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gpmI gpmI fbp fbp prs prs A7J50_0806 A7J50_0806 A7J50_0807 A7J50_0807 A7J50_0808 A7J50_0808 A7J50_0809 A7J50_0809 A7J50_0810 A7J50_0810 A7J50_0882 A7J50_0882 A7J50_0883 A7J50_0883 A7J50_0884 A7J50_0884 A7J50_0885 A7J50_0885 A7J50_1088 A7J50_1088 eno eno A7J50_1691 A7J50_1691 tal tal A7J50_1928 A7J50_1928 A7J50_1929 A7J50_1929 tal-2 tal-2 A7J50_2312 A7J50_2312 A7J50_2344 A7J50_2344 A7J50_2356 A7J50_2356 A7J50_2374 A7J50_2374 A7J50_2774 A7J50_2774 A7J50_2932 A7J50_2932 A7J50_2933 A7J50_2933 tpiA tpiA deoC deoC A7J50_2955 A7J50_2955 rbsK rbsK A7J50_3221 A7J50_3221 zwf zwf A7J50_3248 A7J50_3248 A7J50_3500 A7J50_3500 A7J50_4578 A7J50_4578 A7J50_4606 A7J50_4606 pgl pgl zwf-2 zwf-2 A7J50_4609 A7J50_4609 glk glk edd edd A7J50_4734 A7J50_4734 A7J50_4793 A7J50_4793 A7J50_4794 A7J50_4794 A7J50_4795 A7J50_4795 A7J50_4796 A7J50_4796 A7J50_4797 A7J50_4797 A7J50_4804 A7J50_4804 A7J50_4805 A7J50_4805 A7J50_4807 A7J50_4807 A7J50_4808 A7J50_4808 A7J50_4809 A7J50_4809 pgi pgi tpiA-2 tpiA-2 glmM glmM A7J50_5288 A7J50_5288 A7J50_5426 A7J50_5426 A7J50_5428 A7J50_5428 pgk pgk A7J50_5433 A7J50_5433 rpiA rpiA A7J50_5787 A7J50_5787 glmS glmS glmU glmU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa)
fbpFructose-1,6-bisphosphatase class 1; Pfam:pfam00316 Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family. (336 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
A7J50_0806TatD family hydrolase; Pfam:pfam01026 TatD related DNase. (258 aa)
A7J50_0807Transcriptional regulator; Pfam:pfam00532 Periplasmic binding proteins and sugar binding domain of LacI family. (331 aa)
A7J50_0808PTS fructose transporter subunit IIA; Pfam:pfam02896 PEP-utilizing enzyme, TIM barrel domain; Belongs to the PEP-utilizing enzyme family. (952 aa)
A7J50_08091-phosphofructokinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (313 aa)
A7J50_0810PTS fructose transporter subunit IIBC; Pfam:pfam02302 PTS system, Lactose/Cellobiose specific IIB subunit. (572 aa)
A7J50_0882Phosphotransferase system, phosphocarrier protein HPr; Pfam:pfam00381 PTS HPr component phosphorylation site. (90 aa)
A7J50_0883glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities. (285 aa)
A7J50_0884PTS fructose transporter subunit IIA; Pfam:pfam00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (154 aa)
A7J50_0885Sigma N (Sigma 54) modulator RpoX; Pfam:pfam02482 Sigma 54 modulation protein / S30EA ribosomal protein. (101 aa)
A7J50_1088Glucose dehydrogenase; Pfam:pfam13360 PQQ-like domain. (805 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
A7J50_1691Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (308 aa)
A7J50_1928Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (471 aa)
A7J50_1929Hydroxypyruvate reductase; Pfam:pfam13660 Domain of unknown function (DUF4147). (426 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (307 aa)
A7J50_2312Fructose-bisphosphate aldolase. (97 aa)
A7J50_2344DeoR family transcriptional regulator; Pfam:pfam00455 DeoR C terminal sensor domain. (261 aa)
A7J50_2356Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa)
A7J50_2374Pfam:pfam02502 Ribose/Galactose Isomerase. (153 aa)
A7J50_2774Pfam:pfam02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (547 aa)
A7J50_2932Pfam:pfam00274 Fructose-bisphosphate aldolase class-I. (347 aa)
A7J50_2933Phosphoketolase; Pfam:pfam09364 XFP N-terminal domain. (808 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (227 aa)
A7J50_2955DeoR family transcriptional regulator; Pfam:pfam00455 DeoR C terminal sensor domain. (252 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (306 aa)
A7J50_32213-carboxymuconate cyclase; Pfam:pfam10282 Lactonase, 7-bladed beta-propeller. (391 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
A7J50_3248Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (327 aa)
A7J50_3500Pfam:pfam00171 Aldehyde dehydrogenase family. (538 aa)
A7J50_4578Gluconokinase; Pfam:pfam13671 AAA domain. (177 aa)
A7J50_4606Pfam:pfam01081 KDPG and KHG aldolase. (221 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (237 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (488 aa)
A7J50_4609Transcriptional regulator; Pfam:pfam01418 Helix-turn-helix domain, rpiR family. (289 aa)
glkGlucokinase; Pfam:pfam02685 Glucokinase; Belongs to the bacterial glucokinase family. (318 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
A7J50_4734Pfam:pfam00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
A7J50_4793GntR family transcriptional regulator; Pfam:pfam07702 UTRA domain. (252 aa)
A7J50_4794N-acetylglucosamine-6-phosphate deacetylase; Pfam:pfam13594 Amidohydrolase. (368 aa)
A7J50_4795Iron dicitrate transport regulator FecR; Pfam:pfam01380 SIS domain. (340 aa)
A7J50_4796N-acetyl-D-glucosamine phosphotransferase system transporter; Pfam:pfam02896 PEP-utilizing enzyme, TIM barrel domain. (836 aa)
A7J50_4797Pfam:pfam02378 Phosphotransferase system, EIIC. (568 aa)
A7J50_4804PTS glucose transporter subunit IIB. (92 aa)
A7J50_4805PTS mannose transporter subunit IIC; Pfam:pfam02896 PEP-utilizing enzyme, TIM barrel domain. (846 aa)
A7J50_4807Trehalose-6-phosphate hydrolase; Pfam:pfam00128 Alpha amylase, catalytic domain. (548 aa)
A7J50_4808Trehalose permease IIC protein; Pfam:pfam02378 Phosphotransferase system, EIIC. (480 aa)
A7J50_4809Trehalose operon repressor; Pfam:pfam07702 UTRA domain. (234 aa)
pgiPfam:pfam00342 Phosphoglucose isomerase; Belongs to the GPI family. (554 aa)
tpiA-2Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
A7J50_5288Pfam:pfam00834 Ribulose-phosphate 3 epimerase family; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
A7J50_5426Fructose-bisphosphate aldolase. (97 aa)
A7J50_5428Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPfam:pfam00162 Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
A7J50_5433Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa)
A7J50_5787Pfam:pfam01263 Aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (299 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
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