(25 nodes) Toll Like Receptor TLR6:TLR2 Cascade network (Aquilegia coerulea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5F2Z6	Serine/threonine-protein phosphatase. (306 aa)
	A0A2G5FCD2	Uncharacterized protein. (109 aa)
	A0A2G5C0D8	TMEM189_B_dmain domain-containing protein. (209 aa)
	A0A2G5C4D0	Ubiquitin-like domain-containing protein. (128 aa)
	A0A2G5C522	Uncharacterized protein. (958 aa)
	A0A2G5C853	TMEM189_B_dmain domain-containing protein. (245 aa)
	A0A2G5C865	TMEM189_B_dmain domain-containing protein. (305 aa)
	A0A2G5CEY5	PsaL domain-containing protein. (216 aa)
	A0A2G5CEY6	Uncharacterized protein. (201 aa)
	A0A2G5CNT7	TMEM189_B_dmain domain-containing protein. (240 aa)
	A0A2G5CQ62	Uncharacterized protein. (1187 aa)
	A0A2G5D043	Uncharacterized protein. (135 aa)
	A0A2G5D3M8	Uncharacterized protein. (213 aa)
	A0A2G5D4F8	COR domain-containing protein. (1377 aa)
	A0A2G5D851	Uncharacterized protein. (596 aa)
	A0A2G5D9X2	Serine/threonine-protein phosphatase. (306 aa)
	A0A2G5DA24	Uncharacterized protein. (106 aa)
	A0A2G5DTV1	Uncharacterized protein. (418 aa)
	A0A2G5EDT7	Serine/threonine-protein phosphatase. (313 aa)
	A0A2G5EW95	Serine/threonine-protein phosphatase. (313 aa)
	A0A2G5EYJ5	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2G5EZ15	Uncharacterized protein. (230 aa)
	A0A2G5F1J1	Ubiquitin-like domain-containing protein. (157 aa)
	A0A2G5F2I6	Uncharacterized protein. (617 aa)
	A0A2G5F2I9	Uncharacterized protein. (105 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C0D8	A0A2G5C4D0	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.794
A0A2G5C0D8	A0A2G5EYJ5	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.794
A0A2G5C0D8	A0A2G5F1J1	TMEM189_B_dmain domain-containing protein.	Ubiquitin-like domain-containing protein.	0.794
A0A2G5C4D0	A0A2G5C0D8	Ubiquitin-like domain-containing protein.	TMEM189_B_dmain domain-containing protein.	0.794
A0A2G5C4D0	A0A2G5C522	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.505
A0A2G5C4D0	A0A2G5C853	Ubiquitin-like domain-containing protein.	TMEM189_B_dmain domain-containing protein.	0.794
A0A2G5C4D0	A0A2G5C865	Ubiquitin-like domain-containing protein.	TMEM189_B_dmain domain-containing protein.	0.794
A0A2G5C4D0	A0A2G5CNT7	Ubiquitin-like domain-containing protein.	TMEM189_B_dmain domain-containing protein.	0.794
A0A2G5C4D0	A0A2G5CQ62	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.505
A0A2G5C4D0	A0A2G5D4F8	Ubiquitin-like domain-containing protein.	COR domain-containing protein.	0.584
A0A2G5C4D0	A0A2G5D851	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.505
A0A2G5C4D0	A0A2G5D9X2	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.531
A0A2G5C4D0	A0A2G5DA24	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.584
A0A2G5C4D0	A0A2G5DTV1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.505
A0A2G5C4D0	A0A2G5EDT7	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.531
A0A2G5C4D0	A0A2G5EW95	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.531
A0A2G5C4D0	A0A2G5F2I6	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.584
A0A2G5C4D0	A0A2G5F2I9	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.584
A0A2G5C4D0	A0A2G5F2Z6	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.531
A0A2G5C4D0	A0A2G5FCD2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.531