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| | SEF28378.1 | Hypothetical protein. (451 aa) |
| | SEF21709.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (578 aa) |
| | SEF21772.1 | Threonine synthase. (369 aa) |
| | SEF21788.1 | Histidinol-phosphatase (PHP family); Belongs to the PHP hydrolase family. HisK subfamily. (279 aa) |
| | SEF21824.1 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase. (440 aa) |
| | SEF21840.1 | Probable phosphomutase, MSMEG_4193 family. (235 aa) |
| | SEF21871.1 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase. (432 aa) |
| | SEF22062.1 | Citrate synthase. (263 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (87 aa) |
| | SEF22206.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1184 aa) |
| | SEF22290.1 | Aconitate hydratase. (937 aa) |
| | SEF19984.1 | Protein of unknown function. (151 aa) |
| | SEF20568.1 | Cysteine synthase A. (313 aa) |
| | SEF20920.1 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (307 aa) |
| | SEF20957.1 | Aromatic acid exporter family member 1. (393 aa) |
| | SEF19701.1 | GntR family transcriptional regulator. (232 aa) |
| | SEF21108.1 | Pentapeptide repeat-containing protein. (310 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (481 aa) |
| | SEF21468.1 | 4-hydroxy-tetrahydrodipicolinate synthase. (276 aa) |
| | SEF19775.1 | Ferredoxin-NADP reductase. (558 aa) |
| | SEF21635.1 | Acetyltransferase (GNAT) family protein. (297 aa) |
| | SEF23316.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (352 aa) |
| | SEF23586.1 | Predicted acetyltransferase, GNAT superfamily. (294 aa) |
| | SEF23140.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1207 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | SEF23960.1 | L-threonine aldolase. (371 aa) |
| | SEF23962.1 | Argininosuccinate lyase. (488 aa) |
| | SEF23177.1 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (600 aa) |
| | SEF24615.1 | Hypothetical protein. (369 aa) |
| | SEF24647.1 | Asparagine synthase (glutamine-hydrolysing). (607 aa) |
| | SEF23239.1 | Diaminopimelate decarboxylase. (429 aa) |
| | SEF24724.1 | Hypothetical protein. (80 aa) |
| | SEF24766.1 | Hypothetical protein. (126 aa) |
| | SEF24895.1 | Hypothetical protein. (241 aa) |
| | SEF24935.1 | Threonine dehydratase. (325 aa) |
| | SEF24976.1 | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. (239 aa) |
| | SEF26312.1 | Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase. (397 aa) |
| | SEF26313.1 | Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist. (308 aa) |
| | SEF26330.1 | Acetyltransferase (GNAT) family protein. (154 aa) |
| | SEF26417.1 | Phosphoserine phosphatase. (409 aa) |
| | SEF26419.1 | Phosphotransferase enzyme family protein. (270 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (412 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (295 aa) |
| | SEF26497.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | SEF26499.1 | Homoserine dehydrogenase. (428 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (476 aa) |
| | SEF26540.1 | Lipocalin-like domain-containing protein. (130 aa) |
| | pqqC | Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (229 aa) |
| | SEF26688.1 | Acetolactate synthase-1/2/3 large subunit. (520 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (368 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | SEF27205.1 | Threonine dehydratase. (400 aa) |
| | SEF27212.1 | Cystathionine gamma-synthase. (385 aa) |
| | SEF27221.1 | Cystathionine beta-synthase. (469 aa) |
| | SEF27226.1 | Hypothetical protein. (309 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (563 aa) |
| | SEF27380.1 | Hypothetical protein. (297 aa) |
| | eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | rsmA | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (278 aa) |
| | SEF27663.1 | Succinyl-diaminopimelate desuccinylase. (370 aa) |
| | SEF28319.1 | Predicted acetyltransferase, GNAT family. (271 aa) |
| | SEF28376.1 | UPF0716 protein FxsA. (158 aa) |
| | SEF38494.1 | Hippurate hydrolase. (408 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa) |
| | SEF38472.1 | Branched-chain amino acid aminotransferase. (367 aa) |
| | SEF38468.1 | DNA-binding transcriptional regulator, GntR family. (249 aa) |
| | SEF38460.1 | Asparagine synthase (glutamine-hydrolysing). (644 aa) |
| | SEF38284.1 | Arginosuccinate synthase. (85 aa) |
| | SEF38354.1 | Phosphoserine phosphatase. (211 aa) |
| | SEF38347.1 | Probable phosphoglycerate mutase. (228 aa) |
| | argH | Argininosuccinate lyase. (471 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (386 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (305 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa) |
| | SEF38286.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | SEF38182.1 | Cystathionine beta-synthase. (472 aa) |
| | SEF38066.1 | Transposase IS116/IS110/IS902 family protein. (397 aa) |
| | SEF38008.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (353 aa) |
| | SEF38005.1 | Branched-chain amino acid aminotransferase. (362 aa) |
| | SEF37997.1 | Anthranilate synthase component 1. (446 aa) |
| | dapA-3 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | SEF37899.1 | Hypothetical protein. (99 aa) |
| | trpB-3 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa) |
| | trpA-2 | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | SEF37527.1 | Hypothetical protein. (181 aa) |
| | SEF37507.1 | Fructose-bisphosphate aldolase, class II. (274 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (762 aa) |
| | SEF37583.1 | GntR family transcriptional regulator. (251 aa) |
| | SEF37452.1 | Threonine dehydratase. (316 aa) |
| | SEF37549.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Belongs to the class-II DAHP synthase family. (416 aa) |
| | SEF37268.1 | Arginase; Belongs to the arginase family. (285 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (450 aa) |
| | SEF37259.1 | Putative hydrolase. (328 aa) |
| | SEF37203.1 | Protein of unknown function. (377 aa) |
| | SEF37360.1 | Glutamate-5-semialdehyde dehydrogenase. (410 aa) |
| | SEF37343.1 | Hypothetical protein. (241 aa) |
| | SEF37333.1 | Histidinol-phosphate aminotransferase. (338 aa) |
| | SEF37316.1 | Glutamate synthase (NADPH/NADH) small chain. (483 aa) |
| | SEF37315.1 | Glutamate synthase (NADPH/NADH) large chain. (1523 aa) |
| | SEF37299.1 | Putative glutamine amidotransferase. (203 aa) |
| | SEF36927.1 | Helix-turn-helix domain-containing protein. (292 aa) |
| | SEF37153.1 | Aminotransferase class I and II. (281 aa) |
| | SEF37129.1 | Asparagine synthase (glutamine-hydrolysing). (495 aa) |
| | SEF37103.1 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (543 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (346 aa) |
| | SEF37100.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (532 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) |
| | SEF37092.1 | Acetolactate synthase, small subunit. (168 aa) |
| | SEF37091.1 | Acetolactate synthase, large subunit. (630 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (614 aa) |
| | SEF37073.1 | Cobalamin-independent synthase, Catalytic domain. (329 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (418 aa) |
| | SEF37005.1 | GntR family transcriptional regulator. (255 aa) |
| | SEF36887.1 | Hypothetical protein. (180 aa) |
| | SEF36867.1 | Hypothetical protein. (368 aa) |
| | SEF36761.1 | Transposase IS116/IS110/IS902 family protein. (273 aa) |
| | SEF36755.1 | Citrate synthase; Belongs to the citrate synthase family. (438 aa) |
| | SEF36731.1 | Citrate synthase; Belongs to the citrate synthase family. (382 aa) |
| | serC | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (374 aa) |
| | SEF36582.1 | Threonine dehydratase. (316 aa) |
| | SEF36326.1 | Hypothetical protein. (192 aa) |
| | SEF36286.1 | Ornithine cyclodeaminase. (300 aa) |
| | SEF36575.1 | Glutamine synthetase. (474 aa) |
| | SEF36400.1 | GntR family transcriptional regulator. (255 aa) |
| | SEF36350.1 | Diaminopimelate decarboxylase. (402 aa) |
| | SEF36251.1 | Glutamine synthetase. (447 aa) |
| | SEF36192.1 | Chorismate mutase. (185 aa) |
| | SEF36137.1 | TIGR02569 family protein. (265 aa) |
| | SEF36045.1 | Succinyldiaminopimelate desuccinylase. (356 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (330 aa) |
| | SEF36038.1 | Succinyldiaminopimelate aminotransferase apoenzyme. (363 aa) |
| | SEF36035.1 | Acetyltransferase (GNAT) family protein. (260 aa) |
| | SEF35986.1 | Histidinol-phosphatase. (261 aa) |
| | SEF35946.1 | Septum formation protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (209 aa) |
| | SEF35482.1 | Hypothetical protein. (254 aa) |
| | SEF35435.1 | Mycothiol synthase. (317 aa) |
| | leuC | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (477 aa) |
| | leuD | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | SEF35784.1 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa) |
| | SEF35783.1 | Arginase; Belongs to the arginase family. (268 aa) |
| | SEF35732.1 | Glutamine synthetase. (448 aa) |
| | SEF35731.1 | Putative glutamine amidotransferase. (236 aa) |
| | glyA-3 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | SEF35721.1 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | SEF35646.1 | Asparagine synthase (glutamine-hydrolysing). (613 aa) |
| | SEF35517.1 | Threonine synthase. (403 aa) |
| | SEF33909.1 | Glutamine synthetase. (452 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa) |
| | trpE | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (519 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa) |
| | hisF | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (263 aa) |
| | SEF35107.1 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (700 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (370 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | SEF35079.1 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | SEF35025.1 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (245 aa) |
| | hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (404 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (143 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa) |
| | SEF34938.1 | GntR family transcriptional regulator. (262 aa) |
| | SEF34927.1 | Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa) |
| | SEF34915.1 | Shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. (275 aa) |
| | SEF33820.1 | Transketolase. (231 aa) |
| | SEF34752.1 | Tat (twin-arginine translocation) pathway signal sequence. (510 aa) |
| | SEF34736.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (547 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (199 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa) |
| | SEF34688.1 | Glutamine synthetase. (450 aa) |
| | SEF34647.1 | Hippurate hydrolase. (424 aa) |
| | SEF34608.1 | GntR family transcriptional regulator. (257 aa) |
| | SEF34574.1 | Hippurate hydrolase. (397 aa) |
| | SEF34385.1 | Phage prohead protease, HK97 family. (330 aa) |
| | SEF34223.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (464 aa) |
| | pfp | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa) |
| | SEF34215.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (275 aa) |
| | SEF33934.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Belongs to the class-II DAHP synthase family. (465 aa) |
| | SEF33928.1 | Glutamate synthase (NADPH/NADH) small chain. (502 aa) |
| | SEF33925.1 | Glutamate synthase (NADPH/NADH) large chain. (1517 aa) |
| | SEF32086.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (556 aa) |
| | SEF33258.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (348 aa) |
| | SEF33247.1 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (457 aa) |
| | SEF33242.1 | Broad specificity phosphatase PhoE. (210 aa) |
| | SEF33222.1 | Ribose 5-phosphate isomerase B. (157 aa) |
| | SEF33080.1 | Acetyltransferase (GNAT) family protein. (184 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (369 aa) |
| | SEF32941.1 | Glucosyl-3-phosphoglycerate phosphatase (pgm family); Belongs to the phosphoglycerate mutase family. (204 aa) |
| | SEF32927.1 | Threonine synthase. (421 aa) |
| | SEF32045.1 | FR47-like protein. (225 aa) |
| | SEF32018.1 | Hypothetical protein. (289 aa) |
| | SEF32016.1 | DNA-binding transcriptional regulator, GntR family. (265 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa) |
| | dapA-2 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (337 aa) |
| | SEF32478.1 | Amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. (171 aa) |
| | SEF31964.1 | Acetyltransferase (GNAT) family protein. (306 aa) |
| | SEF31962.1 | Acetyltransferase (GNAT) family protein. (304 aa) |
| | SEF32245.1 | Hypothetical protein. (289 aa) |
| | SEF32215.1 | 3-isopropylmalate dehydrogenase. (359 aa) |
| | SEF30232.1 | Cystathionine gamma-synthase. (346 aa) |
| | SEF31650.1 | Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa) |
| | SEF31609.1 | Chorismate mutase. (98 aa) |
| | SEF31319.1 | Ribosomal protein S18 acetylase RimI. (159 aa) |
| | SEF31159.1 | Asparagine synthase (glutamine-hydrolysing). (636 aa) |
| | SEF31057.1 | Cysteine synthase A. (359 aa) |
| | rex | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (304 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa) |
| | SEF30921.1 | N-succinyldiaminopimelate aminotransferase. (388 aa) |
| | SEF30898.1 | Helix-turn-helix domain-containing protein. (296 aa) |
| | SEF30891.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (379 aa) |
| | SEF30183.1 | GntR family transcriptional regulator. (260 aa) |
| | SEF30858.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (543 aa) |
| | SEF30798.1 | Prephenate dehydrogenase. (322 aa) |
| | pat | Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (351 aa) |
| | SEF30659.1 | Hypothetical protein. (207 aa) |
| | SEF30424.1 | Prephenate dehydratase. (302 aa) |
| | SEF30299.1 | Protein of unknown function. (179 aa) |
| | SEF30252.1 | Ribose-phosphate pyrophosphokinase. (316 aa) |
| | SEF29735.1 | GntR family transcriptional regulator. (251 aa) |
| | SEF29705.1 | Diaminobutyrate-2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa) |
| | SEF29541.1 | Protein of unknown function. (390 aa) |
| | glyA-2 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | SEF29249.1 | Hypothetical protein. (170 aa) |
| | SEF29170.1 | HAD-superfamily subfamily IB hydrolase, TIGR01490. (276 aa) |
| | SEF29161.1 | Transcriptional regulator, RpiR family. (333 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | SEF29035.1 | Aspartate kinase; Belongs to the aspartokinase family. (421 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (586 aa) |
| | SEF28956.1 | Hippurate hydrolase. (409 aa) |
| | SEF28944.1 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (301 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (447 aa) |
| | SEF28922.1 | GntR family transcriptional regulator. (230 aa) |
| | SEF28859.1 | Acetyltransferase (GNAT) domain-containing protein. (245 aa) |
| | SEF28737.1 | L-threonine aldolase. (340 aa) |
| | SEF28728.1 | Aspartate/methionine/tyrosine aminotransferase. (390 aa) |
| | SEF28655.1 | Hypothetical protein. (134 aa) |
| | SEF28653.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa) |
