(15 nodes) RNA polymerase II, core complex, and Transcription factor TFIIA complex network (Aquilegia coerulea)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	A0A2G5C775	RPOLD domain-containing protein. (215 aa)
	A0A2G5CKT8	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (284 aa)
	A0A2G5CZV9	Uncharacterized protein. (386 aa)
	A0A2G5D3Y8	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (525 aa)
	A0A2G5D5X0	TFIIF_beta domain-containing protein. (297 aa)
	A0A2G5D817	RNA_pol_L_2 domain-containing protein. (116 aa)
	A0A2G5DJI8	Uncharacterized protein. (205 aa)
	A0A2G5DME7	HTH TFE/IIEalpha-type domain-containing protein. (464 aa)
	A0A2G5DP22	Uncharacterized protein. (51 aa)
	A0A2G5DW58	TFIIS N-terminal domain-containing protein. (360 aa)
	A0A2G5DWL1	RPOL4c domain-containing protein. (139 aa)
	A0A2G5E1G5	Uncharacterized protein. (144 aa)
	A0A2G5E882	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	A0A2G5EG07	Uncharacterized protein. (356 aa)
	A0A2G5EZH6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C775	A0A2G5CKT8	RPOLD domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.981
A0A2G5C775	A0A2G5CZV9	RPOLD domain-containing protein.	Uncharacterized protein.	0.942
A0A2G5C775	A0A2G5D3Y8	RPOLD domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.976
A0A2G5C775	A0A2G5D5X0	RPOLD domain-containing protein.	TFIIF_beta domain-containing protein.	0.966
A0A2G5C775	A0A2G5D817	RPOLD domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.993
A0A2G5C775	A0A2G5DJI8	RPOLD domain-containing protein.	Uncharacterized protein.	0.962
A0A2G5C775	A0A2G5DME7	RPOLD domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.941
A0A2G5C775	A0A2G5DP22	RPOLD domain-containing protein.	Uncharacterized protein.	0.963
A0A2G5C775	A0A2G5DW58	RPOLD domain-containing protein.	TFIIS N-terminal domain-containing protein.	0.967
A0A2G5C775	A0A2G5DWL1	RPOLD domain-containing protein.	RPOL4c domain-containing protein.	0.992
A0A2G5C775	A0A2G5E1G5	RPOLD domain-containing protein.	Uncharacterized protein.	0.996
A0A2G5C775	A0A2G5E882	RPOLD domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.973
A0A2G5C775	A0A2G5EG07	RPOLD domain-containing protein.	Uncharacterized protein.	0.942
A0A2G5C775	A0A2G5EZH6	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.993
A0A2G5CKT8	A0A2G5C775	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	RPOLD domain-containing protein.	0.981
A0A2G5CKT8	A0A2G5CZV9	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	Uncharacterized protein.	0.982
A0A2G5CKT8	A0A2G5D3Y8	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.994
A0A2G5CKT8	A0A2G5D5X0	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	TFIIF_beta domain-containing protein.	0.987
A0A2G5CKT8	A0A2G5D817	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	RNA_pol_L_2 domain-containing protein.	0.991
A0A2G5CKT8	A0A2G5DJI8	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	Uncharacterized protein.	0.953