(12 nodes) Mitotic DNA replication checkpoint signaling network (Aquilegia coerulea)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5EZ70	Cdc6_C domain-containing protein. (88 aa)
	A0A2G5CLS9	Cell division control protein; Belongs to the CDC6/cdc18 family. (524 aa)
	A0A2G5EMI0	Checkpoint protein; Belongs to the HUS1 family. (317 aa)
	A0A2G5EI65	Uncharacterized protein. (617 aa)
	A0A2G5DYJ7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (813 aa)
	A0A2G5EHN2	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (816 aa)
	A0A2G5E068	Uncharacterized protein. (1004 aa)
	A0A2G5EZ67	AAA domain-containing protein. (437 aa)
	A0A2G5ESL0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (752 aa)
	A0A2G5DVR1	AAA domain-containing protein. (1447 aa)
	A0A2G5DVM9	Uncharacterized protein. (1077 aa)
	A0A2G5CQ37	Uncharacterized protein. (358 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5CLS9	A0A2G5DYJ7	Cell division control protein; Belongs to the CDC6/cdc18 family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.981
A0A2G5CLS9	A0A2G5EHN2	Cell division control protein; Belongs to the CDC6/cdc18 family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.980
A0A2G5CLS9	A0A2G5EI65	Cell division control protein; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.494
A0A2G5CLS9	A0A2G5ESL0	Cell division control protein; Belongs to the CDC6/cdc18 family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.981
A0A2G5DVM9	A0A2G5DVR1	Uncharacterized protein.	AAA domain-containing protein.	0.475
A0A2G5DVM9	A0A2G5EI65	Uncharacterized protein.	Uncharacterized protein.	0.889
A0A2G5DVM9	A0A2G5EMI0	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.855
A0A2G5DVR1	A0A2G5DVM9	AAA domain-containing protein.	Uncharacterized protein.	0.475
A0A2G5DVR1	A0A2G5DYJ7	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.428
A0A2G5DVR1	A0A2G5EHN2	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.428
A0A2G5DVR1	A0A2G5EI65	AAA domain-containing protein.	Uncharacterized protein.	0.952
A0A2G5DVR1	A0A2G5EMI0	AAA domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.722
A0A2G5DVR1	A0A2G5ESL0	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.428
A0A2G5DYJ7	A0A2G5CLS9	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.981
A0A2G5DYJ7	A0A2G5DVR1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.428
A0A2G5DYJ7	A0A2G5EZ67	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.981
A0A2G5DYJ7	A0A2G5EZ70	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Cdc6_C domain-containing protein.	0.980
A0A2G5EHN2	A0A2G5CLS9	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.980
A0A2G5EHN2	A0A2G5DVR1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.428
A0A2G5EHN2	A0A2G5EZ67	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.981