(41 nodes) Translesion synthesis by POLK network (Aquilegia coerulea)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	A0A2G5CWM3	AAA domain-containing protein. (338 aa)
	A0A2G5FCH2	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (896 aa)
	A0A2G5F5E8	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (623 aa)
	A0A2G5F1J1	Ubiquitin-like domain-containing protein. (157 aa)
	A0A2G5F0S8	DNA polymerase. (1819 aa)
	A0A2G5EYJ5	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2G5EVS5	AAA domain-containing protein. (354 aa)
	A0A2G5ET69	Uncharacterized protein. (293 aa)
	A0A2G5ES58	Uncharacterized protein. (549 aa)
	A0A2G5ER93	Uncharacterized protein. (206 aa)
	A0A2G5ER57	Uncharacterized protein. (211 aa)
	A0A2G5EFC0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (267 aa)
	A0A2G5EF58	Replication factor C subunit 1. (977 aa)
	A0A2G5EAE4	Uncharacterized protein. (810 aa)
	A0A2G5E6W6	AAA domain-containing protein. (1043 aa)
	A0A2G5E4W3	REPA_OB_2 domain-containing protein. (265 aa)
	A0A2G5E1B6	AAA domain-containing protein. (334 aa)
	A0A2G5DVR1	AAA domain-containing protein. (1447 aa)
	A0A2G5DVF6	AAA domain-containing protein. (361 aa)
	A0A2G5DU40	AAA domain-containing protein. (1232 aa)
	A0A2G5DPP1	NAC domain-containing protein. (269 aa)
	A0A2G5DKU2	DNA_pol3_gamma3 domain-containing protein. (932 aa)
	A0A2G5DI32	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (637 aa)
	A0A2G5DI13	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (637 aa)
	A0A2G5DFK8	NAC domain-containing protein. (573 aa)
	A0A2G5DFK1	NAC domain-containing protein. (570 aa)
	A0A2G5DBF2	Uncharacterized protein. (295 aa)
	A0A2G5D2T9	HORMA domain-containing protein. (207 aa)
	A0A2G5D1H5	Uncharacterized protein. (242 aa)
	A0A2G5CYQ7	NAC domain-containing protein. (286 aa)
	A0A2G5CWC3	Uncharacterized protein. (136 aa)
	A0A2G5CRL4	AAA domain-containing protein. (1199 aa)
	A0A2G5CQQ0	OB domain-containing protein. (314 aa)
	A0A2G5CPQ6	UmuC domain-containing protein. (537 aa)
	A0A2G5CPN8	UmuC domain-containing protein. (692 aa)
	A0A2G5CNW3	Uncharacterized protein. (482 aa)
	A0A2G5CDN3	Uncharacterized protein. (694 aa)
	A0A2G5CDL1	Uncharacterized protein. (226 aa)
	A0A2G5C7K4	AAA domain-containing protein. (341 aa)
	A0A2G5C6Z2	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1164 aa)
	A0A2G5C4D0	Ubiquitin-like domain-containing protein. (128 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C4D0	A0A2G5C6Z2	Ubiquitin-like domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.930
A0A2G5C4D0	A0A2G5C7K4	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.511
A0A2G5C4D0	A0A2G5CDN3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.671
A0A2G5C4D0	A0A2G5CPN8	Ubiquitin-like domain-containing protein.	UmuC domain-containing protein.	0.671
A0A2G5C4D0	A0A2G5CPQ6	Ubiquitin-like domain-containing protein.	UmuC domain-containing protein.	0.671
A0A2G5C4D0	A0A2G5CRL4	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.511
A0A2G5C4D0	A0A2G5CWC3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.511
A0A2G5C4D0	A0A2G5CWM3	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.628
A0A2G5C4D0	A0A2G5D2T9	Ubiquitin-like domain-containing protein.	HORMA domain-containing protein.	0.680
A0A2G5C4D0	A0A2G5DBF2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.511
A0A2G5C4D0	A0A2G5DKU2	Ubiquitin-like domain-containing protein.	DNA_pol3_gamma3 domain-containing protein.	0.511
A0A2G5C4D0	A0A2G5DU40	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.511
A0A2G5C4D0	A0A2G5DVF6	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.688
A0A2G5C4D0	A0A2G5DVR1	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.629
A0A2G5C4D0	A0A2G5E1B6	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.628
A0A2G5C4D0	A0A2G5E6W6	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.511
A0A2G5C4D0	A0A2G5EAE4	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.605
A0A2G5C4D0	A0A2G5EF58	Ubiquitin-like domain-containing protein.	Replication factor C subunit 1.	0.629
A0A2G5C4D0	A0A2G5EFC0	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.956
A0A2G5C4D0	A0A2G5ES58	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.605