(19 nodes) DNA replication origin binding, and DNA replication factor Cdt1 network (Aquilegia coerulea)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5C136	CDT1_C domain-containing protein. (215 aa)
	A0A2G5C8J4	Uncharacterized protein. (355 aa)
	A0A2G5CF49	AAA_16 domain-containing protein. (543 aa)
	A0A2G5CI20	Protein kinase domain-containing protein. (1091 aa)
	A0A2G5CKI0	Zf-primase domain-containing protein. (163 aa)
	A0A2G5CL81	ORC_WH_C domain-containing protein. (740 aa)
	A0A2G5CWL1	Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa)
	A0A2G5CXP5	CDT1 domain-containing protein. (590 aa)
	A0A2G5D585	MCM domain-containing protein; Belongs to the MCM family. (653 aa)
	A0A2G5E0C7	Uncharacterized protein. (346 aa)
	A0A2G5E7J6	Uncharacterized protein. (291 aa)
	A0A2G5E8E2	DNA helicase; Belongs to the MCM family. (649 aa)
	A0A2G5ECL9	Uncharacterized protein. (591 aa)
	A0A2G5EES0	MCM domain-containing protein; Belongs to the MCM family. (725 aa)
	A0A2G5EHN2	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (816 aa)
	A0A2G5ENR4	Zf-primase domain-containing protein. (402 aa)
	A0A2G5ESL0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (752 aa)
	A0A2G5EZ67	AAA domain-containing protein. (437 aa)
	A0A2G5EZ70	Cdc6_C domain-containing protein. (88 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C136	A0A2G5C8J4	CDT1_C domain-containing protein.	Uncharacterized protein.	0.980
A0A2G5C136	A0A2G5CF49	CDT1_C domain-containing protein.	AAA_16 domain-containing protein.	0.974
A0A2G5C136	A0A2G5CI20	CDT1_C domain-containing protein.	Protein kinase domain-containing protein.	0.783
A0A2G5C136	A0A2G5CKI0	CDT1_C domain-containing protein.	Zf-primase domain-containing protein.	0.923
A0A2G5C136	A0A2G5CL81	CDT1_C domain-containing protein.	ORC_WH_C domain-containing protein.	0.972
A0A2G5C136	A0A2G5CWL1	CDT1_C domain-containing protein.	Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.950
A0A2G5C136	A0A2G5D585	CDT1_C domain-containing protein.	MCM domain-containing protein; Belongs to the MCM family.	0.978
A0A2G5C136	A0A2G5E0C7	CDT1_C domain-containing protein.	Uncharacterized protein.	0.966
A0A2G5C136	A0A2G5E7J6	CDT1_C domain-containing protein.	Uncharacterized protein.	0.784
A0A2G5C136	A0A2G5E8E2	CDT1_C domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.966
A0A2G5C136	A0A2G5ECL9	CDT1_C domain-containing protein.	Uncharacterized protein.	0.897
A0A2G5C136	A0A2G5EES0	CDT1_C domain-containing protein.	MCM domain-containing protein; Belongs to the MCM family.	0.996
A0A2G5C136	A0A2G5EHN2	CDT1_C domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.970
A0A2G5C136	A0A2G5ENR4	CDT1_C domain-containing protein.	Zf-primase domain-containing protein.	0.923
A0A2G5C136	A0A2G5ESL0	CDT1_C domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.970
A0A2G5C136	A0A2G5EZ67	CDT1_C domain-containing protein.	AAA domain-containing protein.	0.966
A0A2G5C136	A0A2G5EZ70	CDT1_C domain-containing protein.	Cdc6_C domain-containing protein.	0.971
A0A2G5C8J4	A0A2G5C136	Uncharacterized protein.	CDT1_C domain-containing protein.	0.980
A0A2G5C8J4	A0A2G5CF49	Uncharacterized protein.	AAA_16 domain-containing protein.	0.999
A0A2G5C8J4	A0A2G5CI20	Uncharacterized protein.	Protein kinase domain-containing protein.	0.911