(13 nodes) Death Receptor Signaling network (Aquilegia coerulea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2G5F6K4	WD_REPEATS_REGION domain-containing protein. (321 aa)
	A0A2G5F5B8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (438 aa)
	A0A2G5F1J1	Ubiquitin-like domain-containing protein. (157 aa)
	A0A2G5EYJ5	Ubiquitin-like domain-containing protein. (156 aa)
	A0A2G5E3I1	Uncharacterized protein. (391 aa)
	A0A2G5E0Q8	PA domain-containing protein. (545 aa)
	A0A2G5DXP2	PUA domain-containing protein. (439 aa)
	A0A2G5DE04	Uncharacterized protein. (149 aa)
	A0A2G5F7N7	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
	A0A2G5F728	Ncstrn_small domain-containing protein. (665 aa)
	A0A2G5CQI4	WD_REPEATS_REGION domain-containing protein. (318 aa)
	A0A2G5C4D0	Ubiquitin-like domain-containing protein. (128 aa)
	A0A2G5C371	PA domain-containing protein. (538 aa)

Your Current Organism:

Aquilegia coerulea

NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2G5C4D0	A0A2G5CQI4	Ubiquitin-like domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.941
A0A2G5C4D0	A0A2G5DXP2	Ubiquitin-like domain-containing protein.	PUA domain-containing protein.	0.941
A0A2G5C4D0	A0A2G5E3I1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.635
A0A2G5C4D0	A0A2G5F6K4	Ubiquitin-like domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.941
A0A2G5CQI4	A0A2G5C4D0	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5CQI4	A0A2G5EYJ5	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5CQI4	A0A2G5F1J1	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5DE04	A0A2G5F5B8	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.992
A0A2G5DE04	A0A2G5F728	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.999
A0A2G5DE04	A0A2G5F7N7	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.992
A0A2G5DXP2	A0A2G5C4D0	PUA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5DXP2	A0A2G5EYJ5	PUA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5DXP2	A0A2G5F1J1	PUA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.941
A0A2G5E3I1	A0A2G5C4D0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.635
A0A2G5E3I1	A0A2G5EYJ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.635
A0A2G5E3I1	A0A2G5F1J1	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.635
A0A2G5EYJ5	A0A2G5CQI4	Ubiquitin-like domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.941
A0A2G5EYJ5	A0A2G5DXP2	Ubiquitin-like domain-containing protein.	PUA domain-containing protein.	0.941
A0A2G5EYJ5	A0A2G5E3I1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.635
A0A2G5EYJ5	A0A2G5F6K4	Ubiquitin-like domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.941