(32 nodes) MAPK cascade, and MAP kinase phosphatase activity network (Aquilegia coerulea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5C2E9	Uncharacterized protein. (193 aa)
	A0A2G5CAT2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (473 aa)
	A0A2G5CBD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
	A0A2G5CBZ0	Protein kinase domain-containing protein. (460 aa)
	A0A2G5CIP2	Protein kinase domain-containing protein. (575 aa)
	A0A2G5CLB1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
	A0A2G5CSI8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (459 aa)
	A0A2G5CTE6	BHLH domain-containing protein. (350 aa)
	A0A2G5D1A2	DNL-type domain-containing protein. (196 aa)
	A0A2G5D205	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (403 aa)
	A0A2G5D5A1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	A0A2G5D5E9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (366 aa)
	A0A2G5D6X5	Protein kinase domain-containing protein. (397 aa)
	A0A2G5DB88	Protein kinase domain-containing protein. (363 aa)
	A0A2G5DD47	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (367 aa)
	A0A2G5DHJ1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (359 aa)
	A0A2G5DMW0	Protein kinase domain-containing protein. (697 aa)
	A0A2G5DUR5	Uncharacterized protein. (343 aa)
	A0A2G5DVD1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
	A0A2G5DWA3	Protein kinase domain-containing protein. (669 aa)
	A0A2G5E029	Protein kinase domain-containing protein. (653 aa)
	A0A2G5E0N0	Protein kinase domain-containing protein. (898 aa)
	A0A2G5E3C0	Uncharacterized protein. (705 aa)
	A0A2G5E7N4	Uncharacterized protein. (518 aa)
	A0A2G5EAI8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	A0A2G5EHQ9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
	A0A2G5EJI3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (370 aa)
	A0A2G5ES64	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	A0A2G5ESK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (330 aa)
	A0A2G5EY23	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (357 aa)
	A0A2G5F240	Protein kinase domain-containing protein. (364 aa)
	A0A2G5F788	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (319 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C2E9	A0A2G5CLB1	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.822
A0A2G5C2E9	A0A2G5CSI8	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.583
A0A2G5C2E9	A0A2G5D205	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.625
A0A2G5C2E9	A0A2G5D5A1	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.822
A0A2G5C2E9	A0A2G5D5E9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.539
A0A2G5C2E9	A0A2G5DUR5	Uncharacterized protein.	Uncharacterized protein.	0.699
A0A2G5C2E9	A0A2G5EAI8	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.504
A0A2G5C2E9	A0A2G5EJI3	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.504
A0A2G5C2E9	A0A2G5ES64	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.504
A0A2G5CAT2	A0A2G5CBD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.513
A0A2G5CAT2	A0A2G5D6X5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.495
A0A2G5CAT2	A0A2G5DD47	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.507
A0A2G5CAT2	A0A2G5DHJ1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.505
A0A2G5CAT2	A0A2G5DVD1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.881
A0A2G5CAT2	A0A2G5E029	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.451
A0A2G5CAT2	A0A2G5E3C0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.513
A0A2G5CAT2	A0A2G5E7N4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.919
A0A2G5CAT2	A0A2G5EAI8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.402
A0A2G5CAT2	A0A2G5ES64	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.402
A0A2G5CAT2	A0A2G5ESK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.494