(33 nodes) Transcription elongation factor complex, and RNA polymerase Rpb1, domain 5 network (Aquilegia coerulea)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5C1P8	Uncharacterized protein. (1006 aa)
	A0A2G5C2F5	Uncharacterized protein. (1065 aa)
	A0A2G5C781	RPOLD domain-containing protein. (346 aa)
	A0A2G5C7J2	TPR_REGION domain-containing protein. (1087 aa)
	A0A2G5CCJ9	Uncharacterized protein. (1028 aa)
	A0A2G5CD60	Uncharacterized protein. (175 aa)
	A0A2G5CIZ7	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (89 aa)
	A0A2G5CKM6	Uncharacterized protein. (409 aa)
	A0A2G5CST5	Uncharacterized protein. (1505 aa)
	A0A2G5CW55	Transcription elongation factor SPT5. (1025 aa)
	A0A2G5CYK1	Uncharacterized protein. (1225 aa)
	A0A2G5D342	Spt4 domain-containing protein. (73 aa)
	A0A2G5D3X8	Tyrosinase_Cu-bd domain-containing protein. (593 aa)
	A0A2G5D4V9	Uncharacterized protein. (370 aa)
	A0A2G5DCN4	Uncharacterized protein. (773 aa)
	A0A2G5DEH5	Transcription elongation factor SPT4 homolog; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex; Belongs to the SPT4 family. (115 aa)
	A0A2G5DIF6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1928 aa)
	A0A2G5DJE4	RNA_pol_Rpb1_1 domain-containing protein. (145 aa)
	A0A2G5E0C8	Uncharacterized protein. (465 aa)
	A0A2G5E4Y4	Plus3 domain-containing protein. (639 aa)
	A0A2G5EBW9	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1722 aa)
	A0A2G5EHW6	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1239 aa)
	A0A2G5EL30	Uncharacterized protein. (665 aa)
	A0A2G5EME2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1802 aa)
	A0A2G5EWG0	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (105 aa)
	A0A2G5EXB2	Uncharacterized protein. (712 aa)
	A0A2G5EYT9	Uncharacterized protein. (73 aa)
	A0A2G5F373	Uncharacterized protein. (263 aa)
	A0A2G5F389	Uncharacterized protein. (181 aa)
	A0A2G5F3F0	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (638 aa)
	A0A2G5F3F5	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (175 aa)
	A0A2G5F3P9	RPOL4c domain-containing protein. (235 aa)
	A0A2G5F4W2	Uncharacterized protein. (618 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C1P8	A0A2G5C781	Uncharacterized protein.	RPOLD domain-containing protein.	0.939
A0A2G5C1P8	A0A2G5C7J2	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.967
A0A2G5C1P8	A0A2G5CCJ9	Uncharacterized protein.	Uncharacterized protein.	0.831
A0A2G5C1P8	A0A2G5CD60	Uncharacterized protein.	Uncharacterized protein.	0.796
A0A2G5C1P8	A0A2G5CIZ7	Uncharacterized protein.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.692
A0A2G5C1P8	A0A2G5CKM6	Uncharacterized protein.	Uncharacterized protein.	0.981
A0A2G5C1P8	A0A2G5CST5	Uncharacterized protein.	Uncharacterized protein.	0.844
A0A2G5C1P8	A0A2G5CW55	Uncharacterized protein.	Transcription elongation factor SPT5.	0.844
A0A2G5C1P8	A0A2G5D342	Uncharacterized protein.	Spt4 domain-containing protein.	0.939
A0A2G5C1P8	A0A2G5D3X8	Uncharacterized protein.	Tyrosinase_Cu-bd domain-containing protein.	0.661
A0A2G5C1P8	A0A2G5D4V9	Uncharacterized protein.	Uncharacterized protein.	0.853
A0A2G5C1P8	A0A2G5DCN4	Uncharacterized protein.	Uncharacterized protein.	0.844
A0A2G5C1P8	A0A2G5DEH5	Uncharacterized protein.	Transcription elongation factor SPT4 homolog; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex; Belongs to the SPT4 family.	0.939
A0A2G5C1P8	A0A2G5DIF6	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.792
A0A2G5C1P8	A0A2G5DJE4	Uncharacterized protein.	RNA_pol_Rpb1_1 domain-containing protein.	0.831
A0A2G5C1P8	A0A2G5E0C8	Uncharacterized protein.	Uncharacterized protein.	0.844
A0A2G5C1P8	A0A2G5E4Y4	Uncharacterized protein.	Plus3 domain-containing protein.	0.866
A0A2G5C1P8	A0A2G5EBW9	Uncharacterized protein.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.968
A0A2G5C1P8	A0A2G5EHW6	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.844
A0A2G5C1P8	A0A2G5EL30	Uncharacterized protein.	Uncharacterized protein.	0.844