL:O66102 (EMBL:U97505) (129 aa) fasta scores: E(): 1.1e-13, 36.64% id in 131 aa. (140 aa)
hrcCType III secretion protein; Similar to Pectobacterium carotovorum subsp. carotovorum HrcC SWALL:Q93FZ1 (EMBL:AF302656) (689 aa) fasta scores: E(): 0, 95.78% id in 688 aa, and to Erwinia amylovora HrcC precursor SWALL:Q46625 (EMBL:U56662) (676 aa) fasta scores: E(): 1.3e-169, 68.65% id in 654 aa. (689 aa)
hrcNType III secretion protein; Similar to Erwinia amylovora HrcN SWALL:Q46642 (EMBL:L25828) (454 aa) fasta scores: E(): 3.9e-124, 78.7% id in 446 aa, and to Pantoea agglomerans HrcN protein HrcN SWALL:Q937I3 (EMBL:X99768) (454 aa) fasta scores: E(): 4.7e-121, 76.4% id in 445 aa. (456 aa)
hrpEType III secretion protein; Similar to Pectobacterium carotovorum subsp. carotovorum HrpE SWALL:Q93FZ4 (EMBL:AF302656) (199 aa) fasta scores: E(): 3.5e-65, 87.37% id in 198 aa, and to Erwinia chrysanthemi HrpE SWALL:Q8KUL7 (EMBL:AF448202) (200 aa) fasta scores: E(): 7.5e-28, 42.85% id in 196 aa. (200 aa)
hrcJType III secretion protein; Similar to Pectobacterium carotovorum subsp. carotovorum HrcJ SWALL:Q93FZ6 (EMBL:AF302656) (255 aa) fasta scores: E(): 2.1e-90, 95.66% id in 254 aa, and to Erwinia chrysanthemi HrcJ SWALL:Q8KUL9 (EMBL:AF448202) (245 aa) fasta scores: E(): 5.5e-67, 75.94% id in 237 aa. (255 aa)
hrpBType III secretion protein; Similar to Pectobacterium carotovorum subsp. carotovorum HrpB SWALL:Q93FZ7 (EMBL:AF302656) (144 aa) fasta scores: E(): 1.3e-49, 95.1% id in 143 aa, and to Erwinia chrysanthemi HrpB SWALL:Q8KUM0 (EMBL:AF448202) (122 aa) fasta scores: E(): 1.9e-18, 62.03% id in 108 aa. (145 aa)
hrpJType III secretion protein; Similar to Pectobacterium carotovorum subsp. atrosepticum secretion protein HrpJ type III HrpJ SWALL:Q8KM25 (EMBL:AJ496800) (402 aa) fasta scores: E(): 1.2e-121, 90.79% id in 402 aa, and to Erwinia chrysanthemi HrpJ WALL:AAO34609 (EMBL:AY169276) (393 aa) fasta scores: E(): 2.3e-80, 64.59% id in 387 aa. (396 aa)
hrpIType III secretion protein; Similar to Erwinia amylovora harpin secretion protein HrpI SWALL:HRPI_ERWAM (SWALL:P35654) (697 aa) fasta scores: E(): 2e-193, 76.35% id in 702 aa, and to Pantoea agglomerans HrcV protein HrcV SWALL:Q937I5 (EMBL:X99768) (719 aa) fasta scores: E(): 2.2e-196, 75.42% id in 704 aa. (700 aa)
hrcQType III secretion protein; Similar to Erwinia amylovora HrcQ SWALL:Q46645 (EMBL:L25828) (338 aa) fasta scores: E(): 1.8e-11, 34.59% id in 370 aa, and to Pantoea agglomerans HrcQb protein SWALL:Q47855 (EMBL:X99768) (108 aa) fasta scores: E(): 9.8e-11, 46.22% id in 106 aa. (405 aa)
hrcRType III secretion protein; Similar to Erwinia herbicola harpin secretion protein HrcR SWALL:HRCR_ERWHE (SWALL:Q47856) (217 aa) fasta scores: E(): 6.3e-63, 74.19% id in 217 aa, and to Erwinia amylovora harpin secretion protein HrcR SWALL:HRCR_ERWAM (SWALL:Q46646) (217 aa) fasta scores: E(): 1.8e-62, 75.57% id in 217 aa. (217 aa)
hrcSType III secretion protein; Similar to Erwinia amylovora HrcS SWALL:Q46647 (EMBL:L25828) (86 aa) fasta scores: E(): 2.8e-22, 76.19% id in 84 aa, and to Pantoea agglomerans HrcS protein HrcS SWALL:Q47857 (EMBL:X99768) (83 aa) fasta scores: E(): 2.6e-21, 75.61% id in 82 aa. (86 aa)
hrcUType III secretion protein; Similar to Erwinia amylovora HrcU SWALL:Q46649 (EMBL:L25828) (360 aa) fasta scores: E(): 1e-95, 66.94% id in 360 aa, and to Pantoea agglomerans HrcU protein HrcU SWALL:Q47859 (EMBL:X99768) (360 aa) fasta scores: E(): 5.4e-92, 64.34% id in 359 aa. (359 aa)
fliISimilar to Salmonella typhimurium flagellum-specific ATP synthase FliI or Fla AIII or FlaC or stm1972 SWALL:FLII_SALTY (SWALL:P26465) (456 aa) fasta scores: E(): 1.5e-139, 85.24% id in 454 aa. (457 aa)
fliPFlagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (258 aa)
fliQFlagellar biosynthetic protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
flhAFlagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (694 aa)
flhBFlagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa)
virB6Putative conjugal transfer protein; Similar to Escherichia coli VirB6 protein VirB6 SWALL:Q91UX1 (EMBL:AJ297913) (360 aa) fasta scores: E(): 9e-06, 21.12% id in 355 aa. (346 aa)
hasDType I secretion ATP-binding protein; Similar to Pseudomonas fluorescens ABC protein HasD SWALL:Q9RHT2 (EMBL:AB023289) (580 aa) fasta scores: E(): 2.6e-129, 65.58% id in 584 aa, and to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 5.2e-113, 59.47% id in 570 aa. Also similar to ECA2783 (58.719% id. in 562 aa overlap). (619 aa)
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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