(51 nodes) RNA polymerase II, holoenzyme network (Aquilegia coerulea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5CMC9	Uncharacterized protein. (1907 aa)
	A0A2G5FAW7	MAT1 domain-containing protein. (196 aa)
	A0A2G5F6E8	Peptidase_M1 domain-containing protein. (1380 aa)
	A0A2G5F683	HTH TFE/IIEalpha-type domain-containing protein. (473 aa)
	A0A2G5F4W2	Uncharacterized protein. (618 aa)
	A0A2G5CZV9	Uncharacterized protein. (386 aa)
	A0A2G5CZ76	TAFII28 domain-containing protein. (258 aa)
	A0A2G5CRB8	Uncharacterized protein. (396 aa)
	A0A2G5CR95	TBP-binding domain-containing protein. (271 aa)
	A0A2G5CR36	Uncharacterized protein. (812 aa)
	A0A2G5CPM1	MAT1 domain-containing protein. (196 aa)
	A0A2G5DFK4	TAFII55_N domain-containing protein. (200 aa)
	A0A2G5DGM5	Uncharacterized protein. (668 aa)
	A0A2G5DHE3	WD_REPEATS_REGION domain-containing protein. (321 aa)
	A0A2G5DM18	CYCLIN domain-containing protein; Belongs to the cyclin family. (334 aa)
	A0A2G5DME7	HTH TFE/IIEalpha-type domain-containing protein. (464 aa)
	A0A2G5DNV2	General transcription factor IIH subunit. (427 aa)
	A0A2G5DNZ1	Plus3 domain-containing protein. (1145 aa)
	A0A2G5D5X0	TFIIF_beta domain-containing protein. (297 aa)
	A0A2G5D7V7	HTH TFE/IIEalpha-type domain-containing protein. (472 aa)
	A0A2G5D817	RNA_pol_L_2 domain-containing protein. (116 aa)
	A0A2G5D1X5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	A0A2G5C7J2	TPR_REGION domain-containing protein. (1087 aa)
	A0A2G5CC85	Uncharacterized protein. (213 aa)
	A0A2G5DWG9	Protein kinase domain-containing protein. (582 aa)
	A0A2G5DWL1	RPOL4c domain-containing protein. (139 aa)
	A0A2G5E4Y4	Plus3 domain-containing protein. (639 aa)
	A0A2G5E882	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	A0A2G5EFM8	Uncharacterized protein. (331 aa)
	A0A2G5EFP0	Uncharacterized protein. (963 aa)
	A0A2G5EFR8	TFIID_20kDa domain-containing protein. (662 aa)
	A0A2G5EG07	Uncharacterized protein. (356 aa)
	A0A2G5EHW6	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1239 aa)
	A0A2G5EJN3	Uncharacterized protein. (951 aa)
	A0A2G5EJQ5	Plus3 domain-containing protein. (714 aa)
	A0A2G5ELX0	Uncharacterized protein. (177 aa)
	A0A2G5EME2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1802 aa)
	A0A2G5EN62	Uncharacterized protein. (1533 aa)
	A0A2G5ENC7	Uncharacterized protein. (255 aa)
	A0A2G5D3Y8	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (525 aa)
	A0A2G5ET36	C2H2-type domain-containing protein. (418 aa)
	A0A2G5ETF3	TFIID_20kDa domain-containing protein. (321 aa)
	A0A2G5EXB2	Uncharacterized protein. (712 aa)
	A0A2G5EZH6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa)
	A0A2G5F373	Uncharacterized protein. (263 aa)
	A0A2G5F389	Uncharacterized protein. (181 aa)
	A0A2G5CHI9	Uncharacterized protein. (927 aa)
	A0A2G5CKM6	Uncharacterized protein. (409 aa)
	A0A2G5CKP0	Uncharacterized protein. (911 aa)
	A0A2G5CKT8	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (284 aa)
	A0A2G5CLH8	Uncharacterized protein. (531 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C7J2	A0A2G5CC85	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.858
A0A2G5C7J2	A0A2G5CKM6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
A0A2G5C7J2	A0A2G5D1X5	TPR_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.526
A0A2G5C7J2	A0A2G5D3Y8	TPR_REGION domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.419
A0A2G5C7J2	A0A2G5D817	TPR_REGION domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.952
A0A2G5C7J2	A0A2G5DGM5	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.492
A0A2G5C7J2	A0A2G5DHE3	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.819
A0A2G5C7J2	A0A2G5DWL1	TPR_REGION domain-containing protein.	RPOL4c domain-containing protein.	0.943
A0A2G5C7J2	A0A2G5E4Y4	TPR_REGION domain-containing protein.	Plus3 domain-containing protein.	0.982
A0A2G5C7J2	A0A2G5EHW6	TPR_REGION domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.872
A0A2G5C7J2	A0A2G5ELX0	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.858
A0A2G5C7J2	A0A2G5EME2	TPR_REGION domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.767
A0A2G5C7J2	A0A2G5EXB2	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
A0A2G5C7J2	A0A2G5EZH6	TPR_REGION domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.943
A0A2G5C7J2	A0A2G5F373	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.982
A0A2G5C7J2	A0A2G5F389	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.858
A0A2G5C7J2	A0A2G5F4W2	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
A0A2G5CC85	A0A2G5C7J2	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.858
A0A2G5CC85	A0A2G5CHI9	Uncharacterized protein.	Uncharacterized protein.	0.608
A0A2G5CC85	A0A2G5CKM6	Uncharacterized protein.	Uncharacterized protein.	0.846