(77 nodes) Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S network (Aquilegia coerulea)

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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co-expression

protein homology

Your Input:
	A0A2G5EMY2	40S ribosomal protein S27. (86 aa)
	A0A2G5ERT2	Epimerase domain-containing protein. (353 aa)
	A0A2G5ERT5	Epimerase domain-containing protein. (340 aa)
	A0A2G5ERT7	Epimerase domain-containing protein. (354 aa)
	A0A2G5EU64	TF-B3 domain-containing protein. (78 aa)
	A0A2G5EU74	TF-B3 domain-containing protein. (165 aa)
	A0A2G5EUH5	TF-B3 domain-containing protein. (183 aa)
	A0A2G5EUI4	Uncharacterized protein. (219 aa)
	A0A2G5F3X1	Epimerase domain-containing protein. (329 aa)
	A0A2G5F8E4	Uncharacterized protein; Belongs to the DEAD box helicase family. (421 aa)
	A0A2G5C4L1	Epimerase domain-containing protein. (321 aa)
	A0A2G5C4N3	Epimerase domain-containing protein. (323 aa)
	A0A2G5C6A3	TF-B3 domain-containing protein. (178 aa)
	A0A2G5C8G3	Uncharacterized protein. (573 aa)
	A0A2G5C9P1	Helicase C-terminal domain-containing protein. (481 aa)
	A0A2G5CED5	Helicase C-terminal domain-containing protein. (338 aa)
	A0A2G5CEY2	Helicase C-terminal domain-containing protein. (416 aa)
	A0A2G5CFL9	Helicase C-terminal domain-containing protein. (239 aa)
	A0A2G5CGC2	40S ribosomal protein S27. (87 aa)
	A0A2G5CGM9	Uncharacterized protein. (618 aa)
	A0A2G5CJX2	Uncharacterized protein. (431 aa)
	A0A2G5CNZ7	Epimerase domain-containing protein. (319 aa)
	A0A2G5CRF6	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (147 aa)
	A0A2G5CS58	Uncharacterized protein. (239 aa)
	A0A2G5CT69	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (145 aa)
	A0A2G5CY77	Uncharacterized protein. (82 aa)
	A0A2G5CZN7	Epimerase domain-containing protein. (335 aa)
	A0A2G5D1Z1	Epimerase domain-containing protein. (333 aa)
	A0A2G5D874	Epimerase domain-containing protein. (319 aa)
	A0A2G5D987	Uncharacterized protein. (508 aa)
	A0A2G5DAL8	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (364 aa)
	A0A2G5DB60	Uncharacterized protein. (263 aa)
	A0A2G5DDC2	Uncharacterized protein. (423 aa)
	A0A2G5DDC5	Uncharacterized protein. (441 aa)
	A0A2G5DHM1	Uncharacterized protein. (222 aa)
	A0A2G5DIM1	Uncharacterized protein. (259 aa)
	A0A2G5DIR9	Helicase C-terminal domain-containing protein. (537 aa)
	A0A2G5DKP3	Uncharacterized protein. (774 aa)
	A0A2G5DMR5	Uncharacterized protein. (428 aa)
	A0A2G5DTW3	NAC domain-containing protein. (286 aa)
	A0A2G5DU21	Epimerase domain-containing protein. (257 aa)
	A0A2G5DVH1	TF-B3 domain-containing protein. (149 aa)
	A0A2G5DVI8	Uncharacterized protein. (272 aa)
	A0A2G5DVJ8	Uncharacterized protein. (257 aa)
	A0A2G5DVK9	Uncharacterized protein. (396 aa)
	A0A2G5DW99	TF-B3 domain-containing protein. (260 aa)
	A0A2G5DY28	Uncharacterized protein. (526 aa)
	A0A2G5DY42	Epimerase domain-containing protein. (338 aa)
	A0A2G5DZE8	Epimerase domain-containing protein. (329 aa)
	A0A2G5E2L7	Epimerase domain-containing protein. (328 aa)
	A0A2G5E561	Uncharacterized protein. (493 aa)
	A0A2G5E9E8	TF-B3 domain-containing protein. (211 aa)
	A0A2G5E9G0	Uncharacterized protein. (126 aa)
	A0A2G5E9G3	Uncharacterized protein. (623 aa)
	A0A2G5E9H5	Uncharacterized protein. (311 aa)
	A0A2G5E9H9	Uncharacterized protein. (285 aa)
	A0A2G5EA17	TF-B3 domain-containing protein. (216 aa)
	A0A2G5EAF9	Epimerase domain-containing protein. (367 aa)
	A0A2G5ECJ6	Uncharacterized protein. (176 aa)
	A0A2G5ECK4	Epimerase domain-containing protein. (332 aa)
	A0A2G5ECN8	Epimerase domain-containing protein. (386 aa)
	A0A2G5ECQ9	Epimerase domain-containing protein. (326 aa)
	A0A2G5ED48	Epimerase domain-containing protein. (330 aa)
	A0A2G5EFU8	Uncharacterized protein. (221 aa)
	A0A2G5EFW9	Uncharacterized protein. (288 aa)
	A0A2G5EK48	Uncharacterized protein. (285 aa)
	A0A2G5EK50	Uncharacterized protein. (292 aa)
	A0A2G5EKB6	Uncharacterized protein. (480 aa)
	A0A2G5EKD5	Uncharacterized protein. (413 aa)
	A0A2G5EKY2	Epimerase domain-containing protein. (341 aa)
	A0A2G5EQV5	TF-B3 domain-containing protein. (142 aa)
	A0A2G5C284	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (300 aa)
	A0A2G5C2Y8	Epimerase domain-containing protein. (204 aa)
	A0A2G5C2Z4	Epimerase domain-containing protein. (226 aa)
	A0A2G5C306	Epimerase domain-containing protein. (338 aa)
	A0A2G5C3S8	Epimerase domain-containing protein. (218 aa)
	A0A2G5C406	Epimerase domain-containing protein. (329 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C6A3	A0A2G5CRF6	TF-B3 domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5C6A3	A0A2G5CT69	TF-B3 domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5C8G3	A0A2G5CRF6	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5C8G3	A0A2G5CT69	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5C9P1	A0A2G5CRF6	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5C9P1	A0A2G5CT69	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CED5	A0A2G5CRF6	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CED5	A0A2G5CT69	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CEY2	A0A2G5CRF6	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CEY2	A0A2G5CT69	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CFL9	A0A2G5CRF6	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CFL9	A0A2G5CT69	Helicase C-terminal domain-containing protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CGC2	A0A2G5CRF6	40S ribosomal protein S27.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5CGC2	A0A2G5CT69	40S ribosomal protein S27.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5CGM9	A0A2G5CRF6	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5CGM9	A0A2G5CT69	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.659
A0A2G5CJX2	A0A2G5CRF6	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CJX2	A0A2G5CT69	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.464
A0A2G5CRF6	A0A2G5C6A3	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	TF-B3 domain-containing protein.	0.659
A0A2G5CRF6	A0A2G5C8G3	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Uncharacterized protein.	0.464