(40 nodes) Von Willebrand factor A-like domain superfamily network (Aquilegia coerulea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5CNK1	Uncharacterized protein. (581 aa)
	A0A2G5C0I8	Uncharacterized protein. (133 aa)
	A0A2G5F885	Uncharacterized protein. (607 aa)
	A0A2G5C8M7	VWFA domain-containing protein. (759 aa)
	A0A2G5CAF6	Uncharacterized protein. (742 aa)
	A0A2G5CC94	RING-type domain-containing protein. (421 aa)
	A0A2G5CEV5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (776 aa)
	A0A2G5CG94	RING-type domain-containing protein. (450 aa)
	A0A2G5CJP5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (792 aa)
	A0A2G5CP22	Uncharacterized protein. (266 aa)
	A0A2G5CTN9	Uncharacterized protein. (1009 aa)
	A0A2G5CX97	SAP domain-containing protein. (640 aa)
	A0A2G5D298	RING-type domain-containing protein. (403 aa)
	A0A2G5D320	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (874 aa)
	A0A2G5D7G3	Uncharacterized protein. (516 aa)
	A0A2G5D7G4	C2 domain-containing protein. (597 aa)
	A0A2G5D810	Uncharacterized protein. (811 aa)
	A0A2G5DEE5	Uncharacterized protein. (567 aa)
	A0A2G5DFF0	Uncharacterized protein. (266 aa)
	A0A2G5DH67	Uncharacterized protein. (267 aa)
	A0A2G5DHG1	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5451 aa)
	A0A2G5DM17	RING-type domain-containing protein. (412 aa)
	A0A2G5DM45	Uncharacterized protein. (589 aa)
	A0A2G5DNG2	ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. (689 aa)
	A0A2G5DNV2	General transcription factor IIH subunit. (427 aa)
	A0A2G5DQ28	Uncharacterized protein. (602 aa)
	A0A2G5DT06	Uncharacterized protein. (303 aa)
	A0A2G5DYD9	Mg-protoporphyrin IX chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. Belongs to the Mg-chelatase subunits D/I family. (766 aa)
	A0A2G5E756	RING-type domain-containing protein. (439 aa)
	A0A2G5ELR9	Uncharacterized protein. (1090 aa)
	A0A2G5ENH8	VWFA domain-containing protein. (401 aa)
	A0A2G5ERE3	RING-type domain-containing protein. (503 aa)
	A0A2G5ERT4	Uncharacterized protein. (548 aa)
	A0A2G5ESU2	ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. (669 aa)
	A0A2G5ESW3	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (762 aa)
	A0A2G5ET36	C2H2-type domain-containing protein. (418 aa)
	A0A2G5F962	RING-type domain-containing protein. (443 aa)
	A0A2G5FAA0	Uncharacterized protein. (627 aa)
	A0A2G5FAH7	Uncharacterized protein. (690 aa)
	A0A2G5FCG1	Uncharacterized protein. (175 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C0I8	A0A2G5DNV2	Uncharacterized protein.	General transcription factor IIH subunit.	0.975
A0A2G5C0I8	A0A2G5ET36	Uncharacterized protein.	C2H2-type domain-containing protein.	0.975
A0A2G5C0I8	A0A2G5FCG1	Uncharacterized protein.	Uncharacterized protein.	0.695
A0A2G5CAF6	A0A2G5CEV5	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.963
A0A2G5CAF6	A0A2G5CJP5	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.963
A0A2G5CAF6	A0A2G5D320	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.963
A0A2G5CAF6	A0A2G5ELR9	Uncharacterized protein.	Uncharacterized protein.	0.993
A0A2G5CAF6	A0A2G5ESW3	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.963
A0A2G5CEV5	A0A2G5CAF6	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.963
A0A2G5CEV5	A0A2G5CJP5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.899
A0A2G5CEV5	A0A2G5CTN9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.985
A0A2G5CEV5	A0A2G5D320	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.518
A0A2G5CEV5	A0A2G5ELR9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.991
A0A2G5CJP5	A0A2G5CAF6	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.963
A0A2G5CJP5	A0A2G5CEV5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.899
A0A2G5CJP5	A0A2G5CTN9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.988
A0A2G5CJP5	A0A2G5D320	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.403
A0A2G5CJP5	A0A2G5ELR9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.992
A0A2G5CJP5	A0A2G5ESW3	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.899
A0A2G5CTN9	A0A2G5CEV5	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.985